Denosumab Market Insights: In-Depth Look at Growth Trends, Market Size, and Opportunities for 2025-2034
2025 Market Reports Update: Market Size Forecasts to 2034, Key Trends, Leading Players, and Top Regions – Get Ahead of the Competition Today!
What External and Internal Drivers Are Contributing to the Growth of theDenosumab Market?
The denosumab market is set to experience growth due to the rising instances of osteoporosis. This medical condition, which weakens bones and increases the risk of fractures due to loss of bone density, is effectively treated with denosumab which targets RANK ligand to halt bone resorption. To illustrate, stats from the Canadian Longitudinal Study on Aging, reported by the National Center for Biotechnology Information, a US government agency in September 2023, showcased a 12.7% prevalence of osteoporosis with a physician’s diagnosis while osteoporosis confirmed through DXA stood at 5.9% among older adults living in the community. Furthermore, a study led by Buttros highlighted that out of postmenopausal women aged 40 to 75, 24.6% were diagnosed with osteoporosis after assessing bone mineral density (BMD) measurements. Hence, as the incidents of osteoporosis increase, it fuels the growth of the denosumab market.
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#What Growth Opportunities Will Drive the Denosumab Market’s CAGR Through 2034?
The market size of denosumab has witnessed a quick expansion in the past years. Its growth is projected to rise from $3.27 billion in 2024 to an impressive $3.7 billion in 2025, marking a compound annual growth rate (CAGR) of 13.1%. The notable increase during the historic period is due to valuable clinical trials and research developments, successful FDA approvals and regulatory achievements, amplified consciousness about bone health, along with strategic collaborations and marketing endeavors.
Anticipated expansion is expected in the denosumab market in the upcoming years, reaching a notable $5.59 billion by 2029, with a compound annual growth rate (CAGR) of 10.9%. Factors contributing to this growth during the forecast period include the escalating incidence of bone metastases, progress in cancer treatment methods, prevalent osteoporosis, heightened osteoporosis awareness, and regulatory acceptance for new indications. Key trends for the same period will be strategic alliances and collaborations, integration with digital health solutions, broader indications and clinical applications, and advancements in the development of biosimilars.
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Which Upcoming Market Trends and Innovations Are Set to Influence theDenosumab Market’s Path Forward?
Primary businesses in the denosumab market are intensifying their efforts to develop novel solutions like first-line osteoporosis treatments to establish an upper hand in the industry. A first-line treatment for osteoporosis is the preliminary procedure suggested by healthcare practitioners for individuals with an osteoporosis diagnosis. For example, in November 2022, China’s Boan Biotech received approval from the National Medical Products Administration (NMPA) for its denosumab biosimilar, Boyoubei, making it the pioneer Chinese company to create a denosumab injection. The company is also venturing into markets outside China, such as Europe and the US, with a global marketing strategy. Several treatment guidelines consider the drug as a primary treatment for osteoporosis. The treatment holds significant promise in reducing the likelihood of hip, non-vertebral, and vertebral fractures among patients. Moreover, Boyoubei is the first biosimilar to Prolia (the original denosumab) to gain approval for global marketing.
Who Are the Dominant Market Players Pushing the Boundaries of theDenosumab Market?
Major companies operating in the denosumab market report are Johnson & Johnson, F. Hoffmann-La Roche Ltd., Novartis International AG, Sanofi SA, GlaxoSmithKline plc, Eli Lilly and Company, Amgen Inc., Asahi Kasei Corporation, Teva Pharmaceutical Industries Ltd., Astellas Pharma Inc., Daiichi Sankyo Company, Limited, Mylan N.V., Sandoz International GmbH, Daiichi Sankyo Company Limited, Aurobindo Pharma Limited, Cipla Limited, Dr. Reddy’s Laboratories Ltd., Hikma Pharmaceuticals PLC, Celltrion Inc., Amneal Pharmaceuticals Inc, Cadila Healthcare Limited, Lupin Limited, Biocon Limited, Torrent Pharmaceuticals Ltd., Jubilant Life Sciences Limited, Ajanta Pharma Limited
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What Are the Core Segments of the Denosumab Market, and How Do They Contribute to Growth?
The denosumab market covered in this report is segmented –
1) By Drug Classification: Prolia, Xgeva, Others
2) By Type: 60 mg, 120 mg
3) By End-Users: Hospitals, Homecare, Specialty Clinics, Ambulatory Surgical Centers
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What Regions Are Dominating the Denosumab Market Growth?
North America was the largest region in the denosumab market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the denosumab market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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