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What fueled the previous growth in the cardiac tissue engineering market?

In recent times, the market size for cardiac tissue engineering has seen substantial growth. The market is projected to expand from $0.67 billion in 2024 to $0.81 billion in 2025, with a compound annual growth rate (CAGR) of 19.7%. The growth observed in the past period is mainly due to a shortage of organ donors, increased instances of cardiovascular diseases, breakthroughs in biomaterials, surged funding in regenerative medicine, high demand for personalized medicine, progress in bioreactor systems, heightened government support for biomedical research, and a growing trend towards minimally invasive therapies.

What will be the cardiac tissue engineering market size in the future?

The market for cardiac tissue engineering is set to witness a significant rise in the coming years, with a projected value of $1.64 billion by 2029, marking a compound annual growth rate (CAGR) of 19.4%. This anticipated expansion during the forecast period can be linked to factors such as evolving demand for tailored cardiac treatments, a growing emphasis on bioengineered heart tissues, widening applications of regenerative medicine, enhanced partnerships between biotech companies and academic institutions, increased funding in preclinical testing platforms, and a growing prevalence of chronic heart conditions. Notable trends expected in the forecast phase include the inclusion of AI in tissue engineering, progress in nanotechnology-based scaffolds, creation of biodegradable hydrogels, evolution in 3D bioprinting precision, adoption of bioreactors for tissue maturation, and the application of gene editing to enhance cardiac cells.

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What main drivers are fueling expansion in the cardiac tissue engineering market?

An upward trajectory in cardiovascular disease cases is anticipated to fuel the expansion of the cardiac tissue engineering market. This crossover field is centered on creating either biological or bioengineered assemblies to fix, rejuvenate, or substitute the injured cardiac tissue. The surge in cardiovascular disease incidents is largely a consequence of detrimental lifestyle factors, including unhealthy eating, lack of exercise, smoking habits, and escalating rates of obesity and diabetes. Cardiac tissue engineering comes into play in cardiovascular diseases by fabricating biomaterials, cell-based treatments, and bioengineered tissues, which aid in mending or rejuvenating injured heart muscles and reinstating cardiac function. For example, data from the Centers for Disease Control and Prevention, a US government agency, showed that by May 2023, the prevalence of coronary heart disease among adult females aged 18 and above rose marginally to 3.7% in 2023 from 3.6% in 2022. Therefore, the proliferating cases of cardiovascular diseases are accelerating the expansion of the cardiac tissue engineering market.

What key areas define the segmentation of the global cardiac tissue engineering market?

The cardiac tissue engineering market covered in this report is segmented –

1) By Product: Heart Valves, Vascular Grafts

2) By Material: Stem Cells, Scaffolds

3) By Application: Myocardial Infarction, Heart Valve Repair Or Replacement, Congenital Heart Disease Treatment, Other Applications

4) By End Users: Hospitals And Clinics, Academic And Research Institutes, Other End Users

Subsegments:

1) By Heart Valves: Bioprosthetic Heart Valves, Mechanical Heart Valves, Tissue-Engineered Heart Valves

2) By Vascular Grafts: Synthetic Vascular Grafts, Biologic Vascular Grafts, Tissue-Engineered Vascular Grafts

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Who are the dominant players expanding their reach in the cardiac tissue engineering market?

Major companies operating in the cardiac tissue engineering market are Biotronik SE & Co. KG, Terumo Corporation, Artivion Inc., Tissue Regenix Group plc, PromoCell GmbH, Xeltis AG, Carmat S.A., Bioheart Inc., Prellis Biologics Inc., Cytograft Tissue Engineering Inc., Avery Therapeutics Inc., Vascudyne Inc., Auto Tissue Berlin GmbH, CorMatrix Cardiovascular Inc., Humacyte Inc., BioCardia Inc., Osiris Therapeutics Inc., StemCells Inc., ViroMed Co. Ltd., Cardio3 Biosciences

What key trends are currently impacting the cardiac tissue engineering market’s development?

Major firms in the cardiac tissue engineering industry are focusing on technological advancements, such as 3D-engineered muscle tissues, to fine-tune the precision and effectiveness of drug discovery in providing optimal treatments for cardiovascular conditions. 3D-engineered muscle tissues, bioengineered constructs, reproduce human muscle’s structural and functional characteristics typically utilized for drug testing and disease modeling. For example, in July 2022, the US-based biotechnology company, Curi Bio Inc., introduced the Mantarray platform. This platform provides a human-relevant 3D heart and skeletal engineered muscle tissue (EMT) contractility analysis and uses cutting-edge tissue culture techniques to produce highly functional muscle tissues mimicking the mechanical properties and behavior of natural muscle, thus providing a more precise model for drug testing. The purpose of this technology is to expedite the process of creating therapeutic solutions by enabling researchers to examine muscle contraction, the response to stimuli, and cellular-level disease modeling.

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Which regions are emerging as leaders in the cardiac tissue engineering market?

North America was the largest region in the cardiac tissue engineering market in 2024. The regions covered in the cardiac tissue engineering market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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