How Will the Downstream Processing Market Grow? Key Trends and Opportunities for 2025 and Beyond
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What fueled the previous growth in the downstream processing market?
The market size of downstream processing has seen a substantial surge in recent times. It is projected to elevate from $31.26 billion in 2024 to a whopping $35.54 billion in 2025, with a compound annual growth rate (CAGR) of 13.7%. Factors leading to this momentous growth during the historical period include an upsurge in biopharmaceutical investments, rigid regulatory standards, worldwide expansion of biopharmaceutical production, and an escalating prevalence of persistent diseases.
What will be the downstream processing market size in the future?
The market size of downstream processing is projected to surge significantly in the coming years, reaching “$58.96 billion by 2029 with a compound annual growth rate (CAGR) of 13.5%. The anticipated growth during the forecast period can be credited to the escalating demand for biopharmaceuticals, emphasis on environmentally-friendly and green processing, synergistic collaborations and partnerships, and increasing adoption of continuous bioprocessing. The increasing demand for personalized medicines also adds to this growth. Key trends expected during this forecast period include the integration of digitalization and industry 4.0, advancements in technology, the adoption of single-use systems, growth in the biopharmaceutical industry, and continuous processing techniques.
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What main drivers are fueling expansion in the downstream processing market?
The growth of the downstream processing market is anticipated to be driven by the rise in healthcare expenditure. Essentially, healthcare expenditure encompasses all costs involved in providing health services, including family planning, nutritional activities, and health-targeted emergency aid. Increased spending in this area stimulates the sales of downstream processing, which is crucial in extracting and purifying drug substances from sources like bacterial or animal cells. For example, the 2021–2030 National Health Expenditure (NHE) report issued by the Centers for Medicare & Medicaid Services, a branch of the US Department of Health and Human Services, projected in March 2022 that national health spending would grow by an annual average of 5.1% from 2021 to 2030, amounting to about $6.8 trillion by 2030. Moreover, the report predicts Medicare expenditures to rise at a 7.2% annual rate and Medicaid spending to expand at a 5.6% annual rate between 2021 and 2030. As a result, the escalation in healthcare expenditure is contributing to the expansion of the downstream processing market.
What key areas define the segmentation of the global downstream processing market?
The downstream processing market covered in this report is segmented –
1) By Product: Centrifuges, Dryers, Chromatography Systems, Filters, Evaporators, Other Products
2) By Technique: Purification Techniques, Solid-Liquid Separation, Clarification Or Concentration
3) By Application: Monoclonal Antibody Production, Vaccine Production, Insulin Production, Immunoglobulin Production, Erythropoietin Production, Other Applications
Subsegments:
1) By Centrifuges: Analytical Centrifuges, Preparative Centrifuges
2) By Dryers: Spray Dryers, Freeze Dryers, Fluidized Bed Dryers
3) By Chromatography Systems: Liquid Chromatography Systems, Gas Chromatography Systems, Affinity Chromatography Systems
4) By Filters: Membrane Filters, Depth Filters, Cartridge Filters
5) By Evaporators: Thin Film Evaporators, Forced Circulation Evaporators, Falling Film Evaporators
6) By Other Products: Mixers, Precipitation Systems, Storage Tanks
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Who are the dominant players expanding their reach in the downstream processing market?
Major companies operating in the downstream processing market include Sartorius AG, General Electric Company, Merck KGaA, Thermo Fisher Scientific Inc., Danaher Corporation, Repligen Corporation, Lonza Group Ltd., Eppendorf AG, Corning Corporation, Ashai Kasei Corporation, Finesse Solutions Inc., MilliporeSigma, Pall Corporation, Bio-Rad Laboratories, Charles River Laboratories International Inc., Waters Corporation, Becton Dickinson and Company (BD), Entegris Inc., Novasep, Avantor Sciences, Tecan Group, Agilent Technologies, Boehringer Ingelheim International GmbH, Ahlstrom-Munksjö Oyj, Grifols S.A., GenScript Biotech Corporation
How are evolving market trends shaping downstream processing Strategies?
The trend of product innovations is gaining traction in the downstream processing market. Many of the significant players in this market are concentrating on the development of new technological solutions to solidify their market standing. For instance, in September 2022, Tosoh Bioscience LLC, a US-based firm that operates globally in the chemical and specialty materials sectors, introduced the Octave BIO Multi-Column Chromatography (MCC) system. This system is a comprehensive multi-column chromatography solution for intensifying downstream processes. The system, uniquely designed for enhancing biomolecule purification processes, delivers advanced multi-column chromatography for process development and proof of concept. Its modular design enables it to cater to extensive needs and offers the benefits of MCC’s resin and buffer cost cuts, among other tangible benefits.
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Which regions are emerging as leaders in the downstream processing market?
North America was the largest region in the downstream processing market in 2024.Asia-Pacific is expected to be the fastest-growing region in the global downstream processing market report during the forecast period. The regions covered in the downstream processing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa
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