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How Much Larger Will The Gene Synthesis Market Become By 2030 Compared To 2026?
The gene synthesis market has experienced substantial expansion in recent times. Projections indicate it will expand from $3.95 billion in 2025 to $4.76 billion in 2026, demonstrating a compound annual growth rate (CAGR) of 20.7%. Historically, this expansion can be linked to several factors, including developments in recombinant DNA technology, a surge in pharmaceutical research and development, the implementation of automated synthesis platforms, the proliferation of academic research institutions, and an escalating need for gene editing tools.
The gene synthesis market is projected to undergo substantial expansion in the upcoming years, with its size expected to reach $10.44 billion in 2030, exhibiting a compound annual growth rate (CAGR) of 21.7%. This anticipated growth during the forecast period is primarily driven by factors such as the increasing development of gene and cell therapies, heightened investment in synthetic biology, a rise in vaccine development initiatives, the expansion of contract research organizations, and the growing application of viral dna synthesis in diagnostics. Noteworthy trends for this period include the broadening of synthetic biology applications, the advancement of personalized gene therapies, an escalating demand for high-fidelity dna synthesis, innovations in enzyme-based synthesis techniques, and an increase in research efforts from academic institutions and government bodies.
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What Are The Main Drivers Accelerating The Growth Of The Gene Synthesis Market?
Growing demand for biofuels is anticipated to drive the expansion of the gene synthesis market. Biofuels represent a renewable energy source, originating from organic substances like plants or animal waste, serving as a substitute for conventional fossil fuels. In the creation of biofuels, gene synthesis facilitates the engineering of microorganisms, equipping them with improved metabolic pathways to efficiently transform organic materials into biofuels. An illustrative example comes from the International Energy Agency (IEA), a France-based intergovernmental organization, which reported in June 2023 that biofuel demand is forecast to increase by 6%, or 5700 million liters, from 2022 to 2024 across advanced economies. The majority of this expansion is expected in the United States and Europe. Consequently, the escalating demand for biofuels is acting as a key driver for the gene synthesis market.
Which Segment Groups Define The Gene Synthesis Market Landscape?
The gene synthesis market covered in this report is segmented –
1) By Method: Solid-Phase Synthesis, Chip-Based Synthesis, PCR-Based Enzyme Synthesis
2) By Service: Antibody DNA Synthesis, Viral DNA Synthesis, Other Services
3) By Application: Gene And Cell Therapy Development, Vaccine Development, Disease Diagnosis, Other Applications
4) By End-User: Biotechnology And Pharmaceutical Companies, Academic And Government Research Institutes, Contract Research Organizations
Subsegments:
1) By Solid-Phase Synthesis: Phosphoramidite Method, H-phosphonate Method
2) By Chip-Based Synthesis: Microarray Technology, Light-Directed Synthesis
3) By PCR-Based Enzyme Synthesis: Polymerase Chain Reaction (PCR), Reverse Transcription PCR (RT-PCR)
What Trends Are Impacting The Gene Synthesis Market?
Leading companies in the gene synthesis market are concentrating on delivering advanced platforms, such as silicon-based DNA synthesis platforms, to satisfy the need for quicker delivery and secure a competitive advantage. A silicon-based DNA synthesis platform is a technology that uses silicon wafers to facilitate the miniaturization of the chemical reactions involved in DNA creation during the gene synthesis process. For instance, in November 2023, Twist Bioscience Corporation, a US-based biotechnology company, launched Twist Express Genes, a rapid gene synthesis service with a turnaround time of five to seven business days. This service leverages a silicon-based DNA synthesis platform to meet customer expectations for faster delivery. The Express Genes service is designed to cater to researchers in both industry and academia who either purchase DNA from suppliers or synthesize genes independently, providing a comprehensive solution for their gene production requirements. GenScript, another key player, guarantees plasmid yield and 100% sequence accuracy, upholding high standards of quality and reliability in its offerings.
Which Industry Players Are Present In The Gene Synthesis Market?
Major companies operating in the gene synthesis market are Genscript Biotech Corporation, Twist Bioscience Corp., ProteoGenix Inc., Biomatik Corporation, ProMab Biotechnologies Inc., Thermo Fisher Scientific Inc., Integrated DNA Technologies Inc., OriGene Technologies Inc., GenScript Corp., Merck KGaA, Codex DNA Inc., Genewiz Inc., Eurofins Genomics LLC, BioCat GmbH, Bioneer Pacific Co. Ltd., Bio Basic Inc., Beijing SBS Genetech Co. Ltd, Creative Biogene Inc, Exonbio LLC., Trenzyme GmbH, Polygen GmbH, MACROGEN CO. LTD., Synbio Technologies LLC
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Which Area Represents The Largest Portion Of The Gene Synthesis Market?
North America was the largest region in the gene synthesis market in 2025. Asia-Pacific is expected to be the fastest-growing region in the global gene synthesis market report during the forecast period. The regions covered in the gene synthesis market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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