2025 Market Reports Update: Market Size Forecasts to 2034, Key Trends, Leading Players, and Top Regions – Get Ahead of the Competition Today!

What Major Innovations Are Driving the Accelerated Growth of the In Situ Hybridization Market?

The surge in infectious diseases is anticipated to stimulate the expansion of the in-situ hybridization market. These diseases are conditions that can be transmitted from one person to another via contaminated food and drinks and via microorganisms such as viruses, bacteria, fungi, and parasites. In-situ hybridization (ISH) uses labeled nucleic acid sequences or probes specific to the infectious organism to identify matching nucleic acid sequences within the tissue, thus a rise in infectious diseases spurs the in-situ hybridization market growth. For instance, in March 2024, the US-based government agency, Centers for Disease Control and Prevention, reported an increase in tuberculosis cases from 8,320 in 2022 to 9,615 in 2023, indicating a surge of 1,295 cases. Consequently, the escalating rates of infectious diseases are fueling the expansion of the in-situ hybridization market.

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#What is the Anticipated CAGR of theIn Situ Hybridization Market, and What Factors Will Drive It?

The market size for in situ hybridization has experienced substantial growth of late. The market will expand from $1.68 billion in 2024 to $1.83 billion in 2025, with a compound annual growth rate (CAGR) of 8.9%. This historical growth can be linked to its early application in research, the progression of molecular biology tools, the evolution of diagnostic applications, a systemic shift in the focal point of biomedical research, and an uptick in investment in biotechnology.

The market for in situ hybridization is anticipating swift expansion in the upcoming years, with its size projected to reach $2.79 billion in 2029, growing at a compound annual growth rate (CAGR) of 11.2%. Several factors, including higher incorporation in clinical diagnostics, growth in research and development funding, automated and high-throughput solutions, as well as broadened uses in neuroscience and pathology can account for this growth during the forecast period. Other contributing trends foresee improvements in molecular biology, an upswing in demand for research applications, expansion of diagnostic applications, a growing need for personalized medicine, and enhanced funding in biomedical research.

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What Are the Most Significant Market Trends Transforming theIn Situ Hybridization Market?

The primary players in the in situ hybridization market are focusing their resources on building cutting-edge solutions like RNA detection assays, with the hope of propelling growth in the gene therapy niche. RNA detection assays are molecular methods employed to detect and measure the presence of specific RNA molecules in a given sample. This aids in research related to gene expression, viral infections, and other phenomena related to RNA. For example, Bio-Techne Corporation, a Life Sciences company based in the United States, launched its RNAscope Plus smRNA-RNA detection assay in January 2023. This advanced in situ hybridization instrument enables concurrent fluorescent detection of tiny regulatory RNAs, like microRNAs, and three target RNAs or RNA biomarkers within the same tissue section. Offering both single-cell and subcellular resolution, this assay empowers researchers to accurately evaluate the biodistribution and effectiveness of novel gene therapies and endogenous regulatory RNAs. The assay is scalable for larger studies and is compatible with the Leica Bond Rx platform or can be used as a manual procedure. By amalgamating proprietary RNAscope and miRNAscope technologies, this assay significantly progresses our understanding of gene expression and cellular responses, providing crucial information for creating personalized gene therapies for hereditary or acquired diseases.

What Are the Top Market Players Propelling the Growth of theIn Situ Hybridization Industry?

Major companies operating in the in situ hybridization market include Thermo Fisher Scientific Inc., Bio SB Inc., BioGenex Laboratories, Advanced Cell Diagnostics Inc., Exiqon A/S, Agilent Technologies Inc., F. Hoffmann-La Roche AG, Abbott Laboratories Inc., Merck KGaA, PerkinElmer Inc., Biocare Medical LLC, Genemed Biotechnologies, Danaher Corporation, Leica Biosystems Nussloch GmbH, Bio-Rad Laboratories Inc., Oxford Gene Technology, Abnova Corporation, Qiagen, Bio-Techne Corporation, Biochain Institute Inc., Cytocell Ltd., Enzo Life Sciences Inc., Eurofins Scientific SE, FISH Technologies Sdn Bhd, Genetix Biotech Asia Pvt. Ltd., Zytomed System GmbH, Akoya Biosciences Inc., Becton Dickinson and Company (BD), DAKO Systemtechnik und Service GmbH & Co, Molecular Devices LLC., NanoString Technologies Inc., Visiopharm A/S

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Which Primary Segments of the In Situ Hybridization Market Are Driving Growth and Industry Transformations?

The in situ hybridization market covered in this report is segmented –

1) By Product: Analytical Instruments, Kits and Reagents, Software and Services, Other Products

2) By Technique: Fluorescence In Situ Hybridization (FISH), Chromogenic In Situ hybridization (CISH)

3) By Probe: Deoxyribonucleic Acid (DNA), Ribonucleic Acid (RNA)

4) By Application: Cancer, Cytogenetics, Developmental Biology, Infectious Diseases, Other Applications

5) By End Use: Research And Diagnostic Laboratories, Contract Research Organization (CROs), Academic Institutes, Other End Uses

Subsegments:

1) By Analytical Instruments: Fluorescence Microscopes, Imaging Systems, Hybridization Systems

2) By Kits and Reagents: Hybridization Kits, Detection Kits, Probes And Reagents

3) By Software and Services: Image Analysis Software, Data Management Software, Consulting And Support Services

4) By Other Products: Accessories, Control Samples, Maintenance Supplies

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Which Regions Are Key Players in the Growth of the #What Major Innovations Are Driving the Accelerated Growth of the In Situ Hybridization Market?# Market?

North America was the largest region in the in situ hybridization market in 2024. Asia-Pacific is expected to be the fastest-growing region in the global in situ hybridization market during the forecast period. The regions covered in the in situ hybridization market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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