Global HERG Screening Market Valuation and Growth Prospects: $2.88 Billion by 2029

Uncover key drivers, emerging technologies, and competitive movements shaping the herg screening market from 2025–2034 with trusted insights from The Business Research Company

What Are The Future Growth Projections For The HERG Screening Market Size?

The HERG screening market size has experienced rapid expansion in recent years. Its value is expected to rise from $1.62 billion in 2024 to $1.84 billion in 2025, achieving a compound annual growth rate (CAGR) of 13.7%. This historical growth can be attributed to an increase in drug development activities, regulatory requirements, heightened awareness of cardiac safety, and a growing incidence of cardiac disorders.

The HERG screening market is anticipated to expand significantly in the near future, with projections showing it will reach $2.88 billion by 2029, exhibiting a compound annual growth rate (CAGR) of 11.9%. This upward trend during the forecast period is primarily driven by the proliferation of personalized medicine, an increase in outsourced drug development tasks, the rise of new markets and research efforts, and a renewed emphasis on non-cardiac safety assessments. Dominant trends for this period are expected to encompass advanced in vitro models, the merging of genomic and proteomic information, progress in computational techniques, a specific focus on pediatric drug safety, and collaborative initiatives for data exchange and standardization.

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What Core Market Drivers Are Expanding The HERG Screening Industry?

The increasing number of individuals afflicted with heart disorders is expected to propel the expansion of the HERG screening market in the future. Heart disorders, also known as cardiovascular disorders or diseases, refer to a spectrum of conditions that impact the heart and blood vessels. These conditions can impair the heart’s ability to function correctly and potentially lead to serious health complications. Such disorders often arise due to unhealthy lifestyles, an aging demographic, genetic predispositions, diabetes, and metabolic syndrome. HERG screening assists in identifying promising drug candidates, preventing adverse cardiac events that could induce life-threatening cardiac arrhythmias, particularly torsade de pointes (TdP), and enhancing patient outcomes. For instance, in May 2023, a report published by the Centers for Disease Control and Prevention, a US-based national public health agency, indicated that 1 in 20 adults aged 20 and above have cardiovascular diseases, with 695,000 people suffering from these diseases and 375,476 people dying from them. Furthermore, in March 2022, according to a report from the Office for National Statistics, a UK-based government department, 20,061 individuals died of heart attacks, marking an increase from the prior year. Consequently, the rising incidence of heart disorders among patients is driving the growth of the HERG screening market.

What Segment Insights Are Highlighted In The HERG Screening Market Report?

The herg screening market covered in this report is segmented –

1) By Type: Gene KCNH2, Mutant KCNH2

2) By Ion Channel: Voltage-Gated, Ligand Gated

3) By Applications: Antiarrhythmic, Antipsychotic, Antibiotics, Other Applications

Subsegments:

1) By Gene KCNH2: Wild-Type KCNH2, Recombinant KCNH2

2) By Mutant KCNH2: Mutations: Missense Mutations, Nonsense Mutations, Frameshift Mutations

Which Notable Trends Are Transforming The HERG Screening Market Outlook?

Major companies operating in the HERG screening market are focusing on new innovative advanced solutions, such as GLP-certified HERG screening services, to enhance cardiac safety assessments during drug development. This service involves the good laboratory practice-certified screening of the human ether-à-go-go related gene (hERG) utilizing the conventional whole-cell patch-clamp technique. It ensures the screening is conducted in compliance with regulatory guidelines like ICH S7A and ICH S7B, which are vital for safety pharmacology studies in drug development. For instance, in August 2023, Metrion Biosciences Ltd., a UK-based pharmaceutical company, launched its good laboratory practice (GLP)-certified hERG screening service. This service aims to bolster Metrion’s support for small-molecule therapeutic development and complement the company’s existing cardiac safety service portfolio. Additionally, this service employs the conventional whole-cell patch-clamp technique to assess potential cardiac liabilities before entering Phase 1 clinical trials in humans, provides regulatory guidance for safety pharmacology studies in drug development, and offers clients high-quality biology services for ion channel targets.

Which Firms Are Driving Innovation Within The HERG Screening Market?

Major companies operating in the HERG screening market are Eurofins-Cerep SA., Aviva Biosciences Inc., AstraZeneca Public Limited Company, Merck KGaA, Charles River Laboratories Inc., Abcam Public Limited Company, Molecular Devices LLC, Caliper Life Sciences Inc., Crprotex Limited, ChanTest Corporation, Creative bioarray Inc., Cellular Dynamics International Inc., Nanion Technologies, Essen Bioscience, ABR-Affinity BioReagents Inc., ACEA Biosciences Inc., Metrion biosciences Inc., Aurora Biomed Inc., Aureus Sciences, RedShift BioAnalytics, B’SYS GmbH, Cambridge Bioscience Ltd., Sophion Bioscience Inc., Fluxion Biosciences Inc., ChemAxon Ltd.

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What Regional Trends Are Shaping Growth In The HERG Screening Market?

North America was the largest region in the HERG screening market in 2024. Asia-Pacific is expected to be the fastest growing region in the forecast period. The regions covered in the HERG screening market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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