The Business Research Company’s global market reports are now updated with the latest market sizing information for the year 2024 and forecasted to 2033

The ribose-nucleic acid (RNA)-based therapeutics market has experienced significant growth in recent years. This blog provides insights into the market’s size, key trends, growth drivers, and major players, with a focus on the future potential of RNA-based therapeutics.

Market Growth Overview

• Strong Growth: The market size of RNA-based therapeutics increased from $14.54 billion in 2023 to $15.79 billion in 2024 at a CAGR of 8.6%.
• Future Projections: The market is expected to reach $22.30 billion by 2028, growing at a CAGR of 9.0%.
• Historic Growth Factors: Increased investments, discovery of RNA interference (RNAi), clinical successes of antisense oligonucleotides (ASOs), and regulatory support fueled the market’s growth.

Key Drivers of Market Expansion

• Rising Cancer Prevalence: The increasing global prevalence of cancer is a major driver. Cancer cases are expected to rise from 151,000 in 2021 to 185,000 by 2030 in Australia alone, according to the Australian Institute of Health and Welfare.
• RNA Therapeutics in Cancer Treatment: RNA-based therapies target the genetic mechanisms of cancer, offering promising treatment options that can address the growing number of cases.
• Regulatory Support: Governments and regulatory bodies have offered frameworks and guidelines to fast-track RNA-based therapeutic development.

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Emerging Trends in RNA-Based Therapeutics

• Advanced Delivery Systems: Innovations in delivery technologies are enhancing the efficacy of RNA-based drugs.
• Multi-Target RNA Therapeutics: RNA therapies are evolving to target multiple disease mechanisms, broadening their applicability.
• Customized RNA Therapies: Personalized RNA treatments are emerging as a major trend, allowing for tailored treatment approaches.
• AI and Machine Learning Integration: AI is being used to optimize drug discovery and design, accelerating the development of RNA-based therapies.
• Regulatory Advancements: Ongoing improvements in regulatory pathways are facilitating faster approvals and commercialization of RNA-based drugs.

Key Market Segments

• By Type: RNA Interference (RNAi), RNA Antisense
• By Technology: Enabling Technology, Enabled Technology
• By Therapeutic Area: Oncology, Genetic Disorders, Ophthalmology, Hematological Disorders, Acute Hepatic Porphyria (AHP), Other Therapeutic Areas
• By End User: Research Institutes, Hospitals, and Clinics

The Role of mRNA-Based Vaccines

• mRNA Booster Vaccines: Major companies are focused on developing mRNA-based vaccines to address new viral variants. These vaccines use messenger RNA to enhance the body’s immune response.
• Example of Innovation: In June 2023, Gennova Biopharmaceuticals launched GEMCOVAC-OM, India’s first mRNA booster vaccine targeting the Omicron variant of COVID-19. This vaccine is designed to enhance immunity against emerging viral variants, showcasing the potential of mRNA technology.

Leading Players in the Market
Key players in the RNA-based therapeutics market include:

• Pharmaceutical Companies: F. Hoffmann-La Roche AG, Eli Lilly and Company, Novo Nordisk A/S, Regeneron Pharmaceuticals, Biogen Inc., Alnylam Pharmaceuticals, Sarepta Therapeutics, and BioNTech.
• Biotech Firms: Akcea Therapeutics Inc., Dicerna Pharmaceuticals, Quark Pharmaceuticals, Tekmira Pharmaceuticals, ReCode Therapeutics, and Benitec Biopharma Inc.
• Research Institutions: University of Oxford, Houston Methodist Hospital

Regional Insights

• North America Dominates: North America was the largest region in the RNA-based therapeutics market in 2023.
• Global Expansion: The regions covered in the RNA-based therapeutics market include Asia-Pacific, Western Europe, Eastern Europe, South America, the Middle East, and Africa, each poised to see market growth.

Conclusion
The RNA-based therapeutics market is on a strong growth trajectory, driven by advancements in technology, regulatory support, and increasing applications, particularly in cancer treatment. With continued innovation in RNA delivery systems and the integration of AI, the market is poised to expand further, offering promising therapeutic solutions for various diseases.

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