Global Upstream Bioprocessing Market
Healthcare Services

Upstream Bioprocessing Forecast Report – Designed for Decision Makers and Product Teams

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#What Is the Estimated Market Size of the Upstream Bioprocessing Market In 2029?#_x000D_

The market size of upstream bioprocessing has seen a swift expansion in the past few years. It is anticipated to skyrocket from $12.03 billion in 2024 to a striking $13.66 billion in 2025, boasting a compound annual growth rate (CAGR) of 13.6%. The notable growth during the historic period is due to the escalated need for the optimization of processes and the production of biomolecules that are efficient, safe, and devoid of contamination. It is also due to the commercial triumph and the soaring demand for bio-therapeutics, the rising prevalence of chronic diseases, the increased application of process analytical technology, and the amplified research towards developing biosimilars._x000D_

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#What Growth Rate Is Forecasted for the Upstream Bioprocessing Market by 2029?#_x000D_

The market size of upstream bioprocessing is predicted to experience a swift expansion in the subsequent few years. Its valuation will escalate to $22.43 billion by the year 2029, witnessing a compound annual growth rate (CAGR) of 13.2%. The growth speculated for the forecast period could be due to several factors such as adoption of single-use bioreactors for commercial purposes, delegation of biopharmaceutical manufacturing tasks, booming growth of the pharmaceutical and biotechnology sectors, increased acceptance of single-use upstream bioprocessing, and a rise in collaborations, acquisitions, mergers, and partnerships. The forecast period is also expected to see key trends like enhancement in R&D investment in the biopharmaceutical sector, progress in technologies, evolution in upstream bioprocessing technologies, and the introduction of advanced filtration technologies and new technologies._x000D_

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#Which Key Companies Are Shaping the Future of the Upstream Bioprocessing Market?#_x000D_

Major companies operating in the upstream bioprocessing market are Thermo Fisher Scientific Inc., Danaher Corp, Merck KGaA, GE HealthCare Technologies, Parker Hannifin Corp, Corning Inc., AGC Biologics, Avantor, AGC Inc., Boehringer Ingelheim International GmbH, Catalent Inc., Sartorius AG, Entegris Inc., Getinge AB, Bio-Rad Laboratories Inc., Samsung Biologics Co. Ltd., Eppendorf AG, Repligen Corporation, Takara Bio Inc., KBI Biopharma Inc., Rentschler Biopharma SE, Just Biotherapeutics Inc., PBS Biotech Inc., Stobbe Group, Applikon Biotechnology_x000D_

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#Which Factors Are Driving Demand in the Upstream Bioprocessing Industry?#_x000D_

The upstream bioprocessing market’s expansion is expected to be driven by the increasing trend of outsourcing biopharmaceutical manufacturing. This process involves entrusting some production stages to external bodies such as contract manufacturing organizations (CMOs) or contact development and manufacturing organizations (CDMOs). Key motivators behind this outsourcing trend include cost efficiency, focus on core competencies, production scalability, access to specialized expertise, and risk management. Consequently, it speeds up product development within the upstream bioprocessing market by tapping into external expertise, simplifying operations, and reducing cost. As predicted by BDO USA, a member firm of BDO International in the US, by 2025, 44% of the projected 7,500kL global mammalian capacity will be under the control of CDMOs and hybrid manufacturing companies. Hence, the trend of outsourcing biopharmaceutical manufacturing is significantly bolstering the growth of the upstream bioprocessing industry._x000D_

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#How Is the Upstream Bioprocessing Market Segmented by Several Divisions?#_x000D_

The upstream bioprocessing market covered in this report is segmented –_x000D_

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1) By Product type: Bioreactors, Fermenters, Cell Culture Media, Filters, Bags And Containers_x000D_

2) By Workflow: Media Preparation, Cell Culture, Cell Separation_x000D_

3) By Usage type: Single-Use, Multi-Use_x000D_

4) By Mode: In House, Outsourced_x000D_

5) By End User: Contract Development and Manufacturing Organization (CDMOs) Or Contract Research Organization (CROs), Research And Academic Institutes, Biopharmaceutical Companies_x000D_

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Subsegments:_x000D_

1) By Bioreactors: Single-Use Bioreactors, Multi-Use Bioreactors_x000D_

2) By Fermenters: Laboratory Fermenters, Pilot Scale Fermenters, Industrial Fermenters_x000D_

3) By Cell Culture Media: Powdered Media, Liquid Media_x000D_

4) By Filters: Sterile Filters, Air Filters, Capsule Filters_x000D_

5) By Bags And Containers: Single-Use Bags, Bioprocess Containers, Storage Bags_x000D_

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#What are the Emerging Market Trends Driving the Growth of the Upstream Bioprocessing Industry?#_x000D_

In the upstream bioprocessing market, many leading companies are making efforts to create superior bioreactors designed to satisfy the requirements of cell culture processes, thus improving efficiency, adaptability, and scalability. Bioreactors are critical elements in upstream bioprocessing, facilitating the proficient and managed manufacture of biopharmaceuticals through cell cultivation and biomolecule synthesis. For example, Cytiva, a company from the USA that offers life science products and solutions, unveiled X-platform bioreactors in April 2023. These products are crafted to simplify single-use upstream bioprocessing methods. The bioreactors are composed of a tank, a cabinet assembly, and a human-machine interface (HMI), which is a modular layout that allows adaptable configurations without the need for customized hardware or single-use bags. The design features that enhance usability consist of an optimal vessel featuring a fully opening door, baffles, and advanced cable management. Moreover, the Bioreactor Scaler tool online assists in determining the ideal parameters for successful scale-up._x000D_

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#Which Regions Are Driving Growth in the Upstream Bioprocessing Market?#_x000D_

North America was the largest region in the upstream bioprocessing market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the upstream bioprocessing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa._x000D_

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#This Report Delivers Insight On: #_x000D_

1. How big is the upstream bioprocessing market, and how is it changing globally?_x000D_

2. Who are the major companies in the upstream bioprocessing market, and how are they performing?_x000D_

3. What are the key opportunities and risks in the upstream bioprocessing market right now?_x000D_

4. Which products or customer segments are growing the most in the upstream bioprocessing market?_x000D_

5. What factors are helping or slowing down the growth of the upstream bioprocessing market?_x000D_

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