Discover trends, market shifts, and competitive outlooks for the adagen global market report 2025 industry through 2025-2034 with The Business Research Company’s reliable data and in-depth research

How Has The Adagen Market Size Shifted, And What Is the Outlook Through 2034?

The market size for adagen has seen a substantial increase over the past few years. The market is projected to rise from $88.58 million in 2024 to $94.94 million in 2025, with a compound annual growth rate (CAGR) of 7.2%. This notable growth during the historical period is due to factors such as enhanced diagnosis of severe combined immunodeficiency (SCID), increased healthcare spending in developed nations, solid regulatory backing for orphan drugs, a heightened government attention on rare illnesses, and the growth of specialty drug initiatives.

Expectations are high for the adagen market size, with forecasts predicting vigorous expansion in the coming years. By 2029, it is projected to reach a worth of $123.58 million, thanks to a compound annual growth rate (CAGR) of 6.8%. This growth during the forecast period is likely due to continuous enhancements in drug delivery systems, the expanding healthcare infrastructure in developing economies, improved accessibility to enzyme replacement therapies, favorable reimbursement policies, and an increase in genetic disorders prevalence. During the forecast period, the prime trends will consist of the development of biosimilar enzyme replacement therapies, concentration on lowering manufacturing expenses, a rise in the digitalization of healthcare supply chains, partnerships between biotech firms and academic establishments, as well as the progress in long-acting formulations.

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Which Primay Drivers Are Accelerating Growth in the Adagen Market?

The rise in precision medicine practice has been forecasted to contribute to the growth of the adagen market. Precision medicine, an evolving health care approach that personalizes preventative measures and treatment plans according to the unique traits of each patient, has become increasingly prevalent due to technological advancements in genomics, increased biomarker accessibility, the incorporation of artificial intelligence in healthcare, and an intensified demand for individualized genetic profile therapies. The adagen market is nurtured by this growth trend, offering tailored enzyme replacement therapy specifically for patients with a severe combined immunodeficiency (SCID) caused by an adenosine deaminase deficiency, embodying personalized treatment for uncommon genetic disorders. To put this in perspective, the Personalized Medicine Coalition (PMC), a US-based nonprofit umbrella organization, reported in February 2024 based on data from the previous year that the FDA approved 16 personalised treatments for rare diseases, a significant rise from just six approvals in 2022. Therefore, the augmented usage of precision medicine is expected to stimulate the adagen market. The expanding diagnoses of uncommon diseases is slated to positively impact the growth of the adagen market. Technological advancements in genetic testing, an uptick in professional healthcare knowledge, better healthcare facilities and an increased international cooperation for rare disease study, have all contributed to the rise in rare diseases diagnoses. The adagen market responds to this growth by delivering targeted enzyme replacement therapy for severe combined immunodeficiency (SCID), thereby raising awareness, supporting early detections and motivating a greater focus on the research of rare genetic disorders and their treatments. Notably, the Genetic Alliance UK, a national alliance of organizations headquartered in the U.K., reported in February 2024 that over 3.5 million individuals in the U.K. are affected by rare conditions, with 1 in 17 experiencing such conditions sometimes during their life. Among the 7,000 recognized rare conditions, 70% impact children and with over 30% of these children succumbing to death before their fifth birthday due to these severe disorders. As such, the accelerating diagnoses of rare diseases is expected to push the adagen market forward.

Which Primary Segments of the Adagen Market Are Driving Growth and Industry Transformations?

The adagenmarket covered in this report is segmented –

1) By Product: Pre-filled; Vial

2) By Clinical Indication: Severe Combined Immunodeficiency (SCID); Other Rare Genetic Disorders

3) By End User: Hospitals And Healthcare Institutions; Specialty Clinics; Home Healthcare Services; Research Institutions

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Which Regions Are Key Players in the Growth of the Adagen Market?

North America was the largest region in the adagen market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the adagen market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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What Parameters Are Used to Define the Adagen Market?

Adagen is a brand name for pegademase bovine, an enzyme replacement therapy used to treat severe combined immunodeficiency (SCID) caused by adenosine deaminase deficiency. It is used for supporting immune function in individuals with SCID, helping to reduce the risk of life-threatening infections by replenishing the missing enzyme necessary for proper immune system development.

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