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How has the ultomiris market grown over the years?

Recent years have seen the market size for ultomiris grow at an XX (HCAGR). Projected growth is from $XX million in 2024 to $XX million in 2025, boasting a compound annual growth rate (CAGR) of XX%. The substantial growth during the historic period is a product of the increasing occurrences of chronic ailments, a growing need for biologics, expanded usage of mAb therapies, a rising incidence of autoimmune diseases and an escalated occurrence of PNH.

What Is the forecasted market size and growth rate for the ultomiris market?

Anticipations suggest a noticeable increase, in terms of XX (FCAGR), in the market size of Ultomiris in the upcoming years. The market projection for Ultomiris shows that it will upscale to $XX million by 2029 with an XX% compound annual growth rate (CAGR). Much of this anticipated growth during the forecast period can be accredited to the growing pressure on healthcare systems, escalating instances of arthritis and inflammatory conditions, amplified investments in scientific research, an upward curve in drug approvals, and a rising incidence rate of musculoskeletal disorders. The forecast period also points towards major trends like improved hospital structure, advancements in therapeutic options, strategic partnerships for research, production of orphan drugs, and expansion into new disease areas.

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What are the major factors driving growth in the ultomiris market?

The growth of the ultomiris market is expected to be fueled by the rising incidence rate of autoimmune diseases. This term refers to a group of diseases where the body’s immune system mistakenly incites an attack on its own healthy cells and tissues. Increased exposure to environmental pollutants and chemicals, in combination with enhanced diagnostic capabilities, are key contributors to this rising incidence of these diseases, as these factors have facilitated the identification and treatment of more people. Autoimmune diseases like Paroxysmal Nocturnal Hemoglobinuria (PNH) and Atypical Hemolytic Uremic Syndrome (aHUS) are treated with ultomiris, which works by inhibiting the complement protein C5, thereby decreasing the immune system’s attacks on the body. The Australian Institute of Health and Welfare, a governmental body based in Australia, reported in June 2024 that there were 10,000 hospitalizations due to rheumatoid arthritis, an autoimmune disease, in 2022. This represented a 25% increase from 8,000 the prior year, and a hospitalization rate of 39 per 100,000 individuals. Hence, the rising incidence of autoimmune diseases is fueling the growth of the ultomiris market.

What key areas define the segmentation of the global ultomiris Market?

The ultomiris market covered in this report is segmented –

1) By Indication: Paroxysmal Nocturnal Hemoglobinuria (PNH); Atypical Hemolytic Uremic Syndrome (aHUS); Generalized Myasthenia Gravis (gMG); Neuromyelitis Optica Spectrum Disorder (NMOSD)

2) By Formulation: Intravenous Solution; Subcutaneous Formulation

3) By Distribution Channel: Hospital And Clinics; Retail And Specialty Pharmacies

4) By End User: Adult Patients; Pediatric Patients

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What are the top market players propelling the growth of the ultomiris industry?

Major companies operating in the ultomiris market are AstraZeneca Plc.

What are the key trends shaping the future of the ultomiris market?

An important trend in the Ultomiris market involves obtaining drug approval from concerned regulatory bodies to widen its therapeutic applications and enhance market penetration. Regulatory authorities undertake the approval of new drugs for sale and use, which confirms their safety, efficacy, and quality, based on data from clinical trials. To illustrate, in March 2024, UK-based pharmaceutical company, AstraZeneca, achieved Food and Drug Administration (FDA) approval for ULTOMIRIS (ravulizumab-cwvz) to treat adults with neuromyelitis optica spectrum disorder (NMOSD) who respond positively to the anti-aquaporin-4 (AQP4) antibody. This milestone is notable, as ULTOMIRIS is the pioneering long-lasting C5 complement inhibitor for NMOSD, proving its efficacy by reducing relapse risk by 98.6% in clinical trials. Ultomiris works by preventing immune system attacks on the central nervous system through the inhibition of the complement system. Nonetheless, it carries potential risks, including serious meningococcal infections, and common side effects such as headaches and urinary tract infections.

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What regions are dominating the ultomiris market growth?

North America was the largest region in the ultomiris market in 2024. The regions covered in the ultomiris market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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