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What CAGR Will the Personalized Cancer Vaccines Market Achieve During 2025–2034, and What Does It Indicate?

The market for personalized cancer vaccines has seen a solid growth trajectory in the past years. The market size is projected to rise from $242.29 billion in 2024 to $259.11 billion in 2025, with a compound annual growth rate (CAGR) of 6.9%. Factors contributing to this growth during the historical period include progress in genomic research, the evolution of targeted therapies, a deeper comprehension of tumor immunology, advancements in vaccine technology, and increasing clinical trial data that supports efficacy.

Strong expansion is anticipated in the personalized cancer vaccines market over the upcoming years, with its size predicted to reach $336.03 billion in 2029, reflecting a compound annual growth rate (CAGR) of 6.7%. This expansion during the forecast period can be due to advances in precision medicine, augmented funding for cancer research, an increasing number of cancer cases, enhancements in genetic sequencing technologies, and a surging interest in personalized treatment options. Significantly, the forecast period is likely to see trends such as the adoption of artificial intelligence for designing vaccines, development in multi-antigen and neoantigen-based vaccines, growing utilization of liquid biopsies for tumor monitoring, extending combination therapies, and emphasizing personalized treatment regimens.

Which Drivers Are Expected to Have the Greatest Impact on the Personalized Cancer Vaccines Market’s Growth?

The rise in cancer occurrences is projected to boost the expansion of the personalized cancer vaccine market. Cancer is characterized by uncontrolled cell growth that can infiltrate other body parts. Factors such as aging populations, alterations in lifestyle, environmental pollutants, genetic susceptibilities, and enhanced diagnostic methods contribute to the rise of cancer. Personalized cancer vaccines counteract this by focusing on distinct tumor antigens individual to each patient, bolstering the immune system’s capacity to identify and eliminate cancer cells. For example, data from the Australian Institute of Health and Welfare revealed that in Australia, the diagnosed cancer cases saw an increase from 160,570 in 2022 to 164,694 in 2023, marking a significant surge within a year. Consequently, the rising instances of cancer are fueling the expansion of the personalized cancer vaccine market.

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Who Are the Key Firms Paving the Way for Growth in the Personalized Cancer Vaccines Market?

Major companies operating in the personalized cancer vaccines market are Merck & Co Inc., GlaxoSmithKline Plc, NEC Corporation, Moderna Inc., Catalent Inc., UCLA Health, Genetech Inc., NHS England, CureVac AG, Personalis Inc., Achilles Therapeutics Plc, Healio, Moffitt Corporation, BioPharma APAC, Celebrity Angels, EpiVax Therapeutics Inc., Evaxion Biotech AS, Geneos Therapeutics Inc., IFL Sciense, ISA Pharmaceuticals BV, Oxford Global, Kintara Therapeutics, VAXIMM Gmbh

What Are the Most Influential Trends Currently Shaping the Personalized Cancer Vaccines Market?

Significant companies in the personalized cancer vaccine market are concentrating on the evolution of advanced therapeutic strategies, such as personalized immunotherapy, for precision in treating specific cancer mutations. These novel solutions are tailored treatments designed according to a patient’s unique genetic and tumor profile to augment the immune system’s reactions to cancer. For example, in August 2024, UCLA Health, a healthcare organization based in the United States, initiated a groundbreaking clinical trial to assess the safety and efficiency of a new cancer vaccine. This vaccine, developed at UCLA, employs a personalized immunotherapy method that targets the H3 G34 mutation discovered in diffuse hemispheric gliomas, a notably aggressive brain tumor commonly diagnosed in adolescents and young adults. The method uniquely engages dendritic cells to trigger the immune system against the specific RNA disruptions generated by this mutation. This innovative approach, which has demonstrated potential in treating other cancers, intends to enhance prognosis for patients typically subjected to restricted treatment alternatives and brief survival periods.

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Which Key Segments Stand Out in Understanding the Composition of the Personalized Cancer Vaccines Market?

The personalized cancer vaccinesmarket covered in this report is segmented –

1) By Treatment Type: Preventive Cancer Vaccines, Therapeutic Cancer Vaccines

2) By Cancer Type: Lung Cancer, Breast Cancer, Colorectal Cancer, Leukemia, Prostate Cancer, Cervical Cancer, Glioblastoma

3) By Mechanism Of Action: Tumor Associated Antigens (TAAs), Tumor Specific Antigens (TSAs), Somatic Mutations In Cancer Pharmacogenomics, Pharmacogenomics Towards Genomic Polymorphism, Other Mechanisms Of Action

4) By Route Of Administration: Injectables, Other Routes Of Administration

5) By End Use: Hospitals, Clinic, Other End Users

Subsegments:

1) By Preventive Cancer Vaccines: HPV Vaccines, Hepatitis B Vaccines, Combination Vaccines

2) By Therapeutic Cancer Vaccines: Dendritic Cell Vaccines, Peptide-Based Vaccines, DNA Vaccines, RNA Vaccines, Whole Cell Vaccines

Which Regions Are Essential for the Growth of the Personalized Cancer Vaccines Market?

North America was the largest region in the personalized cancer vaccines market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the personalized cancer vaccines market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

What Key Elements Shape the Definition of the Personalized Cancer Vaccines Market?

Personalized cancer vaccines refer to treatments tailored to an individual’s unique tumor profile, aiming to stimulate their immune system to target and destroy cancer cells. They improve the body’s ability to recognize and fight specific cancer types, potentially enhancing treatment efficacy and reducing recurrence.

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