Denosumab Market Insights: In-Depth Look at Growth Trends, Market Size, and Opportunities for 2025-2034
Discover trends, market shifts, and competitive outlooks for the denosumab industry through 2025-2034 with The Business Research Company’s reliable data and in-depth research
What Is the Current and Projected Market Size of the Denosumab Market Through 2034?
In recent years, the denosumab market has seen substantial growth. The market, valued at $3.27 billion in 2024, is expected to rise to $3.7 billion in 2025, with a compound annual growth rate (CAGR) of 13.1%. The surge in growth during the historic period is a result of several factors, such as advancements in clinical research and trials, FDA approvals and regulatory milestones, increased awareness about bone health, along with strategic alliances and marketing drives.
In the coming years, the market size of denosumab is projected to undergo swift expansion. It is anticipated to escalate to $5.59 billion by 2029, with a compound annual growth rate (CAGR) of 10.9%. The propelling factors for growth in this projected timeframe include the increasing incidents of bone metastases, the development in cancer therapies, the prevalence of osteoporosis, heightened osteoporosis awareness, and regulation approval for new indications. Notable trends during the forecast period encompass strategic collaborations and alliances, digital health solutions integration, broadened indications and clinical applications, and progress in biosimilar creation.
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What External and Internal Drivers Are Contributing to the Growth of the Denosumab Market?
The escalated occurrence of osteoporosis is anticipated to boost the development of the denosumab market. Essentially, osteoporosis is a health condition where the strength of bones decreases, leading to reduced bone density and a heightened possibility of fractures. Denosumab is employed to mitigate osteoporosis, by halting bone absorption via RANK ligand targeting. For example, data from the Canadian Longitudinal Study on Aging released by the National Center for Biotechnology Information, a U.S. government agency, in September 2023, indicated that the occurrence of osteoporosis diagnosed by physicians stood at 12.7%, while DXA-validated osteoporosis was at 5.9% among elderly adults residing in the community. Furthermore, a cross-sectional study conducted by Buttros and his team showed that the occurrence of osteoporosis in postmenopausal women aged between 40 to 75, diagnosed using bone mineral density (BMD) evaluations, was at 24.6%. As such, the rising occurrence of osteoporosis is spurring the expansion of the denosumab market.
What Segment Types Define the Denosumab Market Structure?
The denosumab market covered in this report is segmented –
1) By Drug Classification: Prolia, Xgeva, Others
2) By Type: 60 mg, 120 mg
3) By End-Users: Hospitals, Homecare, Specialty Clinics, Ambulatory Surgical Centers
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Which Geographic Areas Hold the Strongest Growth Potential in the Denosumab Market?
North America was the largest region in the denosumab market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the denosumab market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
What Long-Term Trends Are Transforming the Competitive Landscape of the Denosumab Market?
Prominent firms in the denosumab market are ramping up their efforts to introduce innovative solutions, for instance, first-line therapies for osteoporosis, in a bid to secure a competitive advantage. The term “first-line treatment for osteoporosis” signifies the initial or prime therapeutic strategy suggested by healthcare practitioners for managing osteoporosis patients. Take for example, in November 2022, China’s Boan Biotech obtained approval from the National Medical Products Administration (NMPA) for its denosumab biosimilar, Boyoubei, becoming the debut Chinese firm to create a denosumab injection. The firm is also devising strategies for its introduction in markets beyond China, which include Europe and the United States, with an eye for global distribution. In several treatment guidelines, this drug has been advised as a first-line therapy for osteoporosis. The pharmaceutical holds the promise to substantially diminish the probability of hip, non-vertebral, and vertebral fractures in this category of patients. More so, Boyoubei stands as the world’s first biosimilar to Prolia (the original denosumab) with marketing approval.
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What Is the Definition of the Denosumab Market?
Denosumab is a monoclonal antibody used to treat bone-related conditions, particularly osteoporosis and bone metastases. It works by inhibiting osteoclast formation, decreasing bone resorption, increasing bone mineral density, and reducing the risk of fracture.
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