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How has the oligonucleotide therapy market grown over the years?

The market size of oligonucleotide therapy has experienced a significant surge of late. The market is projected to increase from a value of $5.55 billion in 2024 to $6.18 billion in 2025, representing a compound annual growth rate (CAGR) of 11.4%. Factors contributing to this growth during the historic period include increased research and development investments, the launch of pioneer therapies, the advent of gene-editing methods, early therapeutic breakthroughs, and the introduction of RNAi and antisense oligonucleotide.

What Is the forecasted market size and growth rate for the oligonucleotide therapy market?

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What are the major factors driving growth in the oligonucleotide therapy market?

Global cancer cases are on the rise, a trend that’s expected to fuel the growth of the oligonucleotide therapy market in the prediction period. As of January 2022, the American Cancer Society reports an anticipated 1.9 million new cancer diagnoses, along with 609,360 cancer-related deaths in the United States, averaging 1,670 deaths daily. The most prevalent types of cancer globally – lung, prostate, bowel, and female breast cancer – make up 43% of all new cancer instances. As a result, the escalating incidence rates of cancer worldwide are likely to spur the demand for the oligonucleotide therapy market in the upcoming years.

What key areas define the segmentation of the global oligonucleotide therapy Market?

The oligonucleotide therapy market covered in this report is segmented –

1) By Type: Antisense Oligonucleotide, Aptamer, Other Types

2) By Application: Infectious Diseases, Oncology, Neurodegenerative Disorders, Cardiovascular Diseases, Kidney Diseases, Other End-User

3) By End User: Hospitals, Research Institutes

Subsegments:

1) By Antisense Oligonucleotide: RNA-Targeted Antisense Oligonucleotides, DNA-Targeted Antisense Oligonucleotides, Chemically Modified Antisense Oligonucleotides

2) By Aptamer: DNA Aptamers, RNA Aptamers, Small Molecule Aptamers

3) By Other Types: siRNA (Small Interfering RNA), miRNA (Micro RNA), DNAzyme And Ribozymes, Synthetic Oligonucleotides For Gene Editing

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What are the top market players propelling the growth of the oligonucleotide therapy industry?

Major companies operating in the oligonucleotide therapy market include Pfizer Inc., Merck & Co. Inc., GlaxoSmithKline plc, Gilead Sciences Inc., BioNTech SE, Moderna Inc., Biogen Inc., Jazz Pharmaceuticals plc, QIAGEN Company, Alnylam Pharmaceuticals Inc., Sarepta Therapeutics Inc., Ionis Pharmaceuticals Inc., Akcea Therapeutics Inc., Arrowhead Pharmaceuticals Inc., Dicerna Pharmaceuticals Inc., SomaGenics Inc., Wave Life Sciences Ltd., Exicure Inc., Avidity Biosciences Inc., Miragen Therapeutics Inc., ProQR Therapeutics NV, Regulus Therapeutics Inc., Kastle Therapeutics LLC, Santaris Pharma A/S, InteRNA Technologies B.V., Dynacure S.A., Arcturus Therapeutics Holdings Inc., Intellia Therapeutics Inc., Regeneron Pharmaceuticals Inc., Editas Medicine Inc., Evox Therapeutics Ltd., PepGen Ltd.

What are the key trends shaping the future of the oligonucleotide therapy market?

A significant number of major corporations in the oligonucleotide therapy market include Pfizer Inc., Merck & Co. Inc., GlaxoSmithKline plc, and Gilead Sciences Inc. Other players in the market are BioNTech SE, Moderna Inc., Biogen Inc., and Jazz Pharmaceuticals plc. Additionally, QIAGEN Company, Alnylam Pharmaceuticals Inc., Sarepta Therapeutics Inc., Ionis Pharmaceuticals Inc., Akcea Therapeutics Inc., Arrowhead Pharmaceuticals Inc., Dicerna Pharmaceuticals Inc., and SomaGenics Inc. also feature in the market. Other companies are Wave Life Sciences Ltd., Exicure Inc., Avidity Biosciences Inc., Miragen Therapeutics Inc., ProQR Therapeutics NV, Regulus Therapeutics Inc., Kastle Therapeutics LLC, Santaris Pharma A/S, and InteRNA Technologies B.V. Completing the list are Dynacure S.A., Arcturus Therapeutics Holdings Inc., Intellia Therapeutics Inc., Regeneron Pharmaceuticals Inc., Editas Medicine Inc., Evox Therapeutics Ltd., and PepGen Ltd.

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What regions are dominating the oligonucleotide therapy market growth?

North America was the largest region in the oligonucleotide therapy market in 2024. The regions covered in the oligonucleotide therapy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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