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What key factors are powering the surge in the actinic keratosis market right now?

The growth of the actinic keratosis market has been consistent in past years. It’s projected to expand from 2024’s $7.95 billion to $8.44 billion in 2025, demonstrating a compound annual growth rate (CAGR) of 6.1%. The historical growth can be accredited to several factors such as greater exposure to UV radiation, an aging demographic, heightened awareness of skin cancer, the rising incidence of actinic keratosis, improvements in healthcare infrastructure, increased disposable incomes, beneficial government policies, and the growing emphasis on preventive skincare.

How fast Is the actinic keratosis market expected to grow, and what’s its future value?

The market for actinic keratosis is predicted to experience a significant surge in its size in the upcoming years, expanding to a worth of $10.58 billion in 2029 with a CAGR of 7.4%. The growth projected for this period can be credited to a variety of factors including the introduction of ground-breaking therapies, progress in AI-supported diagnostic instruments, growing use of combination therapies, an increase in the demand for non-invasive operations, and the broadening use of tele dermatology. Other contributing factors include the widespread use of photodynamic therapy, heightened awareness about cosmetic results, evolution of targeted biological treatments, improved healthcare spending in developing markets and an increased emphasis on early detection and prevention. A variety of trends are expected to shape the forecast period, including AI-based diagnostic instruments, machine learning for lesion analysis, sophisticated photodynamic therapy systems, wearable UV monitoring gadgets, nanotechnology for drug delivery, 3D imaging for individualized treatments, portable phototherapy devices for home use, early detection biosensors, software for automated lesion classification, and hydrogel-based therapeutic systems.

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What are the leading drivers of growth in the actinic keratosis market?

The surge in instances of extreme sunburns is anticipated to fuel the expansion of the actinic keratosis market. Severe sunburns, characterized by intense skin burns due to overexposure to ultraviolet (UV) radiation, evoke redness, pain, swelling and occasionally blistering. Prolonged exposure to UV radiation, inadequate sun protection measures, heightened outdoor activities during peak UV hours, and escalating temperatures due to climate change are few of the key factors sparking sunburns. Actinic keratosis is a consequence of sunburns, where the DNA in skin cells is damaged by UV radiation, triggering mutations that interfere with regular cell functions, culminating in the formation of precancerous lesions, especially with repeated or sustained sun exposure. For example, as per Melanoma Focus, a charity based in the UK, 201 hospital admissions resulted from sunburn in 2022-23, comprising 89 children and 25 infants under a year old. The charity also discovered that 66% of UK adults from 16 to 65 recalled being sunburned as children, with 65% suffering from blistering due to severe sunburn at least once. This figure escalates to 77% for individuals with light, pale, or white skin. Consequently, the escalating instances of severe sunburns are contributing to the growth of the actinic keratosis market.

What are the key segments defining the actinic keratosis market?

The actinic keratosis market covered in this report is segmented –

1) By Treatment Type: Topical Treatment, Surgical Procedure, Photodynamic Therapy, Other Treatment Types

2) By Distribution Channels: Hospital Pharmacies, Drug Stores And Retail Pharmacies, Online Providers

3) By End-User: Hospitals, Dermatology Clinics, Spas And Rejuvenation Centers, Homecare Settings, Other End-Users

Subsegments:

1) By Topical Treatment: 5-Fluorouracil (5-FU), Imiquimod, Diclofenac, Ingenol Mebutate, Retinoids

2) By Surgical Procedure: Cryotherapy, Curettage And Electrodessication, Excision

3) By Photodynamic Therapy: Aminolevulinic Acid (ALA) Plus Light Therapy, Methyl Aminolevulinate (MAL) Plus Light Therapy

4) By Other Treatment Types: Laser Therapy, Chemical Peels, Combination Therapies

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Who are the key players steering the development of the actinic keratosis market?

Major companies operating in the actinic keratosis market are Pfizer Inc., F. Hoffmann-La Roche AG, Merck & Co. Inc., AbbVie Inc., Sanofi S.A., Bristol-Myers Squibb, Novartis AG, GSK plc, Amgen Inc., Bausch Health Companies Inc., Perrigo Company plc, Galderma SA, Incyte Corporation, Leo Pharma Inc., Almirall S.A., Athenex Inc., G&E Herbal Biotechnology Co. Ltd., Aclaris Therapeutics Inc., Biofrontera Inc., Hill Dermaceuticals Inc.

What are the key trends shaping the future of the actinic keratosis market?

Prominent organizations in the actinic keratosis market are concentrating their efforts on the creation of topical solutions to efficiently address and eradicate precancerous growths, decrease the likelihood of reoccurrence and increase patient adherence through reduced treatment timeframes and enhanced safety parameters. These topical solutions are medicinal creams or gels that are directly applied to the impacted skin containing the active element tirbanibulin, which targets defective keratinocytes to address precancerous growths. For example, in June 2024, Almirall SA, a major biopharmaceutical organization in Spain, received the green light from the US Food and Drug Administration (FDA) for supplemental new drug application (sNDA) to broaden the application scope of its medication, Klisyri, to cover an area of 100 cm2. The treatment Klisyri (tirbanibulin) 1% ointment impedes the multiplication of abnormal keratinocytes, effectively shrinking the precancerous lesion’s quantity and size for treating actinic keratosis (AK) on the face or scalp.

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Which regions are most influential in expanding the actinic keratosis market?

North America was the largest region in the actinic keratosis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the actinic keratosis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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