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How has the opdualag market grown in recent years?

The size of the opdualag market has undergone XX (HCAGR) of growth in the latest years. From 2024, it is projected to expand from $XX million to $XX million in 2025, achieving a compound annual growth rate (CAGR) of XX%. The upsurge during the historical phase can be linked to an increased frequency of advanced melanoma, enhanced healthcare knowledge, improved survival rates from cancer, governmental financial backing and assistance, as well as a surge in instances of exposure to ultraviolet radiation.

How is the opdualag market size expected to evolve during the forecast period?

The market size of opdualag is anticipated to witness a FCAGR of XX over the upcoming years, culminating in a projected worth of $XX million by 2029, with an associated CAGR of XX%. The projected growth during this period is credited to the escalating demand for enhanced diagnostic approaches, the increasing acceptance of intralesional therapy, progressing clinical trials and regulatory green lights paving the way for new treatments. Other significant aspects include the ageing population growth and the rise in melanoma cases. Key trends to watch in the forecast period include the implementation of immunotherapy, combined therapies, tailored cancer treatment, biosimilar development, and the integration of digital tools in cancer management.

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Which key drivers are propelling the opdualag market’s growth?

The opdualag market is set to expand due to the rising occurrences of advanced melanoma. Advanced melanoma refers to the stage of the cancer where it has spread beyond the skin to other areas of the body such as the lymph nodes, organs, or distant tissues. Factors such as increased sun exposure and genetics, along with improved detection through screening, contribute to the rising incidence of advanced melanoma. Opdualag, a combination of nivolumab and relatlimab, enhances immune response and provides targeted treatment for metastases, thus helping to prevent the progress of advanced melanoma. For example, Cancer Research UK, an independent cancer charity based in the UK, issued reports in July 2024 suggesting a considerable increase in new melanoma skin cancer cases. The annual incidents are expected to rise from roughly 20,800 cases reported during 2023-2025 to an estimated 26,500 cases by 2038-2040. Consequently, the escalation in advanced melanoma incidence is steering the growth of the opdualag market.

What are the market segments in the opdualag industry?

The opdualag market covered in this report is segmented –

1) By Clinical Indications: Non-Small Cell Lung Cancer (NSCLC); Melanoma; Mismatched Repair Deficient Or Microsatellite Instability-High; Squamous Cell Carcinoma Of The Head And Neck (SCCHN); Renal Cell Carcinoma (RCC); Classical Hodgkin Lymphoma (cHL); Unrothelial Carcinoma (UC)

2) By Distribution Channel: Direct Sales; Online Pharmacies; Wholesale Distributors

3) By End User: Hospitals; Oncology Clinics; Pharmaceutical Distributors

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Which leading companies are shaping the growth of the opdualag market?

Major companies operating in the opdualag market are Bristol-Myers Squibb Company

What key trends are currently impacting the opdualag market’s development?

The prominent trend in the opdualag market involves the advancement of dual immunotherapy combination treatment, fostering enhanced effectiveness in cancer treatment and yielding improved clinical results for patients. This approach involves the utilization of two unique immune-targeting therapies to amplify the body’s immune reaction against cancer by targetting multiple immune checkpoints or pathways for superior tumor control. For instance, Bristol Myers Squibb, a US biopharmaceutical organization, in September 2022 declared that the European Commission (EC) approved Opdualag. This treatment, comprising of the PD-1 inhibitor nivolumab and the LAG-3-blocking antibody relatlimab, is specifically endorsed for adults and adolescents aged 12 and above with non-resectable or metastatic melanoma displaying low tumor cell PD-L1 expression (less than 1%). This approval was based upon the data from the Phase 2/3 RELATIVITY-047 trial, indicating that patients treated with Opdualag showed a median progression-free survival of 10.1 months, significantly exceeding the 4.6 months observed with nivolumab alone.

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Which geographic areas are influencing the growth of the opdualag market?

North America was the largest region in the opdualag market in 2024. The regions covered in the opdualag market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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