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How has the cell and gene therapy market grown over the years?

The dimensions of the cell and gene therapy market have seen a rapid expansion in the past few years. The market size is projected to rise from $12.01 billion in 2024 to $15.48 billion in 2025, marking a compound annual growth rate (CAGR) of 28.9%. The remarkable growth during the historic period is a result of factors such as growing investments in cell and gene therapies, proliferation in research and development efforts, breakthroughs in cancer drug discovery, ascension in public-private associations, sturdy economic progression in developing markets, increased spending in healthcare, and the escalation in financial outlays for pharmaceutical R&D.

What Is the forecasted market size and growth rate for the cell and gene therapy market?

In the coming years, the cell and gene therapy market is set to experience swift expansion, projected to reach $29.15 billion in 2029 at a compound annual growth rate (CAGR) of 17.1%. The predicted expansion during this period is due to a confluence of factors such as the escalating prevalence of cancer and chronic diseases, the increasing number of older adults, a greater emphasis on cell and gene therapy, and a rise in healthcare spending. Key trends forecasted for this period encompass emphasis on progressive treatments like chimeric antigen receptor (CAR) T-cell therapy, dedication towards diverse research initiatives and securing funding, execution of key collaborations for the assimilation of cutting-edge technology, focus on crafting gene or genome editing tools particularly CRISPR, acquisition or partnership with rival companies, augmenting the quantity of pipeline studies to advance cell and gene therapies, and investment in the expansion of manufacturing premises.

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What are the major factors driving growth in the cell and gene therapy market?

The continuous contribution of investments and the amalgamation in cell and gene therapies significantly fueled the cell and gene therapy (CGT) market’s growth. Recognizing the CGT market’s potential, 16 of the top 20 biopharmaceutical firms in terms of revenue incorporated CGT products into their offerings. For example, the BioIndustry Association (BIA), a UK-based entity representing the biotech and life sciences industry, stated that in 2023, over 55% of the venture capital funds obtained by European companies were secured by UK cell and gene therapy firms. The UK typically accounts for approximately one-third of all VC investments in life sciences throughout Europe, which underscores the robust status of its cell and gene therapy sector. Consistent investments and consolidation in CGT production capacity contributed to a surge in production capabilities, thus fostering market growth. For instance, Purespring Therapeutics, a UK-based biotech firm, received $105 million funding in October 2024 to back the development of gene therapies for kidney diseases, such as running a phase 1/2 trial for an experimental treatment for immunoglobulin A nephropathy (IgAN). Purespring employs adeno-associated viruses (AAVs) to deliver its gene therapies to the body.

What key areas define the segmentation of the global cell and gene therapy Market?

The cell and gene therapy market covered in this report is segmented –

1) By Product: Cell Therapy, Gene Therapy

2) By Application: Oncology, Neurological Disorders, Other Applications

3) By End User: Hospitals, Ambulatory Surgical Centers, Cancer Care Centers, Wound Care Centers, Other End-Users

Subsegments:

1) By Cell Therapy: Autologous Cell Therapy, Allogeneic Cell Therapy, Stem Cell Therapy, CAR-T Cell Therapy

2) By Gene Therapy: Viral Vector-Based Gene Therapy, Non-Viral Vector-Based Gene Therapy, Genome Editing Technologies, Antisense Oligonucleotide Therapy

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What are the top market players propelling the growth of the cell and gene therapy industry?

Major companies operating in the cell and gene therapy market include Biogen Inc., Novartis AG, Gilead Sciences, Ionis Pharmaceuticals Inc., Alnylam Pharmaceuticals Inc., ArrowHead Pharmaceuticals Inc., Spark Therapeutics, Bluebird Bio Inc., RegenexBio, Mesoblast Limited, Biocon, Cipla, Stempeutics Research Pvt. Ltd., EdiGene Inc., Immunochina, Takara Bio, Daiichi Sankyo Company, Ultragenyx Pharmaceutical Inc, Mitsubishi Tanabe Pharma, Oxford Biomedica plc, Santen Pharmaceutical Co., Therapeutic Innovation Australia, Merck, GenScript, Cellular Biomedicine Group, GE Healthcare, inStem, Lonza, Nikon CeLL innovation Co. Ltd., Bristol-Myers Squibb, Amgen, Pfizer, Kite Pharma, Oxford BioTherapeutics, Freeline Therapeutics, PsiOxus Therapeutics, Herantis Pharma Plc, AstraZeneca

What are the key trends shaping the future of the cell and gene therapy market?

The cell and gene therapy (CGT) market is being significantly impacted by the advancement of Chimeric antigen receptor (CAR) T-cell therapy. This innovative therapy merges cell and gene therapy, involving the extraction of T cells from the patient’s bloodstream and their subsequent genetic modification to produce altered receptors, termed as chimeric antigen receptors (CARs), on their exteriors. These genetically restructured T cells, with their unique receptor structures, are then reintroduced into the patient’s body. The specialized receptors on these T cells then target the surface antigen of the cancer cells, culminating in the eradication of tumor cells. For example, in June 2022, Bristol-Myers Squibb Company, an American pharmaceutical corporation, obtained approval from the US Food and Drug Administration (US FDA) for their CAR T cell therapy Breyanzi, intended for use in adult patients suffering from large B-cell lymphoma (LBCL) including diffuse large B-cell lymphoma. Breyanzi, a unique CAR T cell therapy, utilizes the patient’s re-engineered T cells and reintroduces them into the body through a single-session treatment.

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What regions are dominating the cell and gene therapy market growth?

North America was the largest region in the cell and gene therapy market in 2024. The regions covered in the cell and gene therapy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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