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What is the Forecasted Expansion Rate of the Protein Expression Market Over the 2025–2034 Period?

Recently, the size of the protein expression market has seen significant growth. It is projected to increase from $3.58 billion in 2024 to $3.98 billion in 2025, demonstrating a compound annual growth rate (CAGR) of 11.1%. The expansion in the historic period is credited to factors such as scientific research, advancements in biotechnology, biopharmaceutical development, strides in drug discovery and growth in the healthcare industry.

Projected advancements in the protein expression sector suggest that the market’s value may experience swift expansion in the coming years. Targeted at $6.57 billion by 2029, the industry is forecasted to grow at a compound annual growth rate (CAGR) of 13.4%. This surge during the forecasted period can be credited to the rise of personalized medicine, the biosimilars market, drug repurposing, regulatory support, and precision agriculture. The clear trends during this period are expected to be cell-free expression systems, the use of crispr-cas9 for gene editing, sustainable bioprocessing, contract research and manufacturing, and multi-modal expression platforms.

What Are the Primary Drivers Supporting the Growth of the Protein Expression Market?

The protein expression market is experiencing significant growth due to the rising demand for biologics needed to combat various genetic disorders and chronic illnesses. Biologics, medicines originating from or comprising components of living organisms from proteins, tissues, and genes, to allergens, cells, blood components, blood, and vaccines, are being increasingly opted for the treatment of chronic diseases such as cancer, cardiovascular diseases, and genetic disorders. This, in turn, escalates the requirement for protein expression appliances and equipment. The World Health Organization, a specialized agency of the United Nations based in Switzerland, reported in September 2022 that non-communicable diseases or chronic illnesses account for 74% of the annual global deaths, approximated 41 million. Therefore, the increase in reliance on biologics directly propels the protein expression market’s growth.

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Who Are the Leading Organizations Fueling the Expansion of the Protein Expression Market?

Major companies operating in the protein expression market include Agilent Technologies Inc., Bio-Rad Laboratories Inc., Thermo Fisher Scientific Inc., New England Biolabs Inc., Promega Corporation, Qiagen NV, Takara Bio Inc., Merck KGaA, Genscript Biotech Corporation, Life Technologies Corporation, Sigma-Aldrich Corporation, Lucigen Corporation, Synthetic Genomics Inc., Becton, Dickinson & Company, Lonza Group Ltd., Geneva Biotech LLC, Viva Biotech Holdings, Sengenics LLC, ARTES Biotechnology GmbH, Addgene Inc., Profacgen, ProteoGenix Inc., Peak Proteins Ltd., Domainex Ltd., Jena Bioscience GmbH, EMD Millipore Corporation, Oxford Expression Technologies Ltd., Creative Biolabs Inc., Abnova Taiwan Corp, Accelagen Inc.

What Are the Most Influential Trends Currently Shaping the Protein Expression Market?

Top-tier firms in the protein expression market are turning their focus towards launching next-generation solutions like the Visium CytAssist Gene and Protein Expression Assay, aiming to boost revenue growth. The term next-generation solutions capsule superior technologies and methods designed to enhance the performance, precision, and pace of protein expression. In May 2023, for instance, the US biotech company, 10x Genomics Inc., introduced the Visium CytAssist Gene and Protein Expression Assay. This product allows researchers to examine relative protein expression patterns within the human immune system. Using Visium’s distinctive morphology-first technique, the H&E (Hematoxylin and Eosin) staining process can take place before applying any chemical treatments to the tissue sample. This allows for a three-dimensional spatial analysis on the same specimen, while also providing researchers the opportunity to investigate tissue morphology on the same slice used for more in-depth spatial multiomic investigation. The Visium CytAssist Gene and Protein Expression Assay, with its sequencing-based readout, facilitates the concomitant gathering of protein and complete transcriptome gene expression along with histological analysis in a single experiment from one tissue section.

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Which Segments of the Protein Expression Market Hold the Most Potential for Future Development?

The protein expression market covered in this report is segmented –

1) By Protein Expression: Yeast Expression, Mammalian Expression, Algae Expression, Insect Expression, Bacterial Expression, Cell-free Expression

2) By Product: Reagents, Competent Cells, Expression vectors, Services, Instruments

3) By Application: Therapeutic, Industrial, Research

4) By End Use: Pharmaceutical And Biotechnological Companies, Academic Research, Contract Research Organizations

Subsegments:

1) By Yeast Expression: Saccharomyces Cerevisiae, Pichia Pastoris, Kluyveromyces Lactis

2) By Mammalian Expression: Chinese Hamster Ovary (CHO) Cells, Human Embryonic Kidney (HEK) Cells, Vero Cells

3) By Algae Expression: Green Algae, Blue-green Algae (Cyanobacteria)

4) By Insect Expression: Sf9 Cells, Hi5 Cells

5) By Bacterial Expression: Escherichia Coli (E. coli), Bacillus Subtilis

6) By Cell-free Expression: Wheat germ Extract, Rabbit Reticulocyte Lysate

Which Regions Are Most Influential in Expanding the Protein Expression Market?

North America was the largest region in the protein expression market in 2023. Western Europe was the second largest region in the protein expression market. The regions covered in the protein expression market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

What Does the Definition of the Protein Expression Market Include?

Protein expression is a process in which proteins are synthesized, modified, regulated, and controlled in living organisms according to the host cell. Protein expression in the context of protein research can now also refer to the application of lab procedures necessary for protein production.

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