Isosorbide mononitrate tablet market growth is driven by rising cardiovascular disease prevalence

Global Isosorbide Mononitrate Tablet Market

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What Is The Forecasted Market Size Trajectory Of The Isosorbide Mononitrate Tablet Market From 2026 To 2030?

The isosorbide mononitrate tablet market size has demonstrated robust growth in recent years. It is anticipated to expand from $1.2 billion in 2025 to $1.26 billion in 2026, registering a compound annual growth rate (CAGR) of 5.3%. The market’s expansion historically can be ascribed to an increase in the prevalence of coronary artery disease, the prolonged use of nitrates in angina management, a rising aging population, the availability of cost-effective generic drugs, and the development of hospital and retail pharmacy infrastructure.

The isosorbide mononitrate tablet market size is projected to experience robust expansion over the coming years. It is anticipated to grow to $1.55 billion in 2030, exhibiting a compound annual growth rate (CAGR) of 5.3%. This growth during the forecast period can be attributed to the rise in chronic cardiovascular conditions, increasing demand for extended-release tablets, rising adoption of online pharmacies, improved diagnosis of angina and heart failure, and expanding access to cardiovascular medicines in emerging markets. Major trends foreseen in this period include long-acting cardiovascular maintenance therapies, a rising preference for extended-release formulations, the growing use of generic nitrate medications, improved patient adherence through once-daily dosing, and the expansion of online and retail pharmacy access.

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What Key Factors Are Shaping The Isosorbide Mononitrate Tablet Market Landscape?

The increasing incidence of heart and blood vessel conditions is anticipated to fuel the expansion of the isosorbide mononitrate tablet market in the future. These conditions, known as CVDs, encompass ailments like coronary artery disease, heart failure, and hypertension, which impact the heart and its associated blood vessels. A key factor behind this increase is poor dietary habits, characterized by excessive saturated fats, trans fats, sodium, and added sugars, which contribute to health issues such as obesity, high blood pressure, and elevated cholesterol levels. Isosorbide mononitrate tablets play a role in treating cardiovascular diseases by promoting the relaxation and dilation of blood vessels. This action enhances blood circulation, lessens the strain on the heart, mitigates chest pain (angina), decreases blood pressure, and boosts oxygen supply to the cardiac muscle. An illustrative example highlights this trend: the American College of Cardiology, a US-based medical non-profit and cardiologists’ professional body, reported from the Global Burden of Disease study in September 2025 that global cardiovascular disease fatalities reached 19.2 million in 2023. Consequently, the escalating occurrence of cardiovascular diseases is a primary catalyst for the expansion of the isosorbide mononitrate tablet market.

Which Segment Categories Are Included In The Isosorbide Mononitrate Tablet Market Segment Analysis?

The isosorbide mononitrate tablet market covered in this report is segmented –

1) By Dosage Form: Immediate-Release Tablets, Extended-Release Tablets

2) By Indication Type: Angina Pectoris, Coronary Artery Disease (CAD)

3) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies

Subsegments:

1) By Immediate-Release Tablets: Low-Dose, Single Strength Tablets

2) By Extended-Release Tablets: Moderate-Dose, High-Dose, Once-Daily Formulation, Twice-Daily Formulation

What Market Trends Are Affecting The Isosorbide Mononitrate Tablet Market?

Companies operating in the isosorbide mononitrate tablet market are prioritizing the development of innovative products, such as extended-release (ER) formulations. This strategic focus aims to enhance patient compliance, provide sustained therapeutic effects, and optimize treatment outcomes for conditions like angina pectoris. An extended-release formulation is an advanced drug delivery system designed to gradually release medication over an extended period, which helps in reducing dosing frequency and maintaining consistent blood levels. For instance, in February 2024, Zydus Lifesciences Limited, an India-based pharmaceutical manufacturing company, obtained approval from the United States Food and Drug Administration (USFDA) to manufacture and market isosorbide mononitrate extended-release tablets USP in strengths of 30 mg, 60 mg, and 120 mg. These tablets are prescribed to prevent chest pain (angina) in patients with coronary artery disease and are considered equivalent to the reference listed drug (RLD), imdur extended-release tablets.

Who Are The Active Companies Shaping The Isosorbide Mononitrate Tablet Market?

Major companies operating in the isosorbide mononitrate tablet market are Pfizer Inc., Merck & Co., Inc., AstraZeneca plc, Abbott Laboratories, Teva Pharmaceutical Industries Ltd., Sun Pharmaceutical Industries Ltd., Aurobindo Pharma Ltd., Cipla Ltd., Zydus Lifesciences Limited, Torrent Pharmaceuticals Ltd., Micro Labs Ltd., Lupin Limited, Dr. Reddy’s Laboratories Ltd., Glenmark Pharmaceuticals Ltd., Alkem Laboratories Ltd., Mylan N.V., Hikma Pharmaceuticals PLC, Sandoz International GmbH, Qilu Pharmaceutical Co., Ltd., Lunan Pharmaceutical Group, Shandong Keyuan Pharmaceutical Co., Ltd.

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Which Region Leads The Isosorbide Mononitrate Tablet Market In Terms Of Market Share?

North America was the largest region in the isosorbide mononitrate tablet market in 2025. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the isosorbide mononitrate tablet market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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