Rise In Rare Disease Diagnoses Fueling The Growth Of The Market Due To Improving Genetic Testing And Diagnostics Is Supporting Development Across The Angioedema Treatment Market

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By 2030, How Much Growth In Market Size Is Expected For The Angioedema Treatment Market?

The angioedema treatment market has shown significant growth in its size over recent years. It is forecast to rise from $3.13 billion in 2025 to $3.59 billion in 2026, achieving a compound annual growth rate (CAGR) of 14.8%. The expansion during the preceding period is attributable to elements like emergency allergy management, hospital-based care, the application of corticosteroids, the accessibility of antihistamines, and the constrained number of targeted drugs.

The angioedema treatment market is projected to experience substantial expansion in the coming years, reaching $6.18 billion in 2030 at a compound annual growth rate (CAGR) of 14.5%. This anticipated growth is driven by factors such as advancements in biologic drug development, the expansion of genetic testing, the establishment of specialized allergy clinics, enhanced patient education, and a heightened emphasis on preventive care. Key developments during this period will involve a rise in the application of targeted bradykinin therapies, an increase in hereditary angioedema treatments, the broadening of emergency treatment guidelines, greater diagnostic understanding, and a focus on preventative interventions.

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Which Major Factors Are Contributing To The Development Of The Angioedema Treatment Market?

A growing prevalence of rare diseases is projected to stimulate the expansion of the angioedema treatment market moving forward. These medical conditions impact a minimal segment of the population, frequently presenting with restricted therapeutic options and considerable health consequences. The heightened occurrence of rare diseases is attributed to breakthroughs in genetic testing and diagnostic technologies, which empower healthcare providers to identify and precisely diagnose conditions that were previously undetected, thus contributing to an elevated reported prevalence. Angioedema treatment offers benefits for rare ailments like hereditary angioedema through focused treatments that assist in preventing and controlling severe swelling episodes, thereby enhancing patient results. For example, in November 2024, the Food and Drug Administration, a US-based federal agency, reported that over 7,000 rare diseases affected more than 30 million individuals in the United States. Consequently, the increasing incidence of rare diseases is fueling the growth of the angioedema treatment market.

How Is The Angioedema Treatment Market Examined Through Segment Analysis?

The angioedema treatment market covered in this report is segmented –

1) By Type: Allergic Angioedema, Drug-Induced Angioedema, Idiopathic Angioedema, Hereditary Angioedema

2) By Route Of Administration: Injection, Oral

3) By End Use: Hospitals, Clinics, Research Organizations

Subsegments:

1) By Allergic Angioedema: Antihistamines, Corticosteroids, Epinephrine, Immunotherapy, Allergen Avoidance Therapies

2) By Drug-Induced Angioedema: Discontinuation of Causative Drug, Antihistamines, Corticosteroids, Epinephrine, Bradykinin Pathway Inhibitors

3) By Idiopathic Angioedema: Empirical Antihistamine Therapy, Corticosteroid Therapy, Leukotriene Receptor Antagonists, Monoclonal Antibodies, Observation and Symptom Management

4) By Hereditary Angioedema: C1 Esterase Inhibitor Replacement Therapy, Bradykinin B2 Receptor Antagonists, Kallikrein Inhibitors, Attenuated Androgens, Antifibrinolytics

Which Trends Are Influencing The Expansion Of The Angioedema Treatment Market?

Leading companies in the angioedema treatment market are concentrating on developing innovative solutions, such as subcutaneous injections, to provide more convenient and rapid relief for patients experiencing acute hereditary angioedema (HAE) attacks. Subcutaneous injections involve administering medication into the fatty tissue just beneath the skin for its slow and steady absorption into the bloodstream. As an illustration, in April 2025, CSL Limited, an Australia-based biotechnology company, introduced ANDEMBRY (garadacimab). This product is a novel, fully human monoclonal antibody treatment aimed at preventing acute attacks in patients with hereditary angioedema (HAE). ANDEMBRY represents the first pre-filled pen for once-monthly subcutaneous administration, offering a convenient long-term prophylactic option. The drug functions by inhibiting activated Factor XII (Factor XIIa), which is a key initiator in the cascade that leads to angioedema. This marks a significant advancement in HAE management by delivering effective, patient-centric disease control.

Who Are The Major Companies Operating In The Angioedema Treatment Market?

Major companies operating in the angioedema treatment market are Sanofi SA, Takeda Pharmaceutical Company Limited, Viatris Inc., Otsuka Pharmaceutical Co. Ltd., Fresenius Kabi AG, Bausch Health Companies Inc., Apotex Inc., Aurobindo Pharma Ltd., Dr. Reddy’s Laboratories Ltd, Cipla Inc., Alnylam Pharmaceuticals Inc, Ionis Pharmaceuticals Inc., Salix Pharmaceuticals Ltd, BioCryst Pharmaceuticals Inc., Pharming Group NV, Pharvaris Netherlands B.V, Astria Therapeutics, Intellia Therapeutics, KalVista Pharmaceuticals Ltd., ADARx Pharmaceuticals, Adverum Biotechnologies Inc.

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Which Region Leads The Angioedema Treatment Market By Size?

North America was the largest region in the angioedema treatment market in 2025. The regions covered in the angioedema treatment market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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