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How has the HERG Screening market grown over the years?

In recent times, the HERG screening market has seen substantial growth. The market, which is predicted to rise from $1.62 billion in 2024 to $1.84 billion in 2025, will witness a compound annual growth rate (CAGR) of 13.9%. The previous growth seen can be credited to the heightened drug development activities, enforcement of regulatory guidelines, a surge in cardiac safety awareness, and an increase in the number of cardiac disorders.

What Is the forecasted market size and growth rate for the herg screening market?

The market size for HERG screening is projected to experience substantial expansion in the ensuing years, with expectations of reaching $2.9 billion in 2029 at a compound annual growth rate (CAGR) of 12.0%. The escalation throughout the forecast period can be accredited to the development of personalized medicine, the rise in outsourcing of drug development procedures, the emergence of new markets and research, and emphasis on non-cardiac safety evaluations. Principal trends during the forecast period encompass advanced in vitro models, the incorporation of genomic and proteomic data, advancements in computational methods, focusing on the safety of pediatric drugs, and alliances for data sharing and standardization.

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What are the major factors driving growth in the herg screening market?

The burgeoning number of individuals suffering from heart conditions is anticipated to drive the expansion of the HERG screening market. Heart diseases, also referred to as cardiovascular disorders, encompass a variety of ailments that impact the heart and blood vessels. This can interfere with the heart’s optimal functioning and could result in severe health issues. Factors that contribute to these disorders include unhealthy lifestyles, an aging population, genetic predispositions, diabetes, and metabolic syndrome. HERG screening serves to detect potential drug candidates and prevent serious cardiac incidents that might trigger fatal cardiac arrhythmias, specifically torsade de pointes (TdP), thereby enhancing patient outcomes. For example, a report released by the US-based Centers for Disease Control and Prevention in May 2023 revealed that 1 out of 20 adults over the age of 20 suffer from cardiovascular disorders, accounting for 695,000 individuals, with 375,476 fatalities due to these diseases. Moreover, in March 2022, a report from the UK-based Office for National Statistics revealed that 20,061 individuals succumbed to heart attacks, showing an upward trend from the previous year. As such, the growing prevalence of patients with heart disorders is a significant factor in the escalating growth of the HERG screening market.

What key areas define the segmentation of the global herg screening Market?

The HERG screening market covered in this report is segmented –

1) By Type: Gene KCNH2, Mutant KCNH2

2) By Ion Channel: Voltage-Gated, Ligand Gated

3) By Applications: Antiarrhythmic, Antipsychotic, Antibiotics, Other Applications

Subsegmeents:

1) By Gene KCNH2: Wild-Type KCNH2, Recombinant KCNH2

2) By Mutant KCNH2: Mutations: Missense Mutations, Nonsense Mutations, Frameshift Mutations

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What are the top market players propelling the growth of the herg screening industry?

Major companies operating in the HERG screening market are Eurofins-Cerep SA., Aviva Biosciences Inc., AstraZeneca Public Limited Company, Merck KGaA, Charles River Laboratories Inc., Abcam Public Limited Company, Molecular Devices LLC, Caliper Life Sciences Inc., Crprotex Limited, ChanTest Corporation, Creative bioarray Inc., Cellular Dynamics International Inc., Nanion Technologies, Essen Bioscience, ABR-Affinity BioReagents Inc., ACEA Biosciences Inc., Metrion biosciences Inc., Aurora Biomed Inc., Aureus Sciences, RedShift BioAnalytics, B’SYS GmbH, Cambridge Bioscience Ltd., Sophion Bioscience Inc., Fluxion Biosciences Inc., ChemAxon Ltd.

What are the key trends shaping the future of the herg screening market?

Leading firms in the HERG screening market are focusing on pioneering novel, sophisticated solutions like GLP-certified HERG screening services to improve cardiac safety evaluations during drug development phases. This involves the utilisation of the standard whole-cell patch-clamp process for good laboratory practice-certified screening of the human ether-à-go-go related gene (hERG), ensuring adherence to regulatory standards like ICH S7A and ICH S7B – vital for safety pharmacology studies within drug creation. As an illustration, in August 2023, the UK pharmaceutical organization, Metrion Biosciences Ltd., unveiled the GLP-certified hERG screening service. This service is designed to boost Metrion’s contribution to small-molecule therapeutic creation and augment the firm’s existing cardiac safety service range. Moreover, this service employs the standard whole-cell patch-clamp method to anticipate possible cardiac risks prior to the initiation of Phase 1 clinical trials on human subjects, provides regulatory advice for safety pharmacology studies during drug development, and presents clients with superior-quality biology services concerning ion channel targets.

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What regions are dominating the herg screening market growth?

North America was the largest region in the HERG screening market in 2024. Asia-Pacific is expected to be the fastest growing region in the forecast period. The regions covered in the HERG screening market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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