Uncover key drivers, emerging technologies, and competitive movements shaping the automated next-generation sequencing (ngs) library preparation market from 2025–2034 with trusted insights from The Business Research Company
What Are The Future Growth Projections For The Automated Next-Generation Sequencing (NGS) Library Preparation Market Size?
The automated next-generation sequencing (NGS) library preparation market size has seen substantial growth in recent times. Its valuation is projected to increase from $0.63 billion in 2024 to $0.72 billion in 2025, reflecting a compound annual growth rate (CAGR) of 13.8%. This historical expansion can be attributed to several factors, including the increasing application in infectious disease surveillance, a rise in funding for genomic research, expanded implementation during pandemics, improved accessibility for research laboratories, and its growing use in precision medicine.
The automated next-generation sequencing (NGS) library preparation market is anticipated to undergo rapid expansion in the upcoming years. It is projected to grow to $1.20 billion in 2029, achieving a compound annual growth rate (CAGR) of 13.4%. This expansion during the forecast period can be attributed to factors such as increasing adoption in clinical diagnostics, rising demand for personalized medicine, growing applications in oncology research, an increasing need for high-throughput sequencing, and a rising focus on reducing turnaround time. Key trends identified for the forecast period include advancements in workflow efficiency, the integration of artificial intelligence in data analysis, technology-driven standardization of protocols, developments in user-friendly systems, and advancements in cloud-based data solutions.
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Which Factors Are Steering Growth In The Automated Next-Generation Sequencing (NGS) Library Preparation Market?
The expanding scope of gene therapy is anticipated to fuel the advancement of the automated next-generation sequencing (NGS) library preparation market moving forward. Gene therapy involves modifying an individual’s genes to treat or prevent diseases. The growth in gene therapy is attributed to the increasing prevalence of genetic disorders that necessitate precise and enduring therapeutic interventions. Automated NGS library preparation is employed in gene therapy for accurate analysis and validation of genetic alterations, achieved by preparing high-quality DNA or RNA samples for sequencing. For instance, in April 2024, according to the American Society of Gene and Cell Therapy, a US-based non-profit medical and scientific organization, the number of phase III gene therapy clinical trials in the fourth quarter surged by 10%, marking the first quarterly increase since the third quarter of 2022. Consequently, the uptick in gene therapy is propelling the growth of the automated next-generation sequencing (NGS) library preparation market.
How Is The Automated Next-Generation Sequencing (NGS) Library Preparation Market Organized By Different Segments?
The automated next-generation sequencing (NGS) library preparation market covered in this report is segmented
1) By Type: Targeted Genome Sequencing, Whole Genome Sequencing, Whole Exome Sequencing, Other Sequencing Types
2) By Workflow: Nucleic Acid Extraction, Fragmentation, Adapter Ligation, Purification And Quantification
3) By Application: Drug And Biomarker Discovery, Disease Diagnostics, Other Applications
4) By End-Use: Hospitals And Clinics, Academic And Research Institutions, Pharmaceutical And Biotechnology Companies, Other End-Users
Subsegments:
1) By Targeted Genome Sequencing: Amplicon-Based Targeted Sequencing, Hybridization Capture-Based Targeted Sequencing, Custom Targeted Panels, Pre-designed Gene Panels
2) By Whole Genome Sequencing: Human Whole Genome Sequencing, Animal Whole Genome Sequencing, Plant Whole Genome Sequencing, Microbial Whole Genome Sequencing
3) By Whole Exome Sequencing: Standard Exome Sequencing, Clinical Exome Sequencing, Custom Exome Panels, Ultra-Rapid Exome Sequencing
4) By Other Sequencing Types: RNA Sequencing (RNA-Seq), Epigenome Sequencing, Metagenomic Sequencing, Single-Cell Sequencing
What Current And Upcoming Trends Are Shaping The Automated Next-Generation Sequencing (NGS) Library Preparation Market?
Major companies operating in the automated next-generation sequencing (NGS) library preparation market are concentrating on developing advanced technologies, such as Xpandomer technology, to boost sequencing speed, elevate data accuracy, and increase scalability, thus optimizing workflows and facilitating more efficient and reliable genomic analysis. Xpandomer technology functions as an advanced deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) sequencing method, converting a target nucleic acid molecule into a synthetic, expanded polymer known as an Xpandomer, which is approximately 50 times longer than the original deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) strand. For example, in February 2025, Roche AG, a Switzerland-based biotechnology company, introduced Sequencing by Expansion, a leading-edge sequencing platform crafted to improve genomic resolution for advanced diagnostics, disease research, and precision medicine applications. This inventive automated next-generation sequencing (NGS) library preparation system simplifies intricate workflows, improves data quality, and speeds up genomic analysis to support advanced research and personalized medicine. The Sequencing by Expansion platform demonstrates high adaptability, allowing for accurate analysis of diverse genomic alterations across a broad spectrum of diseases, including cancer and rare genetic disorders, by improving resolution and accuracy to provide deeper biological insights.
Who Are The Most Influential Companies In The Automated Next-Generation Sequencing (NGS) Library Preparation Market?
Major companies operating in the automated next-generation sequencing (NGS) library preparation market are F. Hoffmann-La Roche Ltd., Thermo Fisher Scientific Inc., Agilent Technologies India Private Limited, Illumina Inc., Beckman Coulter Inc., Bio-Rad Laboratories Inc., IDT Corporation, Tecan Group AG, Hamilton Company, Takara Bio Inc., 10x Genomics Inc., Oxford Nanopore Technologies plc, Twist Bioscience Corporation, New England Biolabs Inc., SPT Labtech Limited, Watchmaker Genomics Inc., Pillar Biosciences Inc., Aurora Biomed Inc., BGI Group, SEQWELL INC., and Hudson Robotics Inc.
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Which Region Dominates The Automated Next-Generation Sequencing (NGS) Library Preparation Market Today?
North America was the largest region in the automated next-generation sequencing (NGS) library preparation market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the automated next-generation sequencing (NGS) library preparation market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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