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How has the inherited retinal disease market grown over the years?

The market size for inherited retinal disease has shown significant growth in the past years. An increase from $11.56 billion in 2024 to $12.58 billion in 2025, with a compound annual growth rate (CAGR) of 8.8%, is projected. The growth witnessed in the historic era is the result of acceptance of gene therapy, regulatory rewards, expansion in patient registries, surge in clinical trials, and development in patient-focused solutions.

What Is the forecasted market size and growth rate for the inherited retinal disease market?

The market size of the inherited retinal disease industry is projected to experience robust growth in the upcoming years. By 2029, it is anticipated to reach $17.42 billion with a compound annual growth rate (CAGR) of 8.5%. Factors contributing to this growth during the prediction period include the increased utilization of CRISPR, the rise of individualized therapy, emphasis on regenerative medicine, patient advocacy expansion, and dedication to enhancing patient quality of life. Key trends anticipated during this period include the progression in optogenetics technology, the innovation of artificial retina implants, growth in digital health platforms, implementation of artificial intelligence in disease modelling, and the application of artificial intelligence in devising treatment plans.

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What are the major factors driving growth in the inherited retinal disease market?

The expected rise in macular degeneration cases is forecasted to fuel the expansion of the inherited retinal disease market in the future. Macular degeneration is a condition associated with aging that wreaks havoc on the macula, resulting in loss of central vision and hindering tasks such as reading or identifying faces. This rise in macular degeneration is catalyzed by factors like aging demographics, increased life expectancy, and lifestyle choices such as smoking and bad nutrition, which escalate risk. Treatment for inherited retinal disease aids those suffering from macular degeneration by zeroing in on the genetic roots of retinal degeneration, offering therapies that slow down the course of the disease, restore lost vision, or even stave off additional damage to the retina. These treatments ultimately enhance visual outcomes and elevate the quality of life for those affected by macular degeneration related to age or inheritance. For example, in February 2024, as reported by the Canadian Ophthalmological Society, a nonprofit organization in Canada, it was discovered that 2.5 million Canadians aged 55 and over lose their vision due to age-related macular degeneration (AMD). Consequently, the escalating prevalence of macular degeneration is steering the inherited retinal disease market’s growth.

What key areas define the segmentation of the global inherited retinal disease Market?

The inherited retinal disease market covered in this report is segmented –

1) By Type: Diagnosis, Therapy

2) By Disease Type: Retinitis Pigmentosa, Choroideremia, Stargardt Disease, Cone-rode Dystrophy, Leber Congenital Amaurosis, Other Diseases

3) By Distribution Channel: Retail Sales, Direct Tender

4) By End Users: Hospitals, Speciality Clinics, Ambulatory Surgical Centres, Home Healthcare, Other End Users

Subsegments,

1) By Diagnosis: Genetic Testing (Genetic Screening), Retinal Imaging (Fundus Photography, Optical Coherence Tomography (OCT)), Electrophysiological Testing (Electroretinography), Visual Field Testing, Fundus Autofluorescence Imaging

2) By Therapy: Gene Therapy, Stem Cell Therapy, Retinal Prosthesis (Artificial Retina), Pharmacological Therapy (Gene Editing, Retinal Drugs), Photoreceptor Rescue Therapy

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What are the top market players propelling the growth of the inherited retinal disease industry?

Major companies operating in the inherited retinal disease market are Johnson & Johnson, Novartis AG, Astellas Pharma Inc., Biogen Inc., Vertex Pharmaceuticals Inc., Ionis Pharmaceuticals Inc., Invitae Corporation, Spark Therapeutics, Aldeyra Therapeutics, Regenxbio Inc., IVERIC bio, MeiraGTx Limited, Ocugen Inc., Coave Therapeutics, Bionic Vision Technologies, GenSight Biologics SA, LKC Technologies Inc., Sparing Vision, ProQR Therapeutics NV, Endogena Therapeutics

What are the key trends shaping the future of the inherited retinal disease market?

Major companies operating in the inherited retinal diseases market focus on developing innovative therapies, such as mutation-agnostic gene therapy, to provide inclusive treatment options and address a wider range of genetic variations associated with these conditions. Mutation-agnostic gene therapy is a treatment approach targeting broader genetic mechanisms or pathways, rather than specific mutations, making it applicable to diverse genetic disorders. For instance, in March 2024, Nanoscope Therapeutics Inc, a US-based biotechnology company, announced positive results of a clinical trial of its lead program, MCO-010, which demonstrates vision improvements for patients with permanent and severe vision loss from advanced retinitis pigmentosa. MCO-010 achieved its primary and key secondary endpoints with statistical significance and no serious adverse events.

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What regions are dominating the inherited retinal disease market growth?

North America was the largest region in the inherited retinal disease market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the inherited retinal disease market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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