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What Factors Are Driving the Anticipated Growth Rate of the Acute Kidney Injury Market Through 2034?

Over the past few years, the acute kidney injury market has shown robust growth. It has a projected increase from $5.37 billion in 2024 to $5.74 billion in 2025, translating to a compound annual growth rate (CAGR) of 6.9%. This notable growth during the historical timeframe can be linked to various factors, such as the rising number of chronic illnesses, increasingly aged population, escalating cases of hospital-acquired infections, growing consciousness about renal health, and breakthroughs in critical care medication.

In the forthcoming years, the market size for acute kidney injury is projected to undergo substantial growth. The predicted compound annual growth rate (CAGR) is 6.5%, with a forecasted market size of $7.39 billion in 2029. The expansion during this period will be driven by factors such as the rising incidence of sepsis, increased need for tailored treatment, government initiatives surrounding health care, escalating health care spending in developing markets, and an intensified emphasis on personalized medicine and regenerative therapies. Leading trends anticipated for this period are wearable dialysis tools, artificial intelligence integration into treatment enhancement, transportable renal replacement therapy systems, continuous renal replacement therapy (CRRT) developments, remote patient monitoring, and the incorporation of telemedicine.

What Drivers Are Shaping the Growth of the Acute Kidney Injury Market?

The rising incidence of diabetes is projected to drive the expansion of the acute kidney injury market. Diabetes encompasses a variety of metabolic disorders distinguished by elevated blood glucose levels owing to the body’s insufficient insulin production or cells not properly responding to insulin. The growing incidence of diabetes is attributed to factors like escalating obesity rates, poor dietary habits, lack of physical activity, older demographics, and improved awareness and diagnosis. Acute kidney damage triggers metabolic and inflammatory alterations that could impact insulin sensitivity and glucose balance, underscoring a complicated interaction that could affect diabetes progression and treatment. For example, as reported by the UK’s Office for Health Improvement & Disparities in March 2024, between March 2022 and March 2023, the proportion of individuals with type 1 diabetes who underwent all eight recommended care procedures increased by 22%, and for type 2 diabetes, it rose by 21%, while the percentage reaching the desired HbA1c levels climbed to 37.9%, the highest figure ever recorded by the National Diabetes Audit (NDA). Therefore, the advancing prevalence of diabetes is fuelling the growth of the acute kidney injury market.

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Who are the major industry leaders accelerating growth in the Acute Kidney Injury market?

Major companies operating in the acute kidney injury market are Pfizer Inc., F. Hoffmann-La Roche Ltd, Merck & Co. Inc., Sanofi S.A., Bristol-Myers Squibb Company, Novartis AG, Eli Lilly and Company, Gilead Sciences Inc., Amgen Inc., Fresenius Medical Care AG & Co. KGaA, Asahi Kasei Medical Co. Ltd., Teva Pharmaceutical Industries Ltd., Baxter International Inc., B. Braun Melsungen AG, Nipro Corporation, Nikkiso Co. Ltd., Quark Pharmaceuticals Inc., Kringle Pharma Inc., Aptabio Therapeutics Inc., Alexion Pharmaceuticals Inc., Alloksys Life Sciences B.V., AM-Pharma B.V., Arch Biopartners Inc., Guard Therapeutics International AB

Which Current Trends Are Having the Most Impact on the Acute Kidney Injury Market?

The acute kidney injury (AKI) market is witnessing major firms prioritizing the attainment of regulatory approvals to diversify their product offerings and bring innovative treatment alternatives. These regulatory approvals are official permits issued by regulatory authorities like the FDA or EMA, permitting the sale and marketing of a product once it meets specific safety, quality, and efficacy benchmarks. For example, Mission Therapeutics Ltd., a biotechnology firm based in the UK, was given approval by the FDA to begin a Phase II clinical trial for its principal product, MTX652, aimed at acute kidney injury (AKI) in patients at high risk after heart surgery. The trial will test this unique drug, designed to target the vital pathways in kidney damage and repair in December 2023. The objective is to curb inflammation, inhibit further kidney damage, and stimulate recovery. It is the trial’s distinct aspect that it focuses on harnessing novel therapeutic procedures to tackle the intrinsic molecular triggers of AKI, potentially providing superior treatment alternatives to existing solutions. The safety, efficacy, and pharmacokinetics of MTX652 will be assessed in the Phase II trial, providing critical data that may facilitate wider clinical utilization and potential approval.

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What Are the Major Categories and Their Growth Dynamics in the Acute Kidney Injury Market?

The acute kidney injury market covered in this report is segmented –

1) By Injury: Pre-Renal Kidney Injury, Post-Renal Kidney Injury, Intrinsic Kidney Injury

2) By Treatment Type: Dialysis, Drug Therapy, Urinary Implants

3) By End User: Hospitals, Ambulatory Surgical Centers, Other End Users

Subsegments:

1) By Pre-Renal Kidney Injury: Hypovolemia, Heart Failure-Related Injury, Sepsis-Induced Injury, Renal Artery Stenosis, Hepatorenal Syndrome

2) By Post-Renal Kidney Injury: Ureteral Obstruction, Bladder Outlet Obstruction, Prostate Enlargement (Benign Prostatic Hyperplasia), Kidney Stones, Tumors Affecting Urinary Tract

3) By Intrinsic Kidney Injury: Acute Tubular Necrosis (ATN), Acute Interstitial Nephritis (AIN), Glomerulonephritis, Vasculitis, Rhabdomyolysis-Induced Injury

Which Regions Are Key Players in the Growth of the Acute Kidney Injury Market?

North America was the largest region in the acute kidney injury market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the acute kidney injury market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

What Key Elements Shape the Definition of the Acute Kidney Injury Market?

Acute kidney injury (AKI) refers to a sudden decline in kidney function, leading to an accumulation of waste products, electrolytes, and fluids in the body. It can develop rapidly over hours or days and is often caused by conditions like reduced blood flow, direct kidney damage, or obstruction of the urinary tract.

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