Future Outlook of the Antisense & RNAi Therapeutics Market: Growth, Trends, and Emerging Opportunities Explored
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What is the Expected Growth Rate of the Antisense & RNAi Therapeutics Market Based on Industry Projections?
The antisense & RNAi therapeutics market has grown rapidly. It is forecasted to rise from $1.75 billion in 2024 to $1.94 billion in 2025, reflecting a CAGR of 11.2%. Growth has been driven by increased research funding, advancements in technology, rising healthcare expenditure, an aging population, and economic expansion in emerging markets.
The antisense & RNAi therapeutics market is expected to witness rapid growth in the next few years, projected to reach $3.18 billion by 2029 at a compound annual growth rate (CAGR) of 13.1%. The growth during this period can be attributed to increased healthcare access, rising cancer prevalence, and growing demand for antisense and RNAi therapeutics in response to COVID-19. Major trends expected in the forecast period include research and development focused on RNA therapeutics for orphan diseases, the use of nanoparticles, the development of improved antisense and RNAi therapeutics, and collaborations with other companies for product innovation and revenue generation.
Which Macro and Microeconomic Factors Are Accelerating the Growth of the antisense & rnai therapeutics Market?
The rising prevalence of coronary artery diseases, neurodegenerative disorders, and infectious diseases is expected to drive the antisense & RNAi therapeutics market. RNA interference and antisense oligonucleotides are gene-suppressing treatments used to address various neurodegenerative conditions. According to the American Heart Association, the age-adjusted death rate from cardiovascular diseases increased to 233.3 per 100,000 in January 2024, showing a 4.0% rise from the previous year. Consequently, the growing number of neurodegenerative diseases and infectious diseases will contribute to the demand for antisense & RNAi therapeutics.
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What Companies Are At the Forefront of Innovation in the Antisense & RNAi Therapeutics Market?
Major companies operating in the antisense & RNAi therapeutics market include:
• Biogen Inc._x000D_
• Ionis Pharmaceuticals Inc._x000D_
• Alnylam Pharmaceuticals Inc._x000D_
• Arrowhead Pharmaceuticals Inc._x000D_
• Moderna Inc._x000D_
How Are Emerging Trends in Consumer Behavior Affecting the Antisense & RNAi Therapeutics Market?
Key players in the antisense and RNAi therapeutics market are forming strategic collaborations and partnerships to stay competitive. A strategic collaboration involves multiple companies working together to achieve shared goals. For example, in January 2023, Orbit Discovery Limited, a US-based peptide discovery company, partnered with SanegeneBio Inc., a UK-based developer of RNAi-based medicines. This collaboration focuses on identifying tissue-specific delivery mechanisms for RNA therapeutics to enhance gene knockdown efficiency. The partnership includes hit identification and cell-based internalization studies, allowing Sanegene to advance potential candidates using Orbit’s proprietary peptide discovery technology. Orbit’s platform enables rapid screening of large peptide libraries, expediting lead identification through affinity and functional screens.
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Which Segments Play a Crucial Role in the Expansion of the Antisense & RNAi Therapeutics Market?
The antisense & RNAi therapeutics market covered in this report is segmented –
1) By Technology: RNA Interference, Antisense RNA
2) By Route Of Administration: Intravenous Injections, Intra-dermal Injections, Other Delivery Methods
3) By Indication: Oncology, Cardiovascular Diseases (CVDs), Respiratory Disorders, Neurological Disorders, Infectious Diseases, Other Indications
Subsegments:
1) By RNA Interference (RNAi): Small Interfering RNA (siRNA), Short Hairpin RNA (shRNA), Dicer-substrate siRNA, MicroRNA (miRNA) Based Therapeutics
2) By Antisense RNA: Antisense Oligonucleotides (ASOs), Morpholino Oligomers, Locked Nucleic Acids (LNAs), Gapmer Antisense Oligonucleotides
What Regions Are Propelling Growth in the Antisense & RNAi Therapeutics Industry?
North America was the largest region in the antisense & RNAi therapeutics market in 2024. The regions covered in the antisense & RNAi therapeutics market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa
How Is the Antisense & RNAi Therapeutics Market Categorized and Defined in the Industry?
Antisense therapy refers to the selective, sequence-specific suppression of gene expression by single-stranded DNA oligonucleotides. Contrarily, RNA interference (RNAi) is activated by double-stranded RNA (dsRNA) and results in the sequence-specific mRNA degradation of single-stranded target RNAs.
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