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What Growth Opportunities are Expected to Drive the Oligonucleotide Synthesis Market’s CAGR Through 2034?

The oligonucleotide synthesis market has grown rapidly in recent years. It is expected to increase from $10.33 billion in 2024 to $11.94 billion in 2025, at a CAGR of 15.6%. This expansion has been fueled by advancements in biomedical research, therapeutic developments, biotechnology innovations, genomic studies, and the increasing use of DNA technologies.

The oligonucleotide synthesis market is set to expand rapidly, reaching $22.29 billion by 2029 with a CAGR of 16.9%. Growth will be fueled by advancements in diagnostic tools, increasing applications of RNA interference (RNAi) therapies, developments in regenerative medicine, progress in nanotechnology, and innovations in gene editing. Major trends will include targeted drug development, the introduction of novel delivery systems, automation in synthesis processes, advancements in CRISPR-Cas technology, and the expansion of next-generation sequencing (NGS).

What Drivers Are Shaping the Growth of the oligonucleotide synthesis Market?

The increasing prevalence of chronic diseases is expected to drive the growth of the oligonucleotide synthesis market. Oligonucleotides help manage chronic diseases by targeting specific genes or RNA, potentially modulating gene expression to treat these conditions. The World Health Organization reported in September 2022 that 74% of global deaths are due to non-communicable diseases, with cardiovascular diseases and cancer as major contributors. This rise in chronic diseases is promoting the growth of the oligonucleotide synthesis market.

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What Are the Leading Industry Players Dominating the Oligonucleotide Synthesis Market?

Major companies operating in the oligonucleotide synthesis market include:

• Thermo Fisher Scientific Inc._x000D_

• Danaher Corporation_x000D_

• Merck KGaA_x000D_

• GE HealthCare Technologies Inc._x000D_

• Eurofins Scientific SE_x000D_

What Are the Latest Trends Leading to Disruption in the Oligonucleotide Synthesis Market?

Product innovation is also a key trend in the oligonucleotide synthesis market. Companies in this market are developing new products to maintain their competitive position. For example, in July 2024, Ansa Biotechnologies, Inc., a US-based manufacturer of complex DNA, launched Ansa Clonal DNA and Ansa DNA Fragments. Ansa Clonal DNA provides sequence-perfect, clonal DNA up to 600 base pairs, eliminating assembly needs, while Ansa DNA Fragments offers verified linear double-stranded DNA for a variety of research applications, produced with high precision through an enzymatic synthesis process.

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What Major Market Segments Define the Scope and Growth of the Oligonucleotide Synthesis Market?

The oligonucleotide synthesis market covered in this report is segmented –

1) By Type: Custom Oligos, Predesigned Oligos

2) By Product Type: Oligonucleotides, Reagents, Equipment, Services, Purification, Modification

3) By Application: Therapeutic Applications, Research Applications, Diagnostic Applications

Subsegments:

1) By Custom Oligos: Long Oligonucleotides, Short Oligonucleotides, Modified Oligonucleotides

2) By Predesigned Oligos: Gene-Specific Oligos, Probe Oligos, Primers For PCR And RT-PCR

Which Regions Are Significant to the Growth of the Oligonucleotide Synthesis Market?

North America was the largest region in the oligonucleotide synthesis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the oligonucleotide synthesis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

How Can We Define the Oligonucleotide Synthesis Market and Its Key Components?

Oligonucleotide synthesis is the chemical linking of nucleotides, precisely forming the desired sequenced product. This process is helpful in modern laboratory practice as it offers quick and affordable access to oligonucleotides manufactured to order with the necessary sequence.

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