The Business Research Company’s 2026 market reports include new capabilities such as market attractiveness scoring and analysis, total addressable market analysis, company scoring matrix, interactive excel data dashboard, improved supply chain analysis, upcoming startups in the market, and overview of key products, aimed at improving the depth, usability, and strategic value of the insights delivered.
How Much Is The HERG Screening Market Expected To Grow In Terms Of Market Value Between 2026 And 2030?
The herg screening market size has experienced rapid growth over recent years. It is projected to increase from $1.84 billion in 2025 to $2.06 billion in 2026, demonstrating a compound annual growth rate (CAGR) of 12.0%. This historical expansion can be linked to a rise in cardiac-related drug withdrawals, heightened investment in preclinical safety studies, the ongoing development of pharmaceutical R&D, the utilization of in-vitro ion channel assays, and greater awareness concerning drug-induced arrhythmias.
The herg screening market is projected for substantial expansion over the upcoming years. Its valuation is anticipated to reach $3.21 billion by 2030, demonstrating a compound annual growth rate (CAGR) of 11.7%. This projected growth during the forecast period is largely due to several factors, including developments in AI-driven predictive toxicology, the incorporation of organ-on-chip technologies, the proliferation of biologics and personalized medicine, an increase in outsourcing activities to CDMOs, and the broadening of preclinical research in developing markets. Key developments anticipated in this period encompass sophisticated cardiotoxicity modeling, automated high-throughput screening, the adoption of predictive analytics in preclinical safety evaluations, an increase in contract research services, and the use of miniaturized microfluidic assays.
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What Drivers Are Influencing The HERG Screening Market?
The HERG screening market is projected to grow as the number of individuals affected by heart disorders increases. These conditions, also referred to as cardiovascular disorders or diseases, encompass various ailments impacting the heart and blood vessels. Such conditions can hinder the heart’s proper functioning and potentially result in severe health complications. Unhealthy lifestyles, an aging population, genetic factors, diabetes, and metabolic syndrome are among the causes of these disorders. HERG screening assists in identifying suitable drug candidates, preventing adverse cardiac events that might induce life-threatening cardiac arrhythmias, particularly torsade de pointes (TdP), and improving patient outcomes. For instance, in October 2025, according to the Australian Institute of Health and Welfare, an Australia-based government agency reported that in 2023, an estimated 57,100 adults aged 25 and above experienced acute coronary events, averaging roughly 156 incidents per day. Therefore, the growing count of patients with heart disorders is propelling the expansion of the HERG screening market.
What Major Segment Divisions Exist Within The HERG Screening Market?
The herg screening market covered in this report is segmented –
1) By Type: Gene KCNH2, Mutant KCNH2
2) By Ion Channel: Voltage-Gated, Ligand Gated
3) By Applications: Antiarrhythmic, Antipsychotic, Antibiotics, Other Applications
Subsegments:
1) By Gene KCNH2: Wild-Type KCNH2, Recombinant KCNH2
2) By Mutant KCNH2: Mutations: Missense Mutations, Nonsense Mutations, Frameshift Mutations
How Are Trends Shaping The Direction Of The HERG Screening Market?
Leading companies operating in the HERG screening market are focusing on new, innovative advanced solutions, such as GLP-certified HERG screening services, to improve cardiac safety assessments during drug development processes. This service refers to the good laboratory practice-certified screening of the human ether-à-go-go related gene (hERG) using the traditional whole-cell patch-clamp technique. It ensures that the screening is carried out in accordance with regulatory guidelines like ICH S7A and ICH S7B, which are crucial for safety pharmacology studies in drug development. For instance, in August 2023, Metrion Biosciences Ltd., a UK-based pharmaceutical company, introduced its good laboratory practice (GLP)-certified hERG screening service. This service aims to bolster Metrion’s support for small-molecule therapeutic development and enhance the company’s existing cardiac safety service portfolio. Additionally, this service employs the conventional whole-cell patch-clamp technique to evaluate potential cardiac liabilities before humans enter Phase 1 clinical trials, offers regulatory guidance for safety pharmacology studies in drug development, and provides clients with high-quality biology services for ion channel targets.
Which Companies Are Leading Innovation In The HERG Screening Market?
Major companies operating in the herg screening market are Eurofins-Cerep SA, Aviva Biosciences Inc., AstraZeneca Public Limited Company, Merck KGaA, Charles River Laboratories Inc., Abcam Public Limited Company, Molecular Devices LLC, Caliper Life Sciences Inc., ChanTest Corporation, Creative Bioarray Inc., Cellular Dynamics International Inc., Nanion Technologies, Essen Bioscience, ACEA Biosciences Inc., Metrion Biosciences Inc., Aurora Biomed Inc., Aureus Sciences, RedShift BioAnalytics, Sophion Bioscience Inc., Fluxion Biosciences Inc.
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Which Regions Are Expected To Experience Rapid Expansion In The HERG Screening Market?
North America was the largest region in the HERG screening market in 2025. Asia-Pacific is expected to be the fastest growing region in the forecast period. The regions covered in the herg screening market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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