The Business Research Company’s global market reports provide comprehensive analysis on the various markets in 27 industries across 60 geographies.

 According to The Business Research Company’s Difficult-to-Express Proteins Global Market Report 2023, the worldwide market for difficult-to-express proteins is projected to increase from $3.65 billion in 2022 to $4.11 billion in 2023, with a 12.7% CAGR. It is anticipated to reach $6.37 billion in 2027, maintaining an 11.6% CAGR.

What was the major driver in the difficult-to-express proteins market?
Increasing recombinant protein demand drives the difficult-to-express protein market. Recombinant proteins originate from modified DNA, used in diverse applications, including medical disease therapeutics. For instance, Amgen Inc.’s 2022 annual report revealed Prolia’s (Denosumab) 12% sales growth to $3,628 million, emphasizing rising recombinant protein demand in propelling the difficult-to-express protein market.

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What was the key trend in the difficult-to-express proteins market?
Innovative technology development is a prominent trend in the difficult-to-express protein market. Leading companies in this sector prioritize innovative technology to maintain their market position. For example, in January 2023, US-based biotechnology firm Evozyne introduced an AI model, the Protein Transformer Variational AutoEncoder, for therapeutic protein design. This method establishes an efficient framework for training and deploying large language models in biology, offering new potential for data-driven engineered protein design with innovative functionality.

Which was the largest region in the difficult-to-express proteins market?
North America was the largest region in the difficult-to-express proteins market in 2022. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in difficult-to-express proteins report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

Who are the difficult-to-express proteins market prominent players?
Major players in the difficult-to-express proteins market are Thermo Fisher Scientific Inc., Merck KGaA, Lonza Group Ltd, Catalent Inc., Sartorius AG, Charles River Laboratories International Inc., Bio-Rad Laboratories Inc., Samsung Biologics Co. Ltd., Bio-Techne Corp., GenScript Biotech Corporation, Ajinomoto Bio-Pharma Services, Novasep Holding SAS, Rentschler Biopharma SE, BioLegend Inc., Codexis Inc., Enzo Biochem Inc., Sino Biological Inc., Horizon Discovery Ltd., Creative Biolabs Inc., OriGene Technologies Inc., Celonic AG, Cube Biotech GmbH, Lucigen Corporation, Batavia Biosciences Inc., Cytovance Biologics Inc., Alloy Therapeutics Inc., Aragen Bioscience Inc., Selexis SA, LifeSensors Inc., and Bionova Scientific Inc.

Key difficult-to-express proteins market segments
The global difficult-to-express proteins market is segmented –
1) By Protein: Proteases, Kinases, Membrane Proteins, Other Proteins
2) By Expression Of Difficult Proteins: Disulfide-bonded Protein Expression, Membrane Protein Expression, Toxic Protein Expression, Target Protein Insolubility
3) By Technology: Cell-free Protein Synthesis, Prokaryotic Expression Systems, Small Ubiquitin-like Modifier (SUMO) Fusion System, Gene Fusion Systems, Other Technologies
4) By Application: Drug Discovery, Protein Purification, Protein Therapeutics, Disease Diagnostics And Monitoring, Other Applications

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The Difficult-to-Express Proteins Global Market Report 2023  provides a comprehensive overview on the difficult-to-express proteins market size, trends and drivers, opportunities, strategies, and companies analysis. Through our reports businesses can effectively analyze data and frame well-informed strategies

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