Pharmaceuticals

Non-Alcoholic Steatohepatitis (NASH) Market to Grow at a CAGR of 32.3% from 2025 to 2029

November 10, 2025 by Marketing Posting

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What Is The Future Market Size Estimation For The Non-Alcoholic Steatohepatitis (NASH) Market Covering 2025–2034?

The market size for non-alcoholic steatohepatitis (NASH) has experienced substantial expansion in recent years. Projections indicate it will advance from $4.5 billion in 2024 to $6.06 billion by 2025, propelled by a compound annual growth rate (CAGR) of 34.7%. This historical market expansion is primarily attributable to factors such as the increasing prevalence of NASH, the global obesity epidemic, rising awareness and diagnostic efforts, evolving lifestyle and dietary patterns, and improvements in healthcare infrastructure.

The non-alcoholic steatohepatitis (NASH) market size is anticipated to undergo significant expansion over the next few years. It is projected to reach $18.55 billion by 2029, growing at a compound annual growth rate (CAGR) of 32.3%. This growth during the forecast period can be attributed to advancements in NASH drug development, increasing NASH screening initiatives, rising healthcare expenditure, collaborative research efforts, and government support and regulations. Prominent trends expected in this period include a focus on lifestyle interventions and patient education, enhanced collaboration in clinical research, regulatory improvements and pathway designations, and the integration of artificial intelligence in diagnosis and monitoring.

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Which Major Market Drivers Are Shaping The Future Of The Non-Alcoholic Steatohepatitis (NASH) Market?

The increasing prevalence of obesity is fueling demand for the non-alcoholic steatohepatitis (NASH) market moving forward. Obesity is defined as an abnormal or excessive accumulation of fat that poses a health risk, or body weight exceeding what is considered healthy or typical for an individual of a specific height. As non-alcoholic fatty liver disease has become more common due to the rising obesity pandemic, NASH is anticipated to become the most widespread cause of severe liver disease in the coming decades, thereby driving the need for NASH treatments and related drugs. For instance, in March 2024, the World Health Organization (WHO), a UK-based international public health organization, reported that in 2022, approximately 2.5 billion adults aged 18 and older were categorized as overweight, with 890 million of them experiencing obesity. Consequently, the increase in obesity cases will propel the growth of the non-alcoholic steatohepatitis (NASH) market.

What Are The Major Segment Categories Driving The Non-Alcoholic Steatohepatitis (NASH) Market Growth?

The non-alcoholic steatohepatitis (nash) market covered in this report is segmented –

1) By Type: Solid, Liquid

2) By Product: Vitamin E and Pioglitazone, Ocaliva, Elafibranor, Selonsertib and Cenicriviroc, Other Products

3) By Disease Cause: Hypertension, Heart Disease, High Blood Lipid, Type 2 Diabetes, Obesity

4) By Sales Channel: Hospital Pharmacy, Retail Pharmacy, Online Provider

5) By Application: Oral, Parenteral

Subsegments:

1) By Solid: Tablets, Capsules, Other Solid Dosage Forms

2) By Liquid: Oral Solutions, Syrups, Injectable Solutions, Other Liquid Dosage Forms

Which Key Trends Are Expected To Influence The Non-Alcoholic Steatohepatitis (NASH) Market In The Coming Years?

Major companies in the non-alcoholic steatohepatitis (NASH) market are developing thyroid hormone receptor-beta (THR-beta) agonists with the goal of improving liver metabolism, decreasing liver fat accumulation, and enhancing liver function. Thyroid hormone receptor-beta (THR-beta) agonists are compounds that specifically activate the thyroid hormone receptor-beta subtype, a vital receptor involved in regulating metabolism, growth, and development. For instance, in March 2024, the Food and Drug Administration, a US-based regulatory body, approved Rezdiffra (resmetirom), a thyroid hormone receptor-beta agonist, as the first treatment for adults experiencing noncirrhotic NASH with moderate to advanced liver scarring (fibrosis). By selectively engaging the THR-beta receptor, Rezdiffra aids in regulating lipid metabolism, which leads to a reduction in intrahepatic triglycerides and overall liver fat accumulation.

Who Are The Major Companies Operating In The Non-Alcoholic Steatohepatitis (NASH) Market?

Major companies operating in the non-alcoholic steatohepatitis (NASH) market include NGM Biopharmaceuticals Inc., Novartis AG, AstraZeneca plc., GlaxoSmithKline plc., F. Hoffmann-La Roche AG, The Takeda Pharmaceutical Company Limited, Gilead Sciences Inc., Novo Nordisk A/S, Genfit SA, Cadila Pharmaceuticals Ltd., Intercept Pharmaceuticals Inc., Enanta Pharmaceuticals Inc., Blade Therapeutics Inc., Galmed Pharmaceuticals Inc., Immuron Limited, Terns Pharmaceuticals Inc., Tobira Therapeutics Inc., Arena Pharmaceuticals Inc., Galectin Therapeutics Inc., Viking Therapeutics, Madrigal Pharmaceuticals Inc., Cirius Therapeutics, Akero Therapeutics Inc., Echosens.

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How Does The Non-Alcoholic Steatohepatitis (NASH) Market Perform Across Key Geographic Regions?

North America was the largest region in the non alcoholic steatohepatitis (NASH) market share in 2024. The regions covered in the non-alcoholic steatohepatitis (nash) market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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