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What are the Key Projections for the CAGR of the Breast Cancer Liquid Biopsy Market From 2025 to 2034?

There has been a swift expansion in the size of the breast cancer liquid biopsy market in recent years. The forecasted growth is from $0.78 billion in 2024 up to $0.90 billion in 2025, exhibiting a compound annual growth rate (CAGR) of 15.0%. The said growth during the historic period can be attributed to advancements in next-generation sequencing (ngs), the increasing occurrence of breast cancer, mounting demand for non-invasive diagnostic methods, an upsurge in the acceptance of personalized medicine, and augmented funding directed towards cancer research.

The market size for breast cancer liquid biopsy is predicted to experience substantial expansion in the coming years, eventually reaching a value of $1.56 billion by 2029 with a compound annual growth rate (CAGR) of 14.7%. The escalation in the projection period is due to advancements in liquid biopsy assays technology, the growing use of liquid biopsy for early cancer detection, rising need for real-time cancer monitoring, widespread applications in precision oncology, and increased funding in liquid biopsy research and development. The prediction period will see key trends including the incorporation of artificial intelligence into liquid biopsy analysis, progress in single-cell sequencing, the creation of multi-omics liquid biopsy platforms, enhancement in liquid biopsy sensitivity and specificity, and the use of digital pcr for highly accurate mutation identification.

What Major Innovations Are Driving the Accelerated Growth of the Breast Cancer Liquid Biopsy Market?

The rise in breast cancer incidences is likely to fuel the expansion of the breast cancer liquid biopsy market. Breast cancer, a cancer that originates in the breast cells, commonly in the lobules (milk-producing glands) or ducts (channels that transport milk to the nipple), is witnessing an upsurge due to various factors such as genetic predisposition, hormonal irregularities, aging population, changes in lifestyle, obesity, alcohol intake, physical inactivity, exposure to radiation, and environmental pollutants. A breast cancer liquid biopsy aids in the detection of circulating tumor DNA (ctDNA) or circulating tumor cells (CTCs) in the blood, thereby facilitating real-time disease monitoring. It assists in evaluating treatment response, spotting therapy resistance, and detecting genetic mutations for targeted therapies. For example, the American Cancer Society, a US-based charitable organization committed to cancer research, education, advocacy, and patient support, forecasts that the number of new breast cancer cases could escalate to 319,750 in 2025, an increase from 313,510 cases in 2024. Hence, the rising incidences of breast cancer are contributing to the growth of the breast cancer liquid biopsy market.

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What Are the Key Industry Players Leading the Charge in the Breast Cancer Liquid Biopsy Market’s Growth?

Major companies operating in the breast cancer liquid biopsy market are Johnson & Johnson Private Limited, Roche Diagnostics, Merck KGaA, Thermo Fisher Scientific, Siemens Healthineers, Agilent Technologies Inc., Illumina Inc., Sysmex Corporation, Qiagen N.V., Myriad Genetics Inc., NeoGenomics Laboratories, Guardant Health Inc., Twist Bioscience, Foundation Medicine Inc., Biodesix Inc., Menarini Silicon Biosystems, Datar Cancer Genetics, Abcam plc, OncoDNA SA, Genomic Health Inc., RainDance Technologies, Biocept Inc., Fluxion Biosciences Inc., Angle plc

How Are Market Trends and Shifts Impacting the Growth Trajectory of the Breast Cancer Liquid Biopsy Market?

Leading firms in the breast cancer liquid biopsy market are prioritizing the development of novel products like companion diagnostics. This facilitates personalized treatment procedures by spotting the patients apt for certain treatments. These diagnostics apply liquid biopsy techniques to identify biomarkers like genetic mutations, circulating tumor DNA (ctDNA), or protein expressions that show a response to treatment. As an example, in January 2023, Guardant Health Inc., a US-derived biotechnology firm, was granted clearance by the Food and Drug Administration (FDA) for its Guardant360 CDx liquid biopsy examination as a companion diagnostic for ORSERDU (elacestrant), a Menarini Group’s treatment for advanced or metastatic breast cancer patients carrying ESR1 mutations. This approval sanctions oncologists to utilize the test for thorough genomic profiling, pinpointing patients who might profit from this specific therapy. It signifies the maiden U.S. Food and Drug Administration (FDA) approval of Guardant Health in breast cancer and amplifies its contribution in precision oncology.

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Which Growth-Oriented Segments of the Breast Cancer Liquid Biopsy Market Are Leading the Industry’s Development?

The breast cancer liquid biopsy market covered in this report is segmented –

1) By Product: Consumables, Kits

2) By Biomarkers: Extracellular Vesicles (EVs), Cell-free DNA (cfDNA), Circulating Tumor RNA (ctRNA), Circulating Tumor Cells (CTCs), Cell-free RNA (cfRNA), Other Biomarkers

3) By Application: Early Detection Or Screening, Diagnosis, Other Applications

4) By End Users: Laboratories, Hospitals, Physician Laboratories, Reference Laboratories, Public Health Laboratories, Research Institutes, Small Molecular Laboratories, Pathology Laboratories

Subsegments:

1) By Consumables: Reagents, Polymerase Chain Reaction (PCR) Assays, Sequencing Panels, Sample Collection Tubes

2) By Kits: DNA-based Liquid Biopsy Kits, RNA-based Liquid Biopsy Kits, Multi-marker Liquid Biopsy Kits

What Regions Are Influencing the Dynamics of the Breast Cancer Liquid Biopsy Market?

North America was the largest region in the breast cancer liquid biopsy market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the breast cancer liquid biopsy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

What Key Elements Shape the Definition of the Breast Cancer Liquid Biopsy Market?

A breast cancer liquid biopsy is a minimally invasive test that detects and analyzes tumor-derived materials in a patient’s blood or other bodily fluids. It provides valuable insights into the presence, progression, and genetic profile of breast cancer without requiring a traditional tissue biopsy.

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