Comprehensive Analysis of the Hepatic Encephalopathy Market 2025-2034: Growth Rates, Trends, and Future Opportunities
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How has the Hepatic Encephalopathy market grown in recent years?
The market size for hepatic encephalopathy has seen significant expansion in the past few years. The growth is projected to rise from $1.72 billion in 2024 to $1.8 billion in 2025, marking a compound annual growth rate (CAGR) of 5.1%. The notable growth during this historic period can be credited to the rising prevalence of liver diseases, increased awareness about hepatic encephalopathy, initiatives taken by the government, and the emergence of novel liver therapies.
How is the hepatic encephalopathy market size expected to evolve during the forecast period?
Anticipated to witness robust growth in the forthcoming years, the size of the hepatic encephalopathy market is projected to expand to $2.23 billion in 2029, with a compound annual growth rate (CAGR) of 5.5%. Factors prompting this growth during the forecast period include the rising aged population, an influx of treatment options, increased healthcare infrastructure expenditure, and investments in hepatic encephalopathy treatments. Key trends for the projected period are the introduction of novel therapies, heightened research and clinical trials, advancements in liver transplantation, pharmaceutical breakthroughs, improvements in nutrition and dietary management, and the adoption of telemedicine and remote monitoring.
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Which key drivers are propelling the hepatic encephalopathy market’s growth?
The surge in liver disease cases is anticipated to further stimulate growth in the hepatic encephalopathy market. Liver disease, which is identified as a health anomaly that impacts liver function, can be managed and even moderated with treatments like hepatic encephalopathy. These treatments can mitigate symptoms, decelerate the disease’s progression, restore liver health, and decrease the onset of hepatic encephalopathy by bettering the control of underlying conditions. This could potentially decrease the frequency and intensity of the disease and boost the overall standard of living for the patients. According to data provided in April 2024 by the UK government department, Office for Health Improvement and Disparities, the rate of hospital admissions due to liver disease continued to rise, reaching a peak of 155.2 per 100,000 residents (ranging between 152.9 and 157.5) in the fiscal year ending 2023, a climb from the previous year’s 150.6 (varying from 148.2 to 152.9). Consequently, the escalating prevalence of liver disease is driving the growth of the hepatic encephalopathy market. In view of the Hepatic Encephalopathy Market Driver: the growth of the hepatic encephalopathy market is predicted to be driven by the rise in healthcare expenditures. The term ‘healthcare expenditures’ points to the cumulative cost involved in health-related services, goods, and activities over a given time period. This generally pertains to expenses on an individual, community, national, or worldwide scale. Heightened healthcare expenditure can contribute towards the positive development of hepatic encephalopathy treatment methodologies by fostering progress in diagnostics, treatment procedures, awareness, and patient care. According to data released in December 2023 by the US federal agency, Centers for Medicare & Medicaid Services, there was a 4.1% increase in U.S. health care spending in 2022, taking the total to $4.5 trillion. This is greater than the preceding year’s growth rate of 3.2%. Therefore, the hike in healthcare expenditure will fuel the growth of the hepatic encephalopathy market.
What are the market segments in the hepatic encephalopathy industry?
The hepatic encephalopathy market covered in this report is segmented –
1) By Drug Class: Antibiotics, Laxatives, L-Ornithine, L-Aspartate, Other Drug Classes
2) By Route Of Administration: Oral, Intravenous, Rectal
3) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies
Subsegments:
1) By Antibiotics: Rifaximin, Neomycin, Metronidazole
2) By Laxatives: Lactulose, Polyethylene Glycol, Sorbitol
3) By L-Ornithine, L-Aspartate: L-Ornithine L-Aspartate
4) By Other Drug Classes: Zinc Supplements, Probiotics, Hepatoprotective Agents
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Which leading companies are shaping the growth of the hepatic encephalopathy market?
Major companies operating in the hepatic encephalopathy market are Umecrine Cognition AB, Bausch Health Companies Inc., Mallinckrodt Pharmaceuticals, Lupin Limited, Salix Pharmaceuticals, Norgine B.V., Ferring B.V., ASKA Pharmaceutical Co. Ltd., Vedanta Biosciences Inc., Gilead Sciences Inc., Amgen Inc., Teva Pharmaceutical Industries Ltd., Mylan N.V., Bausch Health Companies Inc., Ochsner Health Inc., Sun Pharmaceutical Industries Ltd., Dr. Reddy’s Laboratories Ltd., Cipla Limited, Amneal Pharmaceuticals LLC, Mallinckrodt PLC, Lupin Limited, Torrent Pharmaceuticals Ltd., Salix Pharmaceuticals Inc., ASKA Pharmaceutical Co. Ltd., Norgine B.V.
What key trends are currently impacting the hepatic encephalopathy market’s development?
Key players in the hepatic encephalopathy market are stepping up the game by creating unique drugs as a treatment for hepatic encephalopathy, aiming to gain a competitive edge and solidify their market standing. For instance, in June 2023, Karolinska Development AB, a pharmaceutical firm based out of Sweden, introduced a groundbreaking drug, GR3027 (golexanolone), specifically meant for the treatment of hepatic encephalopathy. It is an orally taken small molecule and serves as a GABAA-receptor-modulating steroid antagonist (GAMSA) that aims to counterbalance any positive GABAA-receptor modulation caused by endogenous neuroactive steroids. Furthermore, the drug is currently undergoing trials for its potential use in HE. These trials are being carried out for CHE in Phases I/IIa.
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Which geographic areas are influencing the growth of the hepatic encephalopathy market?
North America was the largest region in the hepatic encephalopathy market in 2024. The regions covered in hepatic encephalopathy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
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