Oligonucleotide Therapy Market 2025-2034: Key Highlights, Growth Dynamics, and Emerging Trends
2025 Market Reports Update: Market Size Forecasts to 2034, Key Trends, Leading Players, and Top Regions – Get Ahead of the Competition Today!
How Are Key Drivers Contributing to the Growth and Expansion of the Oligonucleotide Therapy Market?
The global increase in cancer cases is expected to fuel the growth of the oligonucleotide therapy market in the forecast period. As per the American Cancer Society’s data from January 2022, it is projected that there will be 1.9 million new cancer diagnoses and 609,360 cancer-induced deaths in the US, amounting to approximately 1,670 deaths each day. Lung, prostate, bowel, and female breast cancer are the four most prevalent cancers worldwide, making up 43% of all new cancer diagnoses. Consequently, the worldwide surge in cancer incidence rates is predicted to stimulate the demand for the oligonucleotide therapy market in the coming years.
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#How Does the ProjectedOligonucleotide Therapy Market Growth Compare Over the Forecast Period?
The market size for oligonucleotide therapy has seen significant expansion in recent times. The market, valued at $5.55 billion in 2024, is expected to inflate to $6.18 billion in 2025, exhibiting a compound annual growth rate (CAGR) of about 11.4%. Created through factors such as increased funds for research and development, the inception of early treatments, advancements in gene-editing methods, and the surfacing of early therapeutic studies and the introduction of RNai and antisense oligonucleotide, this historic period growth is noteworthy.
The market size for oligonucleotide therapy is projected to experience a swift rise in the forthcoming years. It’s predicted to escalate to a value of $9.82 billion in 2029, with a compound annual growth rate (CAGR) of 12.3%. This growth within the forecast period is expected due to factors such as an increase in research and development funding, penetration of global markets, expansion of therapeutic areas, incorporating disease altering tactics, and regulatory changes. In the forecast period, key trends to look out for include personalised treatment approaches, developments in delivery systems, advances in rna interference (RNAI), innovation of antisense oligonucleotide, and inclusion of gene-editing techniques.
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What New Market Trends Are Reshaping theOligonucleotide Therapy Market and Its Opportunities?
Key players in the oligonucleotide therapy market are channeling investments into R&D to ameliorate the therapy’s design to lower its impacts on patients. With the latest and groundbreaking oligonucleotides, precision medicine is made possible and they can be customized to target any gene with negligible side effects. Additionally, they assist in pinpointing patient-specific sequences that lead to rare diseases. In the month of April 2023, the FDA gave its seal of approval to Qalsody, a type of antisense oligonucleotide (ASO), specifically for treating patients suffering from amyotrophic lateral sclerosis (ALS) linked to a mutation in the superoxide dismutase 1 (SOD1) gene. The role of Qalsody is to target SOD1 mRNA to curtail the production of SOD1 protein.
Who Are the Leading Market Players Fueling Growth in the Oligonucleotide Therapy Market Trend?
Major companies operating in the oligonucleotide therapy market include Pfizer Inc., Merck & Co. Inc., GlaxoSmithKline plc, Gilead Sciences Inc., BioNTech SE, Moderna Inc., Biogen Inc., Jazz Pharmaceuticals plc, QIAGEN Company, Alnylam Pharmaceuticals Inc., Sarepta Therapeutics Inc., Ionis Pharmaceuticals Inc., Akcea Therapeutics Inc., Arrowhead Pharmaceuticals Inc., Dicerna Pharmaceuticals Inc., SomaGenics Inc., Wave Life Sciences Ltd., Exicure Inc., Avidity Biosciences Inc., Miragen Therapeutics Inc., ProQR Therapeutics NV, Regulus Therapeutics Inc., Kastle Therapeutics LLC, Santaris Pharma A/S, InteRNA Technologies B.V., Dynacure S.A., Arcturus Therapeutics Holdings Inc., Intellia Therapeutics Inc., Regeneron Pharmaceuticals Inc., Editas Medicine Inc., Evox Therapeutics Ltd., PepGen Ltd.
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How is the Global Oligonucleotide Therapy Market Segemented?
The oligonucleotide therapy market covered in this report is segmented –
1) By Type: Antisense Oligonucleotide, Aptamer, Other Types
2) By Application: Infectious Diseases, Oncology, Neurodegenerative Disorders, Cardiovascular Diseases, Kidney Diseases, Other End-User
3) By End User: Hospitals, Research Institutes
Subsegments:
1) By Antisense Oligonucleotide: RNA-Targeted Antisense Oligonucleotides, DNA-Targeted Antisense Oligonucleotides, Chemically Modified Antisense Oligonucleotides
2) By Aptamer: DNA Aptamers, RNA Aptamers, Small Molecule Aptamers
3) By Other Types: siRNA (Small Interfering RNA), miRNA (Micro RNA), DNAzyme And Ribozymes, Synthetic Oligonucleotides For Gene Editing
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Which Geographics are Influencing the Growth of the Oligonucleotide Therapy Market?
North America was the largest region in the oligonucleotide therapy market in 2024. The regions covered in the oligonucleotide therapy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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