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What is the Predicted Annual Growth Rate of the Cartilage Degeneration Market Over the Coming Decade?

There has been a noticeable surge in the size of the cartilage degeneration market in the recent past. Its expected growth trajectory is from $12.63 billion in 2024 to $13.4 billion in 2025, sustaining a compound annual growth rate (CAGR) of 6.2%. The noted escalation in the previous period is due to factors such as the aging population, joint injuries, obesity spread, sports-related injuries, and restricted self-repair capabilities.

The market for cartilage degeneration is set to observe significant growth in the upcoming years. Projections estimate that by 2029, it will expand to $16.62 billion, with a compound annual growth rate (CAGR) of 5.5%. The anticipated growth during this period can be credited to advancements in regenerative medicine, the introduction of biologic injections, development of tissue engineering solutions, precision medicine, and the use of robotics in surgery. Notable trends expected during the forecast period involve the use of stem cell therapies, the integration of 3D printing in the orthopedics field, gene therapy aimed at cartilage repair, the customization of rehabilitation programs, and the application of telemedicine for patient follow-up care.

What Market Dynamics Are Playing a Key Role in Accelerating the Growth of the Cartilage Degeneration Market?

The cartilage degeneration market’s projected expansion is largely attributed to the escalating rates of obesity. Understood as a health condition marked by excessive bodily fat accumulation to dangerous levels, obesity is a known catalyst and accelerator for cartilage degradation. It boosts both cartilage compression forces and inflammatory cytokine levels. Its impact extends to causing significant alterations to the entire knee joint structure, such as abnormal joint loading, malalignment of joints, and weakened muscles. For instance, the Government Digital Service of the UK reported in May 2023 that in 2021-2022, approximately 63.8% of adults aged 18 and above were either overweight or obese, marking a slight increase from the previous year’s 63.3%. Nearly 25.9% of these adults were classified as obese, signifying a 25.2% increment since 2020-2021. Consequently, these rising obesity levels contribute to the robust growth of the cartilage degeneration market.

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What Are the Major Players Making an Impact in the Cartilage Degeneration Market’s Growth?

Major companies operating in the cartilage degeneration market report are Johnson & Johnson Services Inc., MEDIPOST Co. Ltd., Medtronic PLC, Stryker Corporation, Zimmer Biomet Holdings Inc., Smith and Nephew PLC, B Braun Melsungen AG, Osiris Therapeutics Inc., Arthrex Inc., Conmed Corporation, Orthocell Ltd., Bioventus LLC, Aesculap Inc., Vericel Corporation, Anika Therapeutics Inc., Geistlich Pharma AG, MatTek Corporation, Breg Inc., Isto Biologics Inc., OrthoTrophix LLC, CellGenix GmbH, CartiHeal Inc., Cayenne Medical Inc., Collagen Solutions PLC, Regentis Biomaterials Ltd., Histogen Inc., BioTime Inc., CollPlant Holdings Ltd.

Which Upcoming Trends Are Set to Influence the Cartilage Degeneration Market’s Path Forward?

Leading firms in the cartilage degeneration market are introducing innovative products like Agili-C, which aid in bone remodeling and cartilage regeneration. Agili-C, a cell-free, readily available implant, is utilized for repairing cartilage and osteochondral defects in both traumatic and osteoarthritic joints. In July 2023, CartiHeal Ltd., a medical device company based in Israel, declared its initial commercial implantation of Agili-C. The implant aims to promote the natural regeneration of articular cartilage and subchondral bone, instead of depending on cells or growth factors. The implant, made of natural calcium carbonate – aragonite, originates from coral exoskeletons. It prompts chondrocytes from the adjacent cartilage to infiltrate the scaffold, leaving an extracellular matrix behind. This validation augments the value of the implant, offering patients and healthcare providers peace of mind regarding its safety and effectiveness as a treatment option.

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How Are the Key Segments of the Cartilage Degeneration Market Impacting Its Expansion and Revenue Streams?

The cartilage degeneration market covered in this report is segmented –

1) By Procedure: Joint Replacements, Chondroplasty, Osteochondral Transplants, Microfracture, Meniscus Transplants, Cell-Based Cartilage Resurfacing, Autologous Chondrocyte Implantation, Other Procedures

2) By Application: Knee, Hip, Other Applications

3) By End User: Hospitals And Specialty Clinics, Ambulatory Surgical Centers, Academic And Research Institutes

Subsegments:

1) By Joint Replacements: Knee Replacement (Partial, Total), Hip Replacement (Partial, Total), Shoulder Replacement (Total, Reverse), Other Joints (Ankle, Elbow, Wrist)

2) By Chondroplasty: Radiofrequency Ablation Chondroplasty, Mechanical Chondroplasty, Thermal Chondroplasty, Arthroscopic Chondroplasty

3) By Osteochondral Transplants: Autografts (OATS), Allografts (Fresh Osteochondral Allografts), Synthetic Implants

4) By Microfracture: Traditional Microfracture, Augmented Microfracture (with scaffolds or matrix implants)

5) By Meniscus Transplants: Allograft Meniscus Transplantation (Cryopreserved, Fresh Frozen), Synthetic Meniscus Implants

6) By Cell-Based Cartilage Resurfacing: Autologous Cell-Based Therapy, Allogeneic Cell-Based Therapy, Stem Cell-Based Cartilage Repair

7) By Autologous Chondrocyte Implantation (ACI): First-Generation ACI, Second-Generation ACI, Third-Generation ACI (MACI)

8) By Other Procedures: Arthroscopic Debridement, Osteotomy, Cartilage Repair Using Synthetic Scaffolds, Injection-Based Therapies (Hyaluronic Acid, PRP, Stem Cell Injections)

What Regions Are Steering Growth in the Cartilage Degeneration Sector?

North America was the largest region in the cartilage degeneration market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the cartilage degeneration market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

How Is the Cartilage Degeneration Market Classified and Defined in Market Analysis?

Cartilage degeneration refers to the gradual deterioration or breakdown of cartilage tissue, a smooth, flexible connective tissue covering the ends of bones in joints. Cartilage is a cushion that allows for smooth joint movement by reducing bone friction. Cartilage degeneration leads to pain, stiffness, and decreased joint function.

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