Discover trends, market shifts, and competitive outlooks for the cartilage degeneration industry through 2025-2034 with The Business Research Company’s reliable data and in-depth research

How Has The Cartilage Degeneration Market Growth Evolved From 2024 To 2025, And What’s Ahead?

The market size for cartilage degeneration has seen impressive growth in the recent past. The market, valued at $12.63 billion in 2024, is projected to expand to $13.4 billion in 2025, showcasing a compound annual growth rate (CAGR) of 6.2%. Key factors driving growth during the historical period include an aging population, joint injuries, the obesity crisis, sports-related injuries, and a lack of self-repair capacity.

The market for cartilage degeneration is predicted to experience substantial expansion in the upcoming years, increasing to $16.62 billion by 2029 at a compound annual growth rate (CAGR) of 5.5%. The projected increase during the forecast period is credited to advancements in regenerative medicine, the use of biologic injections, tissue engineering solutions, precision medicine, and surgery aided by robotics. Key trends for the forecast period involve therapies based on stem cells, the use of 3D printing in orthopedics, gene therapy for repairs of cartilage, individualized rehabilitation plans, and telemedicine for post-treatment follow-ups.

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What External and Internal Drivers Are Contributing to the Growth of the Cartilage Degeneration Market?

The continued rise in obesity rates is projected to fuel the expansion of the cartilage degeneration market. Obesity, characterized by an unhealthy buildup of body fat, can negatively impact individuals’ health. It can trigger and expedite cartilage degeneration by elevating compressive forces on the cartilage and inflammatory cytokines. Changes brought on by obesity can inflict several damaging alterations to the entire knee joint structure, including undue stress on the joint, joint misalignment, and muscle weakness. To illustrate, the Government Digital Service, a UK-based governmental entity, reported in May 2023 that approximately 63.8% of adults aged 18 and above were overweight or plagued by obesity in 2021-2022, a slight rise from 63.3% the year before. Additionally, the percentage of obese adults rose by 25.2% between 2020 and 2021, with an estimated 25.9% being classified as obese. Thus, the escalating prevalence of obesity is accelerating the expansion of the cartilage degeneration market.

What Segment Types Define the Cartilage Degeneration Market Structure?

The cartilage degeneration market covered in this report is segmented –

1) By Procedure: Joint Replacements, Chondroplasty, Osteochondral Transplants, Microfracture, Meniscus Transplants, Cell-Based Cartilage Resurfacing, Autologous Chondrocyte Implantation, Other Procedures

2) By Application: Knee, Hip, Other Applications

3) By End User: Hospitals And Specialty Clinics, Ambulatory Surgical Centers, Academic And Research Institutes

Subsegments:

1) By Joint Replacements: Knee Replacement (Partial, Total), Hip Replacement (Partial, Total), Shoulder Replacement (Total, Reverse), Other Joints (Ankle, Elbow, Wrist)

2) By Chondroplasty: Radiofrequency Ablation Chondroplasty, Mechanical Chondroplasty, Thermal Chondroplasty, Arthroscopic Chondroplasty

3) By Osteochondral Transplants: Autografts (OATS), Allografts (Fresh Osteochondral Allografts), Synthetic Implants

4) By Microfracture: Traditional Microfracture, Augmented Microfracture (with scaffolds or matrix implants)

5) By Meniscus Transplants: Allograft Meniscus Transplantation (Cryopreserved, Fresh Frozen), Synthetic Meniscus Implants

6) By Cell-Based Cartilage Resurfacing: Autologous Cell-Based Therapy, Allogeneic Cell-Based Therapy, Stem Cell-Based Cartilage Repair

7) By Autologous Chondrocyte Implantation (ACI): First-Generation ACI, Second-Generation ACI, Third-Generation ACI (MACI)

8) By Other Procedures: Arthroscopic Debridement, Osteotomy, Cartilage Repair Using Synthetic Scaffolds, Injection-Based Therapies (Hyaluronic Acid, PRP, Stem Cell Injections)

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Which Geographic Areas Hold the Strongest Growth Potential in the Cartilage Degeneration Market?

North America was the largest region in the cartilage degeneration market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the cartilage degeneration market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

Which Emerging Trends that Are Influencing the Cartilage Degeneration Industry Evolution?

Leading firms in the cartilage degeneration market are pioneering new products such as Agili-C to aid in bone remodeling and cartilage revival. Agili-C is a readily available, cell-free implant designed to mend cartilage and osteochondral flaws in traumatized and osteoarthritic joints. In July 2023, CartiHeal Ltd., a medical equipment company based in Israel, unveiled its initial commercial implantation of Agili-C. The objective of the implant is to promote the natural regeneration of articular cartilage and subchondral bone rather than dependence on cells or growth factors. Composed from natural calcium carbonate, aragonite, obtained from coral exoskeletons, the implant prompts chondrocytes from the nearby cartilage to move into the framework, leaving an extracellular matrix. This certification enhances the value of the implant by asserting to patients and healthcare practitioners that it serves as a secure and efficacious treatment alternative.

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What Is the Definition of the Cartilage Degeneration Market?

Cartilage degeneration refers to the gradual deterioration or breakdown of cartilage tissue, a smooth, flexible connective tissue covering the ends of bones in joints. Cartilage is a cushion that allows for smooth joint movement by reducing bone friction. Cartilage degeneration leads to pain, stiffness, and decreased joint function.

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