Pharmaceuticals

HERG Screening Industry Forecast to Hit $2.88 Billion by 2029 With a Strong 11.9% CAGR

November 10, 2025 by Marketing Posting

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#What Are The Current (2025) And Forecast (2029) Sizes Of The HERG Screening Market?

The HERG screening market size has observed swift expansion in recent years. It is anticipated to grow from $1.62 billion in 2024 to $1.84 billion in 2025, maintaining a compound annual growth rate (CAGR) of 13.7%. This historic growth is linked to factors such as increasing drug development activities, stricter regulatory requirements, heightened awareness of cardiac safety, and a rising incidence of cardiac disorders.

The HERG screening market size is anticipated to undergo significant expansion in the next few years. It is predicted to reach “$2.88 billion in 2029, demonstrating a compound annual growth rate (CAGR) of 11.9%”. This growth throughout the forecast period can be attributed to several factors, including the proliferation of personalized medicine, an increase in the outsourcing of drug development activities, advancements in emerging markets and research, and a heightened focus on non-cardiac safety assessments. Major trends identified for the forecast period encompass the development of advanced in vitro models, the integration of genomic and proteomic data, ongoing advancements in computational approaches, a dedicated focus on pediatric drug safety, and collaborative efforts for data sharing and standardization.

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Which Drivers Are Impacting The HERG Screening Market?

The HERG screening market is projected to expand due to the increasing number of patients diagnosed with heart disorders. These conditions, also known as cardiovascular disorders or diseases, encompass a variety of ailments affecting the heart and its blood vessels. Such disorders can impede the heart’s ability to function correctly and potentially lead to serious health complications. They are often attributed to unhealthy lifestyles, an aging population, genetic factors, diabetes, and metabolic syndrome. HERG screening plays a vital role in identifying prospective drug candidates, preventing adverse cardiac events that might induce life-threatening cardiac arrhythmias, especially torsade de pointes (TdP), and enhancing patient outcomes. For instance, in May 2023, a report published by the Centers for Disease Control and Prevention, a US-based national public health agency, indicated that 1 in 20 adults aged 20 and above suffer from cardiovascular diseases, with 695,000 individuals impacted and 375,476 deaths attributed to these conditions. Additionally, in March 2022, data from the Office for National Statistics, a UK-based government department, revealed 20,061 fatalities from heart attacks, marking an increase from the previous year. Consequently, the rising prevalence of patients with heart disorders is a significant factor driving the growth of the HERG screening market.

What Are The Major Segment Types Covered In The HERG Screening Market?

The herg screening market covered in this report is segmented –

1) By Type: Gene KCNH2, Mutant KCNH2

2) By Ion Channel: Voltage-Gated, Ligand Gated

3) By Applications: Antiarrhythmic, Antipsychotic, Antibiotics, Other Applications

Subsegments:

1) By Gene KCNH2: Wild-Type KCNH2, Recombinant KCNH2

2) By Mutant KCNH2: Mutations: Missense Mutations, Nonsense Mutations, Frameshift Mutations

What Are The Major Trends Driving The Growth Of The HERG Screening Market?

Leading firms within the HERG screening market are concentrating on advanced and innovative solutions, such as GLP-certified HERG screening services, to enhance cardiac safety assessments throughout drug development processes. This service entails the good laboratory practice-certified screening of the human ether-à-go-go related gene (hERG) using the established whole-cell patch-clamp technique. It ensures that the screening adheres to regulatory guidelines like ICH S7A and ICH S7B, which are crucial for safety pharmacology studies in drug development. For instance, in August 2023, Metrion Biosciences Ltd., a UK-based pharmaceutical company, launched its good laboratory practice (GLP)-certified hERG screening service. This offering is designed to bolster Metrion’s support for small-molecule therapeutic development and complement the company’s existing cardiac safety service portfolio. Additionally, this service utilizes the conventional whole-cell patch-clamp technique to assess potential cardiac liabilities before entering Phase 1 clinical trials in humans, provides regulatory guidance for safety pharmacology studies in drug development, and offers clients high-quality biology services for ion channel targets.

Who Are The Key Multinational Companies Dominating The HERG Screening Market?

Major companies operating in the HERG screening market are Eurofins-Cerep SA., Aviva Biosciences Inc., AstraZeneca Public Limited Company, Merck KGaA, Charles River Laboratories Inc., Abcam Public Limited Company, Molecular Devices LLC, Caliper Life Sciences Inc., Crprotex Limited, ChanTest Corporation, Creative bioarray Inc., Cellular Dynamics International Inc., Nanion Technologies, Essen Bioscience, ABR-Affinity BioReagents Inc., ACEA Biosciences Inc., Metrion biosciences Inc., Aurora Biomed Inc., Aureus Sciences, RedShift BioAnalytics, B’SYS GmbH, Cambridge Bioscience Ltd., Sophion Bioscience Inc., Fluxion Biosciences Inc., ChemAxon Ltd.

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Which Region Is Expected To Witness The Fastest Growth In The HERG Screening Market?

North America was the largest region in the HERG screening market in 2024. Asia-Pacific is expected to be the fastest growing region in the forecast period. The regions covered in the HERG screening market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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