Medical Equipment

NGS-Based RNA-Sequencing Market Forecast: What to Expect by 2029

November 14, 2025 by Marketing Posting

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What Are The Forecasted Market Size Estimates For The NGS-Based RNA-Sequencing Market Between 2025 And 2029?

The market for next-generation sequencing (NGS)-based RNA sequencing has experienced substantial expansion over the past few years, projecting a rise from its 2024 valuation of $3.41 billion to $4.2 billion the following year, reflecting a compounded annual growth rate (CAGR) of 23.3%; this upward trajectory throughout the historical period stems from factors such as expanding genomic research programs, decreases in the expense associated with sequencing procedures, ongoing efforts in pharmaceutical discovery and advancement, the push toward individualized healthcare solutions, and the progressively wider acceptance of NGS technologies.

Exponential expansion is projected for the next several years in the market centered around next-generation sequencing based RNA sequencing, with its valuation set to reach $10.26 billion by 2029, achieving a compound annual growth rate (CAGR) of 25.0%; this upward trajectory in the projected timeframe is fueled by advancements in clinical diagnostics, worldwide collaborative efforts, the establishment of ethical and regulatory structures, ongoing research in agriculture and environmental science, and the field of green genomics.Key developments anticipated throughout this forecast period encompass the rise of single-cell RNA sequencing (scRNA-seq), the emergence of spatial transcriptomics, increasing focus on epitranscriptomics, deeper integration across multi-omics platforms, and developments supporting sustainable agricultural practices.

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Which Drivers Are Impacting The NGS-Based RNA-Sequencing Market?

The expansion of NGS-based RNA sequencing as a market driver is directly attributable to the advancements in precision medicine, which empowers clinicians to formulate customized treatment strategies and make therapeutic choices informed by a patient’s genetic disease profile. This trend is particularly pronounced in addressing complex ailments like cancer through targeted therapies. NGS-based RNA sequencing proves invaluable in pinpointing the fundamental etiology of an illness, facilitating the prescription of highly specific precision medicines for intervention. Illustratively, data from a February 2023 publication by the Personalized Medicine Coalition (PMC), an American non-profit entity, showed that personalized medicines constituted 35% of novel NMEs authorized in 2021, and this momentum persisted with 12 new endorsements in 2022, sustaining a consistent representation of no less than 25% of all new drug approvals across the last eight years, a substantial leap from their sub-10% level seen ten years prior. Consequently, the rising necessity for precision medical interventions directly correlates with an anticipated surge in the need for NGS-based RNA sequencing capabilities.

How Is The NGS-Based RNA-Sequencing Market Classified Into Different Segments?

The ngs-based rna-sequencingmarket covered in this report is segmented –

1) By Product And Service: Sample Preparation Products, Sequencing Platforms and Consumables, Sequencing Services, Data Analysis, Storage, and Management

2) By Technology: Sequencing by Synthesis, Ion Semiconductor Sequencing, Single-molecule Real-time Sequencing, Nanopore Sequencing

3) By Application: Expression Profiling Analysis, Small RNA Sequencing, De Novo Transcriptome Assembly, Variant Calling and Transcriptome Epigenetics

4) By End User: Research & Academia, Hospitals & Clinics, Pharmaceutical & Biotechnology Companies, Other End Users

Subsegments:

1) By Sample Preparation Products: RNA Extraction Kits, Library Preparation Kits, Reverse Transcription Kits, Quality Control Reagents

2) By Sequencing Platforms And Consumables: Sequencing Instruments, Sequencing Consumables

3) By Sequencing Services: Contract Sequencing Services, Custom Library Preparation Services, Consultation And Experimental Design Services

4) By Data Analysis, Storage, And Management: Bioinformatics Software, Data Analysis Services, Cloud-Based Data Storage Solutions, Data Management Platforms

What Are The Major Trends Driving The Growth Of The NGS-Based RNA-Sequencing Market?

In the realm of NGS-based RNA sequencing, strategic alliances represent a pivotal development, as organizations collaborate with firms specializing in this area to penetrate untapped markets and capitalize on shared assets. Illustrating this trend, in May 2022, the U.S. Department of Health and Human Services’ Biomedical Advanced Research and Development Authority (BARDA) established collaborations with various academic and industry entities, intending to enhance the ability to react rapidly to public health crises and to engineer a new diagnostic tool capable of identifying all known and newly appearing respiratory RNA viruses within one comprehensive test.

Who Are The Core Companies Influencing The NGS-Based RNA-Sequencing Market Landscape?

Major companies operating in the ngs-based rna-sequencing market include Illumina Inc., Thermo Fisher Scientific Inc., Oxford Nanopore Technologies Ltd., Agilent Technologies Inc., BGI Group, QIAGEN N.V., PerkinElmer Inc., Eurofins Scientific SE, Bio-Rad Laboratories Inc., F. Hoffmann-La Roche Ltd., Hamilton Company, Takara Bio Inc., Tecan Trading AG, GENEWIZ Inc., Novogene Corporation, Macrogen Inc., Zymo Research Corp., Lexogen GmbH, Partek Incorporated, GATC Biotech AG, Becton, Dickinson and Company, Genohub LLC, BaseClear B.V., Genewave SAS, Otogenetics Corporation, SeqLL LLC, GenXPro GmbH, Genotypic Technology Pvt. Ltd.

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What Are The Key Regional Factors Influencing The NGS-Based RNA-Sequencing Market Growth?

North America was the largest region in the NGS-based RNA sequencing market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the ngs-based rna-sequencing market report include Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

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