What Will The Checkpoint Inhibitors Market Look Like In 2023?
The Business Research Company’s global market reports are now updated with the latest market sizing information for the year 2023 and forecasted to 2032
The Business Research Company’s checkpoint inhibitors market report forecasts the checkpoint inhibitors market size to grow to $49.12 Billion by 2027, with a CAGR (compound annual growth rate) of more than 15%.
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Checkpoint Inhibitors Market Size Forecast
The global checkpoint inhibitors market is expected to grow from $23.93 billion in 2022 to $27.83 billion in 2023 at a compound annual growth rate (CAGR) of 16.3%. The Russia-Ukraine war disrupted the chances of global economic recovery from the COVID-19 pandemic, at least in the short term. The war between these two countries has led to economic sanctions on multiple countries, a surge in commodity prices, and supply chain disruptions, causing inflation across goods and services and affecting many markets across the globe. The checkpoint inhibitors market is expected to grow from $49.12 billion in 2027 at a CAGR of 15.3%.
North America held the largest checkpoint inhibitors market share, and Middle East was the fastest-growing region in 2022.
Key Checkpoint Inhibitors Market Driver – Rise In The Number Of Cancer Cases Globally
For instance, in January 2022, according to the American Cancer Society, there will likely be 1.9 million new cancer diagnoses and 609,360 cancer-related deaths in the US, or roughly 1,670 fatalities every day. The four most common types of cancer worldwide are lung, prostate, bowel, and female breast cancer, accounting for 43 percent of all new cancer cases. Checkpoint inhibitors targeting the checkpoints are very helpful as cancer therapies. Therefore, the rise in cancer incidence rates globally is anticipated to boost demand for checkpoint inhibitors market.
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Key Checkpoint Inhibitors Market Trend – developing advanced technologies
Major companies in the checkpoint inhibitor market are forming partnerships or collaborations for the development of advanced technologies such as bifunctional fusion proteins or Y-trap. Most patients with cancer do not respond to immune checkpoint inhibitors. To make immunotherapies more effective, a group of researchers has developed the bifunctional fusion protein or Y-trap. This drug is created by fusing a receptor for a protein called TGF-beta that targets checkpoint proteins such as PD-L1 or CTLA-4. Y- Trap targets both a checkpoint inhibitor and TGF-beta and gives a more effective way to block the immune suppression and destroys the cancer cells. Merck, a prominent science and technology group, and GSK, a research-based global healthcare company, have announced that they have entered into a global strategic partnership to jointly create and market M7824 (bintrafusp alfa). M7824 is an investigational bi-functional fusion protein immunotherapy that is currently in clinical research, including possible registration trials, for various difficult-to-treat cancers. This includes a Phase II study to investigate M7824 compared to pembrolizumab as a first-line treatment in patients with PD-L1 expressing advanced non-small cell lung cancer (NSCLC). In another instance, in June 2020, Targovax, a Norway-based biotechnology company that develops immune activators for targeting solid tumors, entered into a collaboration with Leidos’ Explorations in Global Health (ExGloH) division for evaluating the potential of using ONCOS, a Targovax’s clinical programme of oncolytic adenoviruses, as a vector to encode Microtide™ checkpoint inhibitor peptides.
Checkpoint Inhibitors Market Segment
1) By Drug: PD-1 Inhibitors, PD-L1 Inhibitors, CTLA-4, Chimeric Antigen Receptor T-Cells, Other Drugs
2) By Application: Lung Cancer, Renal Cancer, Blood Cancer, Bladder Cancer, Melanoma, Other Applications
3) By End-Users: Hospitals Pharmacies, Retail Pharmacies, Online Pharmacies
Checkpoint Inhibitors Market Major Players and Strategies
Major players in the checkpoint inhibitors market are AstraZeneca PLC., Bristol-Myers Squibb Company, Merck & Co., Inc., Roche Holding AG, Pfizer, Incyte Corporation, Novartis AG, and NewLink Genetics Corporation.
In June 2020, Targovax, a Norway-based biotechnology company, entered into a collaboration with the Explorations in Global Health (ExGloH) division of Leidos to evaluate the potential of using ONCOS, a Targovax’s clinical programme of oncolytic adenoviruses, as a vector to encode microtide checkpoint inhibitor peptides. The Explorations in Global Health (ExGloH) division of Leidos has created a specific, proprietary portfolio of microbially-derived peptides called MicrotideTM that act as immune checkpoint inhibitors. Leidos is a US-based company that deals with defense, aviation, information technology, and biomedical research.
The Checkpoint Inhibitors Global Market Report 2023 covers regional data on checkpoint inhibitors market size, checkpoint inhibitors market trends and drivers, opportunities, strategies, and checkpoint inhibitors market competitor analysis. The countries covered in the checkpoint inhibitors market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, the UK, and the USA, and the major seven regions are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, the Middle East, and Africa.
Checkpoint inhibitors refer to an immunotherapy strategy that prevents immune checkpoint proteins from forming interactions with other proteins. Because of this, the T cells are able to destroy cancer cells because the “off” signal is not sent. One such medication works against the checkpoint protein CTLA-4.
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