What Is The Long-Term Forecast For The Global Cell And Gene Therapy Contract Development And Manufacturing Organization (CDMO) Market Growing At 26.2% CAGR?
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What Is The Predicted Market Size Of The Cell And Gene Therapy Contract Development And Manufacturing Organization (CDMO) Industry By 2029?
In recent years, the market size of the cell and gene therapy contract development and manufacturing organization (cdmo) has expanded significantly. The market worth is expected to rise from $5.41 billion in 2024 to $6.92 billion in 2025, indicating a compound annual growth rate (CAGR) of 27.9%. The notable growth during the historic period is due to several factors, such as advanced technology, encouraging regulatory structures, increased investment, high occurrence of genetic diseases, and a surge in strategic partnerships.
The market size for cell and gene therapy contract development and manufacturing organizations (cdmo) is anticipated to rise significantly in the upcoming years, reaching a value of $17.57 billion by 2029 with a compound annual growth rate (CAGR) of 26.2%. The expansion during this forecast period will be propelled by factors such as broadened therapeutic uses, advancements in regulations, inflated investments, technological breakthroughs, and worldwide cooperation. Key trends to observe in the forecast period encompass the surging demand for personalized therapies, the augmentation in automation and digitalization, the broadening of manufacturing capabilities, the development of innovative delivery systems, and an intensified emphasis on sustainability and reducing ecological impact.
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Which Factors Are Steering Growth In The Cell And Gene Therapy Contract Development And Manufacturing Organization (CDMO) Market?
The surge in cancer incidences is predicted to boost the expansion of the cell and gene therapy contract development and manufacturing organization (CDMO) market. Cancer, known as a collective term for disorders marked by uncontrolled proliferation and dissemination of unusual cells in the body, is primarily due to aging demographics, shifted living behaviors, environmental interaction, and heightened detection techniques. The role of a cell and gene therapy contract development and manufacturing organization (CDMO) is to diminish the prevalence of cancer by creating and producing advanced, patient-specific treatments that improve both effectiveness and patient results. As an example, Macmillan Cancer Support, a UK-based non-profit organization, forecasted in October 2022 that the count of cancer patients in the UK may rise from 3 million in 2022 to 3.5 million in 2025, subsequently to 4 million in 2030, and finally to 5.3 million by 2040. Hence, the escalating incidences of cancer intensify the growth of the cell and gene therapy contract development and manufacturing organization (CDMO) market.
Which Segment Accounts For The Largest Share In The Cell And Gene Therapy Contract Development And Manufacturing Organization (CDMO) Market?
The cell and gene therapy contract development and manufacturing organization (cdmo)market covered in this report is segmented –
1) By Product Type: Gene Therapy; Gene-Modified Cell Therapy; Cell Therapy
2) By Phase: Phase 1; Phase 2; Phase 3; Phase 4
3) By Indication: Oncology; Infectious Diseases; Neurological Disorders; Rare Diseases; Other Indications
Subsegments:
1) By Gene Therapy: Viral Vector-Based Gene Therapy; Non-Viral Gene Therapy; Plasmid DNA-Based Gene Therapy
2) By Gene-Modified Cell Therapy: CAR-T Cell Therapy; TCR-T Cell Therapy; NK Cell Therapy
3) By Cell Therapy: Stem Cell Therapy; Progenitor Cell Therapy; Immune Cell Therapy
Which Disruptive Trends Are Driving Change Across The Cell And Gene Therapy Contract Development And Manufacturing Organization (CDMO) Market?
Leading firms in the cell and gene therapy contract development and manufacturing organization (CDMO) market are concentrating on broadening their offerings with innovative options such as PluriMatrix technology. This technology aims to boost the scalability, efficacy, and quality of cell-based product manufacturing. It is a custom-made system designed for the mass production of cell-based products. This state-of-the-art technology enables the 3D expansion of cells on a large scale, assuring a high yield and consistent quality through an automated, fully regulated, and validated procedure. For example, in January 2024, Pluri, a biotech company from Israel, unveiled PluriCDMO, a fresh business unit that provides cell therapy manufacturing services as a contract development and manufacturing organization (CDMO). This newly formed department encompasses a 47,000-square-foot production facility that complies with good manufacturing practice (GMP) for cell therapy. Pluri’s latest division offers comprehensive services that span from the initial preclinical phases to late-stage clinical experiments and commercialization. It includes process and analytical development, scale-up, validation, logistics, automation, and regulatory-approved comparability studies, as per the company’s declaration. The company utilizes its groundbreaking PluriMatrix technology to provide cutting-edge cell therapy manufacturing services.
Who Are The Dominant Players In The Cell And Gene Therapy Contract Development And Manufacturing Organization (CDMO) Market Today?
Major companies operating in the cell and gene therapy contract development and manufacturing organization (CDMO) market are Pfizer Inc., Merck & Co. Inc., Thermo Fisher Scientific Inc., Novartis AG, FUJIFILM Diosynth Biotechnologies, AGC Biologics, Ajinomoto Co Inc., Lonza Group, Catalent Inc., Charles River Laboratories International Inc., Sartorius Stedim Biotech, Samsung Biologics Co Ltd., WuXi Biologics, Recipharm AB, Almac Group Ltd., KBI Biopharma, Rentschler Biopharma, Bio Elpida, Oxford BioMedica Plc, Avid Bioservices Inc., Cell and Gene Therapy Catapult, VGXI Inc., Genezen Laboratories Inc., Pluri Inc., OmniaBio Inc.
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What Regional Factors Are Accelerating Growth In The Cell And Gene Therapy Contract Development And Manufacturing Organization (CDMO) Market?
North America was the largest region in the cell and gene therapy contract development and manufacturing organization (CDMO) market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the cell and gene therapy contract development and manufacturing organization (CDMO) market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
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