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How has the mtor inhibitors market grown in recent years?

The market size of mTOR inhibitors has seen robust growth in the past years. It is projected to increase from $7.43 billion in 2024 to $7.81 billion in 2025, indicating a compound annual growth rate (CAGR) of 5.2%. This substantial growth experienced in the historical period can be linked to progress in oncology therapy, renal cell carcinoma treatment, transplantation medicine, clinical studies, drug development, and applications in immunosuppression.

How is the mtor inhibitors market size expected to evolve during the forecast period?

Anticipations are high for substantial escalation in the mTOR inhibitors market in the forthcoming years. The market is projected to surge to “$9.9 billion by 2029, documenting a compound annual growth rate (CAGR) of 6.1%. This anticipated expansion during the forecast period can be linked to the enlargement of oncology indications, breakthroughs in precision medicine, a rise in transplantation instances, management of chronic diseases, and a growing aged population. Key trends expected during this period encompass exploration of neuroprotective effects, application in transplant medicine, escalating interest in metabolic disorders, partnerships for drug development, and worldwide health schemes for rare diseases.

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Which key drivers are propelling the mtor inhibitors market’s growth?

The escalating incidences of kidney ailments are projected to boost the growth of the mTOR inhibitors market. Kidney disease is a condition that progressively degrades the organs and reduces their functioning capacity. mTOR inhibitors have been instrumental in treating various kidney conditions. Preventive treatments for renal allograft rejection include immunosuppressive medications like sirolimus and everolimus, which are mTOR inhibitors. The increasing global prevalence of kidney diseases escalates the demand for mTOR inhibitors. For instance, in April 2022, the International Society of Nephrology, a professional association based in the US, reports that 843.6 million people around the world have been affected by stages 1 to 5 of kidney diseases. Over 800 million people worldwide, equivalent to 10% of the total population, are suffering from chronic renal disease, a degenerative disorder. Hence, the rising prevalence of kidney ailments is anticipated to drive the mTOR inhibitors market’s growth.

What are the market segments in the mtor inhibitors industry?

The mTOR inhibitors market covered in this report is segmented –

1) By Product Type: Rapamune, Afinitor, Torisel, Zortress, Other Product Types

2) By Indication: Oncology, Immunosuppressant, Organ Transplantation, Other Indications

3) By Route of Administration: Oral, Intravenous

4) By Application: Tumor Treatment, Kidney Transplant, Other Applications

5) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies

Subsegments:

1) By Rapamune: Dosage Forms, Indications

2) By Afinitor: Dosage Forms, Indications

3) By Torisel: Dosage Forms, Indications

4) By Zortress: Dosage Forms, Indications

5) By Other Product Types: Experimental MTOR Inhibitors, Generic Versions of MTOR Inhibitors, Combination Therapies with MTOR Inhibitors

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Which leading companies are shaping the growth of the mtor inhibitors market?

Major companies operating in the mTOR inhibitors market include Novartis AG, Pfizer Inc., Teva Pharmaceutical Industries Ltd., Hikma Pharmaceuticals plc, LC Laboratories, Exelixis Inc., Dr. Reddy’s Laboratories Ltd., Zydus Lifesciences Limited, Accord Healthcare Inc., Par Pharmaceutical, AbbVie Inc., GlaxoSmithKline plc, Biocon Limited, Alkem Laboratories Ltd., Gland Pharma Ltd., Apotex Inc., Glenmark Pharmaceuticals Ltd., AstraZeneca plc, Bristol-Myers Squibb Company, Eli Lilly and Company, Merck & Co. Inc., AmpliPhi Biosciences Corporation, Melinta Therapeutics Inc., Aduro Biotech Inc., Cumberland Pharmaceuticals Inc., Nabriva Therapeutics plc, Paratek Pharmaceuticals Inc., Bayer AG, Boehringer Ingelheim International GmbH

What key trends are currently impacting the mtor inhibitors market’s development?

The mTOR inhibitors market is seeing an increasing trend with businesses focusing on collaborations and partnerships. Aiming to gain a significant edge in the mTOR inhibitors market, various companies are entering into partnerships. For example, in October 2022, a collaboration deal was sealed between US clinical-stage oncology company, Mirati Therapeutics, Inc., and Aadi Bioscience, Inc., a US commercial stage biopharmaceutical firm committed to developing precision therapies for genetic-based cancers. The details of this collaboration remain undisclosed, but the objective is to capitalize on the combined effect of two drugs that could potentially offer augmented benefits to patients with KRAS G12C mutant NSCLC and other cancer types. Aadi Bioscience is seeking to provide treatments to cancer patients with mTOR pathway driver alterations. In another development in February 2022, Cambrian Biopharma, a US longevity biotech company with multiple assets, entered into a licensing agreement with Novartis, a Switzerland-based company specializing in oncology and other rare diseases. The details of the agreement remain undisclosed, but it aims to advance a set of innovative and specific compounds that Novartis has developed and characterized, specifically designed to target the (mTOR) pathway.

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Which geographic areas are influencing the growth of the mtor inhibitors market?

North America was the largest region in the mTOR inhibitors market in 2024.Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the mTOR inhibitors market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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