Pharmaceuticals

Strong CAGR to Propel in the Gene Silencing Market and Beyond upto $10.95 Billion by 2029

June 11, 2025 by Marketing Posting

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#What is the Anticipated CAGR of the Gene Silencing Market, and What Factors Will Drive It?#_x000D_

In recent times, the market size for gene silencing has seen rapid expansion. The growth is set to continue, rising from $5.97 billion in 2024 to $6.75 billion in 2025, representing a Compound Annual Growth Rate (CAGR) of 13.0%. Factors that have contributed to this growth during the historic period include increasing research into genetic therapies, initial advances in RNA interference, a higher occurrence of genetic disorders, elevated investments in biotechnology, and expanding capabilities in biopharmaceutical manufacturing._x000D_

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The gene silencing industry is anticipated to witness significant expansion in the coming years, reaching a market value of $10.95 billion in 2029 with a compound annual growth rate (CAGR) of 12.9%. Multiple factors can be attributed to this projected growth during the forecasted period such as the broadening application in treating rare diseases, advances in delivery technologies, rising demand for personalized medicine, encouraging government policies, and increasing collaborations between pharmaceutical and biotech firms. The forecast period is set to see major trends including progress in targeted gene therapies, the prevalence of CRISPR-based silencing techniques, heightened focus on rare and orphan diseases, the inception of nanoparticle delivery methods, and broadening scope in the domain of agricultural gene silencing applications._x000D_

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#Which Primay Drivers Are Accelerating Growth in the Gene Silencing Market?#_x000D_

The escalating cases of genetic disorders are set to drive the growth of the gene silencing market forward. Genetic disorders are health conditions triggered by irregularities in a person’s DNA and are being recognized more and more due to progress in diagnostic technologies, increased consciousness, and wider access to genetic tests. The surge in genetic disorders is accredited to the rising age of parents, this heightens the likelihood of transmitting genetic mutations to their children. Gene silencing provides an encouraging method to treat genetic disorders by selectively ceasing the expression of defective or disease-causing genes. For example, as reported in August 2023 by Down Syndrome UK, a UK-focused charity, an estimated 40,000 people in the UK are affected by Down syndrome, with the condition occurring in roughly 1 in every 800 babies born. Hence, the escalating prevalence of genetic disorders is fuelling the growth of the gene silencing market._x000D_

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#Which Primary Segments of the Gene Silencing Market Are Driving Growth and Industry Transformations?#_x000D_

The gene silencing market covered in this report is segmented –_x000D_

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1) By Type: Transcriptional, Post-Transcriptional, Meiotic_x000D_

2) By Gene Silencing: RNA Interference (RNAi), Antisense Oligonucleotides (ASOs), Clustered Regularly Interspaced Short Palindromic Repeats(CRISPR) Or Cas9 -Based Gene Silencing, Other Gene Silencings_x000D_

3) By Application: Neurology, Oncology, Infectious Diseases, Metabolic Diseases, Therapeutics Manufacturing, Other Applications_x000D_

4) By End-Users: Pharmaceutical And Biotechnology Companies, Research Institutes and Academic Centers, Hospitals, Clinics, Other End-Users_x000D_

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Subsegments:_x000D_

1) By Transcriptional: DNA Methylation, Histone Modification_x000D_

2) By Post-Transcriptional: RNA Interference (RNAi), Antisense Oligonucleotides, MicroRNA (miRNA) Mediated Silencing_x000D_

3) By Meiotic: Meiotic Gene Conversion, Transposable Element Silencing_x000D_

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#Which Regions Are Key Players in the Growth of the Gene Silencing Market?#_x000D_

North America was the largest region in the gene silencing market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the gene silencing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa._x000D_

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#Which Technological Trends Are Reshaping the Gene Silencing Industry Dynamics?#_x000D_

Leading companies within the gene silencing market are centralizing their efforts on innovating breakthrough technologies, including small interfering RNA (siRNA), as a way of improving accuracy and efficiency in gene therapy. Small interfering RNA (siRNA) is a class of RNA molecule with a pivotal function in the RNA interference (RNAi) pathway. This entails binding to specified messenger RNA (mRNA) and favoring its breakdown, thereby stopping the formation of proteins linked to diseases. For instance, Judo Bio Inc., a biotech company based in the US, in October 2024, rolled out siRNA, an advanced drug that utilizes small interfering RNA (siRNA) to put genes into silence. This advanced product entails singular features including proprietary delivery systems such as lipid nanoparticles or associated ligands, and AI-driven platforms guarantee effective uptake by specific cells or tissues and expedite the process of finding feasible gene targets._x000D_

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#What Parameters Are Used to Define the Gene Silencing Market?#_x000D_

Gene silencing is a biological process in which the expression of a specific gene is reduced or completely turned off. The process is critical in regulating gene activity, controlling development, and defending against viral infections. Gene silencing is essential in research and medicine, particularly for targeting disease-related genes._x000D_

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