The Business Research Company’s 2026 market reports include new capabilities such as market attractiveness scoring and analysis, total addressable market analysis, company scoring matrix, interactive excel data dashboard, improved supply chain analysis, upcoming startups in the market, and overview of key products, aimed at improving the depth, usability, and strategic value of the insights delivered.
What Market Valuation Is Forecasted For The NGS-Based RNA-Sequencing Market By 2030 Starting From Its 2026 Size?
The ngs-based rna-sequencing market’s scale has expanded rapidly in recent times. It will grow from $4.2 billion in 2025 to $5.27 billion in 2026 at a compound annual growth rate (CAGR) of 25.3%. Historically, this growth has stemmed from factors such as the broadening of genomic research initiatives, a decrease in the cost of sequencing technologies, greater application of rna-seq in academic studies, the advent of sophisticated sequencing platforms, and advancements in bioinformatics capabilities.
The ngs-based rna-sequencing market is projected to experience substantial expansion over the coming years. Its valuation is forecast to reach $12.73 billion by 2030, exhibiting a compound annual growth rate (CAGR) of 24.7%. This expansion during the projection period stems from factors such as the greater acceptance of RNA sequencing in clinical diagnostics, increased funding in precision medicine, broader applications in pharmaceutical research, the rising need for integrated data analysis solutions, and a heightened emphasis on multi-omics research. Key developments anticipated over the forecast period involve the wider adoption of high-throughput RNA sequencing platforms, a surge in demand for single-cell RNA sequencing, the increasing utilization of cloud-based bioinformatics analysis, the broadening scope of transcriptomics within precision medicine, and a stronger focus on data precision and scalability.
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What Drivers Are Shaping The Future Growth Of The NGS-Based RNA-Sequencing Market?
The expanding pharmaceutical sector is anticipated to propel the advancement of the NGS-based RNA-sequencing market moving forward. This industry encompasses the discovery, development, and production of medicines and drugs by both governmental and private entities. The pharmaceutical industry utilizes NGS-based RNA-sequencing to thoroughly analyze gene expression, pinpoint potential drug targets, assess drug responses, and understand disease mechanisms, thereby facilitating drug discovery and development with a deeper understanding of molecular processes. For instance, in June 2025, according to the Centers for Medicare & Medicaid Services (CMS), a US-based federal agency, spending on prescription drugs climbed 11.4% in 2023 to $449.7 billion, an acceleration from the 7.8% growth seen in 2022. Therefore, the expanding pharmaceutical industry is fueling the growth of the NGS-based RNA-sequencing market.
Which Segment Categories Define The NGS-Based RNA-Sequencing Market?
The ngs-based rna-sequencing market covered in this report is segmented –
1) By Product And Service: Sample Preparation Products, Sequencing Platforms and Consumables, Sequencing Services, Data Analysis, Storage, and Management
2) By Technology: Sequencing by Synthesis, Ion Semiconductor Sequencing, Single-molecule Real-time Sequencing, Nanopore Sequencing
3) By Application: Expression Profiling Analysis, Small RNA Sequencing, De Novo Transcriptome Assembly
4) By End User: Research & Academia, Pharmaceutical & Biotechnology Companies, Other End Users
Subsegments:
1) By Sample Preparation Products: RNA Extraction Kits, Library Preparation Kits, Reverse Transcription Kits, Quality Control Reagents
2) By Sequencing Platforms And Consumables: Sequencing Instruments, Sequencing Consumables
3) By Sequencing Services: Contract Sequencing Services, Custom Library Preparation Services, Consultation And Experimental Design Services
4) By Data Analysis, Storage, And Management: Bioinformatics Software, Data Analysis Services, Cloud-Based Data Storage Solutions, Data Management Platforms
What Major Market Trends Are Driving Changes In The NGS-Based RNA-Sequencing Market?
Leading entities within the NGS-based RNA-sequencing market are directing their efforts toward creating inventive products, such as sophisticated small RNA-seq kits, to optimize workflows and enhance the precision and effectiveness of RNA expression analysis. These advanced small RNA-seq kits represent cutting-edge library preparation tools specifically designed to capture and sequence small RNAs with high accuracy, assisting researchers in shortening workflow duration, minimizing extraneous elements like adapter dimers, and achieving more precise and consistent expression profiling. As an illustration, in October 2025, Lexogen, an Austria-based biotechnology company, introduced the miRVEL Profiling Small RNA-Seq Library Prep Kit, which aims to simplify and refine small RNA research processes. This innovative kit provides a quicker and more dependable workflow, enabling the preparation of sequencing-ready libraries in less than seven hours with minimal manual intervention. It incorporates advanced adapter blocking technology to inhibit adapter dimer formation, ensures consistent outcomes across different input quantities, and integrates 8 nt unique dual indices (UDIs) for precise multiplexing and read allocation. The miRVEL Profiling Kit supports a wide array of uses, including RNA interference investigations, studies of host-defense mechanisms, and small RNA research in plant or agricultural contexts. Furthermore, it is compatible with Lexogen’s SPLIT RNA extraction kits and TraPR small RNA enrichment system, offering a comprehensive, complete solution for small RNA analysis.
Who Are The Top Companies Competing In The NGS-Based RNA-Sequencing Market?
Major companies operating in the ngs-based rna-sequencing market are Illumina Inc., Thermo Fisher Scientific Inc., Oxford Nanopore Technologies Ltd., Agilent Technologies Inc., BGI Group, QIAGEN N.V., Eurofins Scientific SE, Bio-Rad Laboratories Inc., F. Hoffmann-La Roche Ltd., Takara Bio Inc., GENEWIZ Inc., Novogene Corporation, Macrogen Inc., Zymo Research Corp., Lexogen GmbH, Partek Incorporated, GATC Biotech AG, Genohub LLC, BaseClear B.V., Otogenetics Corporation, SeqLL LLC, GenXPro GmbH, Genotypic Technology Pvt. Ltd.
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Which Geographic Regions Are Influencing Demand In The NGS-Based RNA-Sequencing Market?
North America was the largest region in the NGS-based RNA sequencing market in 2025. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the ngs-based rna-sequencing market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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