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How has the g-protein coupled receptors market size evolved in recent years?

In recent times, the G-protein coupled receptors market has seen substantial growth. The forecast suggests the market will expand from its $3.2 billion value in 2024 to a worth of $3.41 billion in 2025, marking a compound annual growth rate (CAGR) of 6.6%. The growth during the historical period has been driven by advancements in drug discovery, FDA approvals, genomic discoveries, the emergence of new markets, market consolidation, and an increasing aging population.

What are the predictions for the g-protein coupled receptors market size in the coming years?

In the coming years, the market size for G-protein coupled receptors is projected to experience robust growth, reaching $4.46 billion in 2029. This represents a compound annual growth rate (CAGR) of 7.0%. The expansion during the forecast period can be ascribed to factors such as personalized medicine, heightened focus on rare illnesses, application of artificial intelligence in drug discovery, patient-centered drug development, as well as environmental and social determinants. Additionally, the growth of the biosimilar market is a contributing factor. Key trends expected to shape the forecast period are advancements in biotechnology, escalated investments in research and development, technological innovations, collaborations/partnerships, and digital therapeutics.

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What key factors are fueling the growth of the g-protein coupled receptors market?

The G-protein-coupled receptors market is set to expand, driven by the escalating incidence of cancer. Cancer is a disease where unusual cells can affect adjacent tissues and expand unchecked. The lymphatic and vascular systems serve as additional pathways for cancer cells to proliferate. The key features of cancer like proliferative signaling, replicative immortality, evasion of growth restrictions, resistance to programmed cell death, and the triggering of invasion and metastasis, are all regulated by GPCRs. For example, data from the American Cancer Society, a professional organizations company based in the US, showed that with 1,958,310 new cancer diagnoses in 2023 — a jump from the approximately 1.9 million new cases in 2022 — cancer’s increasing prevalence is steering the growth of the G-protein-coupled receptors market.

How is the global g-protein coupled receptors market divided into key segments?

The G-protein coupled receptors market covered in this report is segmented –

1) By Product: Cell Lines, Detection Kits, Cell Culture Reagents, Ligands

2) By Assay: CAMP Functional Assays, Calcium Functional Assays, β-Arrestin Functional Assays, Radioligand Binding And GTPγS Functional Assays, Internalization Assays, Trafficking Assays

3) By Applications: Cancer Research, CNS Research, Metabolic Research, Cardiovascular Research, Inflammation Research, Respiratory Research, Other Applications

Subsegments:

1) By Cell Lines: GPCR-Expressing Cell Lines, Stable And Transient Cell Lines

2) By Detection Kits: ELISA Kits, High-Throughput Screening Kits, Reporter Gene Assays

3) By Cell Culture Reagents: Media And Supplements, Transfection Reagents, Growth Factors

4) By Ligands: Agonists, Antagonists, Inverse Agonists

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Who are the key firms paving the way for growth in the g-protein coupled receptors market?

Major companies operating in the G-protein coupled receptors market include Pfizer Inc., Roche Holding AG, AbbVie Inc., Bayer AG, Novartis International AG, Sanofi SA, Bristol-Myers Squibb Company, AstraZeneca Plc, GlaxoSmithKline Plc, Danaher Corporation, Takeda Pharmaceutical Company Limited, Eli Lilly and Company, Merck KGaA, Boehringer Ingelheim, Teva Pharmaceutical Industries Ltd., Daiichi Sankyo Company Limited, Thermo Fisher Scientific Inc., Perkin Elmer Inc., Qiagen N.V., Bio-Techne Corporation, Abcam PLC, Cara Therapeutics Inc., Sosei Heptares Ltd., Eurofins DiscoverX Corporation, Crinetics Pharmaceuticals Inc., Domain Therapeutics SA, Addex Pharmaceuticals Ltd., Escient Pharmaceuticals Inc., Structure Therapeutics, Septerna

Which trends are expected to transform the g-protein coupled receptors market?

A significant trend emerging in the G-protein-coupled receptor (GPCR) market is the investment in the enhancement of GPCR screening and antibody innovation. Leading players in GPCR are keen on securing investments to aid the creation of drugs and medical technologies associated with GPCR-oriented diseases. For example, in February 2023, LifeArc Ventures, a venture capital organization based in the UK, infused $16 million into Maxion Therapeutics, a drug discovery firm also in the UK. This funding aims to expedite the progression of antibody treatments targeting ion channels and GPCR-driven conditions by utilizing their proprietary KnotBody technology. KnotBody’s platform facilitates the discovery of biologicals addressing ion channels and GPCRs through the use of naturally existing cysteine-rich mini proteins. Furthermore, Septerna Inc., a biotech company situated in the US, announced their inception and a Series A funding amounting to $100 million. This financing will be channelled towards developing their burgeoning pipeline of GPCR-oriented medication programmes, driven by the Native Complex Platform and spanning several therapeutic areas.

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What regions are contributing significantly to the growth of the g-protein coupled receptors market?

North America was the largest region in the G-protein coupled receptors market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the G-protein coupled receptors market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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