Global CAR-T Therapy Market
Medical Equipment

Exploring Key Insights of the CAR-T Therapy Market: Growth Prospects, Emerging Trends, and Opportunities

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How has the car-t therapy market size evolved in recent years?

The market size for CAR-T therapy has witnessed significant expansion in the past few years. It is projected to increase from $2.53 billion in 2024 to $3.01 billion in 2025, exhibiting a compound annual growth rate (CAGR) of 18.9%. This heightened growth during the historic period is principally due to augmented healthcare spending, rise in pharmaceutical R&D expenditure, and progression in drug discovery.

What are the predictions for the car-t therapy market size in the coming years?

In the coming years, the CAR-T therapy market size is anticipated to witness a substantial expansion. It’s projected to reach $5.42 billion in 2029, with a compounded annual growth rate (CAGR) of 15.9%. The predicted growth during this period can be ascribed to the surge in the occurrence of blood cancer, increased healthcare spending, robust pipeline of drugs, and a growing emphasis on CAR-T therapy. Key trends for this projected period comprise of investment in research and development for creating revamped CAR-T therapy to mitigate neurological side effects, crafting off-the-shelf allogeneic CAR-T therapy for advanced cancer remedies, the manufacture of next-generation CAR T cells for enhanced high-grade glioma treatment, investments in AI and machine learning solutions to refine future CAR-T therapy, executing strategic partnerships to fuel innovations, collaborating or buying out competitor businesses to broaden the CAR-T therapy portfolio, and putting more money into CAR-T therapy to increase its efficacy.

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What key factors are fueling the growth of the car-t therapy market?

The rise in the CAR-T therapy market is propelled by growing financial contributions from various institutions to encourage the growth and adoption of CAR-T therapy. To aid with the research and development of CAR-T therapy and subsidize acute lymphoblastic leukemia (ALL) treatment for patients, financial assistance is provided by both governmental and non-governmental organizations. For example, The Centers for Medicare and Medicaid Services, a federal agency based in the United States, reported a 4.1% increase in health care expenditure in 2023, totaling to $4.5 trillion, a significant jump from the 3.2% rise in 2021. Furthermore, hospital service expenses saw an increase of 2.2% in 2022, contributing to $1.4 trillion. This continued financial backing for CAR-T therapy from various organizations fuels the expansion of the CAR-T therapy market.

How is the global car-t therapy market divided into key segments?

The CAR-T therapy market covered in this report is segmented –

1) By Type: Monotherapy, Combination Therapy

2) By Target Antigen: CD19, CD22, BCMA, Other Target Antigens

3) By Application: Acute Lymphoblastic Leukemia, Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, Chronic Lymphocytic Leukemia, Multiple Myeloma, Other Applications

Subsegments:

1) By Monotherapy: CD19-targeted CAR-T Therapy, BCMA-Targeted CAR-T Therapy

2) By Combination Therapy: CAR-T Therapy With Immune Checkpoint Inhibitors, CAR-T Therapy With Other Targeted Therapies, CAR-T Therapy With Chemotherapy Or Radiotherapy

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Who are the key firms paving the way for growth in the car-t therapy market?

Major companies operating in the CAR-T therapy market include Gilead Sciences, Novartis AG, Biocon, Gracell Biotechnology Ltd, Aeon Therapeutics, CARsgen Therapeutics, Daiichi Sankyo, Otsuka Pharmaceutical, Ono Pharmaceutical, Takeda Pharmaceutical Company, Astellas Pharma, Innovative Cellular Therapeutics, Cellular Biomedicine Group, PersonGen Biomedicine, Hebei Senlang Biotech, Adaptimmune(UK), Autolus Therapeutics, BioNTech, Cellectis, Celyad, Crescendo Biologics, GammaDelta Therapeutics, Immatics, Biocad, Celgene Corporation, Johnson & Johnson, F. Hoffmann-La Roche Ltd, Eli Lilly and Company, Amgen, AstraZeneca, Bayer AG, Merck, Pfizer, Juno Therapeutics, Allogene Therapeutics, Regen BioPharma, OncoSec Medical Incorporated, Precision BioSciences, Bellicum, Sandoz AG, GlaxoSmithKline plc

Which trends are expected to transform the car-t therapy market?

Leading businesses in the CAR-T therapy market are prioritizing the creation of innovative solutions like diagnostic tools to boost individualized treatment and patient results. These diagnostic tools, whether they are instruments, devices, or software, play a crucial role in identifying and analyzing diseases in patients, thereby paving the way for more precise diagnoses and effective treatment strategies. For instance, Eurofins Viracor, a clinical diagnostic laboratory based in the US, pioneered the ExPeCT Expansion and Persistence of CAR T Assay in February 2023. This assay is instrumental in better deciphering the performance of CAR-T therapy in patients. It comes with dual advantages as it not only facilitates CAR T cell growth and persistence monitoring over time, delivering real-time data to evaluate patient care and treatment efficacy, but also holds the potential to pinpoint those at risk of treatment failure due to insufficient CAR T cell dynamics. This could lead to prompt interventions that might amplify clinical results in patients with blood cancers.

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What regions are contributing significantly to the growth of the car-t therapy market?

North America was the largest region in the CAR-T therapy market in 2024. Western Europe was the second-largest region in the global CAR-T therapy market share. The regions covered in the CAR-T Therapy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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