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Unlocking Opportunities in the Oncolytic Virus Therapy Market: Key Trends, Market Growth, and Forecast Insights

2025 Market Reports Update: Market Size Forecasts to 2034, Key Trends, Leading Players, and Top Regions – Get Ahead of the Competition Today!

What Factors Are Propelling the Market Growth of the Oncolytic Virus Therapy Market from 2025 to 2034?

The upswing in the occurrences of cancer is anticipated to fuel the expansion of the oncolytic virus therapy market in the future. The term ‘cancer’ signifies a collection of diseases marked by the unchecked multiplication and dissemination of abnormal cells within the body. Oncolytic virus therapy carries the promising capacity to specifically target and eradicate cancer cells, simultaneously inducing an immune response against the tumor, thus providing an effective two-pronged approach for treating cancer. For example, the American Cancer Society Inc., a non-profit entity based in the US, predicts that in January 2023, there will be roughly 609,820 mortalities and 1,958,310 new diagnoses of cancer within the US during 2022. Consequently, the escalating instances of cancer are augmenting the growth of the oncolytic virus therapy market.

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What is the Predicted Annual Growth Rate of the Oncolytic Virus Therapy Market Impact Industry Trends by 2034?

The market size of oncolytic virus therapy has seen a sharp increase in the last few years. It is projected to escalate from $0.19 billion in 2024 to $0.23 billion in 2025, marking a compound annual growth rate (CAGR) of 25.4%. The expansion during the historic period is linked to the advancement in genetic engineering methods, a deeper insight into the tumor microenvironment, successes in the clinical field and approval from regulatory bodies, the growing prominence of immunotherapy in treating cancer, and the progress in gene delivery systems.

The market for oncolytic virus therapy is predicted to witness robust growth over the next years, expanding to $0.55 billion by 2029 with a 23.7% CAGR. The forecasted growth can be linked to the broadening of oncolytic virus platforms, the pairing of therapies with immune checkpoint inhibitors, the adoption of personalized medicine strategies, expanded clinical trial fields, and support from regulations and guidelines. Noteworthy trends during this forecast period include the progression of delivery system technology, advancements in synthetic biology, increased collaboration and partnerships in the biopharmaceutical sector, virology and immunology breakthroughs, and an emphasis on pediatric oncology.

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How Are Market Trends and Innovations Revolutionizing the Oncolytic Virus Therapy Industry in Recent Times?

Leading organizations in the oncolytic virus therapy market are focusing on acquiring regulatory authorizations in order to speed up the launch of innovative cancer treatments. These regulatory permissions are the evaluation and approval processes carried out by health regulators for the commercial use of medical products, such as drugs, biologics, and healthcare devices. For instance, ImmVira, a biotech firm based in China, was granted a Fast Track status by the FDA for its MVR-T3011 IT, an oncolytic virus therapy in March 2024. This treatment is aimed at addressing recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) in patients who’ve seen disease progression after platinum-based chemotherapy and at least one previous anti-PD-1/PD-L1 therapy. Such Fast Track designation is aimed at accelerating the development and review of treatments for serious diseases having unfulfilled medical requirements.

Which Key Market Players Are Shaping the Future and Growth of theOncolytic Virus Therapy Market?

Major companies operating in the oncolytic virus therapy market include Pfizer Inc., Johnson & Johnson, Sorrento Therapeutics Inc., AbbVie Inc., AstraZeneca plc, Amgen Inc., Boehringer Ingelheim Group, Regeneron Pharmaceuticals, Daiichi Sankyo Company Limited, Kissei Pharmaceutical Co. Ltd., Takara Bio Inc., Oncorus Inc., Replimune Inc., Vyriad Inc., Genelux Corporation, Oncolys BioPharma Inc., Adze Biotechnology, Oncolytics Biotech Inc., TILT Biotherapeutics Ltd., Transgene SA, Circio Holding ASA, Lokon Pharma AB, Provectus Biopharmaceuticals Inc., Vibalogics

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The oncolytic virus therapy market covered in this report is segmented –

1) By Therapy Type: HSV-Based Oncolytic Virus Therapy, Adenovirus-Based Oncolytic Virus Therapy, Reovirus, Poxviruses, NDV (Newcastle Disease Virus), Other Therapy Types

2) By Virus Type: Genetically Engineered Oncolytic Viruses, Oncolytic Wild-Type Viruses

3) By Application: Breast Cancer, Lung Cancer, Prostate Cancer, Melanoma, Brain Tumor, Blood Cancer

4) By End-User: Hospitals, Specialty Clinics, Cancer Research Institutes

Subsegments:

1) By HSV-Based Oncolytic Virus Therapy: Talimogene Laherparepvec (T-VEC), Other HSV-Based Therapies

2) By Adenovirus-Based Oncolytic Virus Therapy: Onyx-015, AdV-5/3-D24, Other Adenovirus-Based Therapies

3) By Reovirus: Reolysin, Other Reovirus Therapies

4) By Poxviruses: JX-594 (OncoVac), Other Poxvirus Therapies

5) By NDV (Newcastle Disease Virus): NDV-Based Therapies, Other NDV Applications

6) By Other Therapy Types: Combination Therapies, Other Emerging Oncolytic Virus Therapies

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What Regions Are Dominating the Oncolytic Virus Therapy Market Growth?

North America was the largest region in the oncolytic virus therapy market in 2024 and is expected to be the fastest-growing region in the forecast period. The regions covered in the oncolytic virus therapy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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