2025 Market Reports Update: Market Size Forecasts to 2034, Key Trends, Leading Players, and Top Regions – Get Ahead of the Competition Today!

What External and Internal Drivers Are Contributing to the Growth of theCartilage Degeneration Market?

The rise in obesity rates is projected to drive the growth of the cartilage degeneration market. Obesity, a condition characterized by excessive body fat, can accelerate cartilage degeneration by increasing joint stress and promoting inflammatory processes. It also leads to structural changes in the knee joint, such as abnormal loading, misalignment, and muscle weakness. For instance, in May 2023, the Government Digital Service, a UK government agency, reported that 63.8% of adults over 18 were overweight or obese in 2021-2022, up from 63.3% the previous year. Additionally, 25.9% of adults were classified as obese, an increase of 25.2% from 2020 to 2021. Therefore, the increasing prevalence of obesity is expected to drive growth in the cartilage degeneration market.

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#What is the Growth Potential of the Cartilage Degeneration Market, and How Will It Perform by 2034?

The cartilage degeneration market has grown consistently in recent years. It will grow from $12.63 billion in 2024 to $13.4 billion in 2025, at a CAGR of 6.2%. Historical growth has been driven by the aging population, increasing joint injuries, obesity-related stress on joints, athletic injuries, and the limited self-healing capacity of cartilage.

The cartilage degeneration market is projected to see strong growth, reaching $16.62 billion by 2029 at a CAGR of 5.5%. The growth is driven by advancements in regenerative medicine, biologic injections, tissue engineering, and robotics-assisted surgery. Major trends in this space include stem cell therapies, gene therapy for cartilage repair, and the use of 3D printing in orthopedics.

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Which Upcoming Market Trends and Innovations Are Set to Influence theCartilage Degeneration Market’s Path Forward?

Innovations in the cartilage degeneration market include the Agili-C implant, which supports cartilage and bone regeneration without relying on cells or growth factors. In July 2023, CartiHeal Ltd. completed the first commercial use of Agili-C, made from coral-derived aragonite. It promotes natural cartilage regeneration and reassures users of its safety and effectiveness.

Who Are the Dominant Market Players Pushing the Boundaries of theCartilage Degeneration Market?

Major companies operating in the cartilage degeneration market report are Johnson & Johnson Services Inc., MEDIPOST Co. Ltd., Medtronic PLC, Stryker Corporation, Zimmer Biomet Holdings Inc., Smith and Nephew PLC, B Braun Melsungen AG, Osiris Therapeutics Inc., Arthrex Inc., Conmed Corporation, Orthocell Ltd., Bioventus LLC, Aesculap Inc., Vericel Corporation, Anika Therapeutics Inc., Geistlich Pharma AG, MatTek Corporation, Breg Inc., Isto Biologics Inc., OrthoTrophix LLC, CellGenix GmbH, CartiHeal Inc., Cayenne Medical Inc., Collagen Solutions PLC, Regentis Biomaterials Ltd., Histogen Inc., BioTime Inc., CollPlant Holdings Ltd.

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What Are the Core Segments of the Cartilage Degeneration Market, and How Do They Contribute to Growth?

The cartilage degeneration market covered in this report is segmented –

1) By Procedure: Joint Replacements, Chondroplasty, Osteochondral Transplants, Microfracture, Meniscus Transplants, Cell-Based Cartilage Resurfacing, Autologous Chondrocyte Implantation, Other Procedures

2) By Application: Knee, Hip, Other Applications

3) By End User: Hospitals And Specialty Clinics, Ambulatory Surgical Centers, Academic And Research Institutes

Subsegments:

1) By Joint Replacements: Knee Replacement (Partial, Total), Hip Replacement (Partial, Total), Shoulder Replacement (Total, Reverse), Other Joints (Ankle, Elbow, Wrist)

2) By Chondroplasty: Radiofrequency Ablation Chondroplasty, Mechanical Chondroplasty, Thermal Chondroplasty, Arthroscopic Chondroplasty

3) By Osteochondral Transplants: Autografts (OATS), Allografts (Fresh Osteochondral Allografts), Synthetic Implants

4) By Microfracture: Traditional Microfracture, Augmented Microfracture (with scaffolds or matrix implants)

5) By Meniscus Transplants: Allograft Meniscus Transplantation (Cryopreserved, Fresh Frozen), Synthetic Meniscus Implants

6) By Cell-Based Cartilage Resurfacing: Autologous Cell-Based Therapy, Allogeneic Cell-Based Therapy, Stem Cell-Based Cartilage Repair

7) By Autologous Chondrocyte Implantation (ACI): First-Generation ACI, Second-Generation ACI, Third-Generation ACI (MACI)

8) By Other Procedures: Arthroscopic Debridement, Osteotomy, Cartilage Repair Using Synthetic Scaffolds, Injection-Based Therapies (Hyaluronic Acid, PRP, Stem Cell Injections)

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What Regions Are Dominating the Cartilage Degeneration Market Growth?

North America was the largest region in the cartilage degeneration market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the cartilage degeneration market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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