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What fueled the previous growth in the personalized cancer vaccines market?

The personalized cancer vaccines market has demonstrated strong growth, rising from $242.29 billion in 2024 to $259.11 billion in 2025, with a CAGR of 6.9%. Factors driving past expansion include progress in genomic research, the development of targeted therapies, improved understanding of tumor immunology, advancements in vaccine technology, and increasing clinical trial data supporting vaccine efficacy.

What will be the personalized cancer vaccines market size in the future?

The personalized cancer vaccines market is expected to see strong expansion, reaching $336.03 billion by 2029 at a CAGR of 6.7%. Growth factors include precision medicine advancements, increased cancer research funding, rising cancer prevalence, improvements in genetic sequencing, and growing interest in personalized treatment. Major trends involve AI integration in vaccine development, advances in multi-antigen and neoantigen-based vaccines, liquid biopsy applications, expansion of combination therapies, and a greater emphasis on personalized regimens.

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What main drivers are fueling expansion in the personalized cancer vaccines market?

The increasing cancer prevalence is also expected to boost the growth of the personalized cancer vaccine market. Cancer is a collection of diseases marked by abnormal cell growth, and its rising prevalence is due to aging populations, lifestyle changes, and genetic factors. Personalized cancer vaccines target specific tumor antigens to strengthen the immune system’s ability to combat cancer. In July 2024, the Australian Institute of Health and Welfare reported that cancer diagnoses in Australia rose from 160,570 in 2022 to 164,694 in 2023, marking a significant increase. Thus, the growing cancer prevalence is driving the personalized cancer vaccine market.

What key areas define the segmentation of the global personalized cancer vaccines market?

The personalized cancer vaccinesmarket covered in this report is segmented –

1) By Treatment Type: Preventive Cancer Vaccines, Therapeutic Cancer Vaccines

2) By Cancer Type: Lung Cancer, Breast Cancer, Colorectal Cancer, Leukemia, Prostate Cancer, Cervical Cancer, Glioblastoma

3) By Mechanism Of Action: Tumor Associated Antigens (TAAs), Tumor Specific Antigens (TSAs), Somatic Mutations In Cancer Pharmacogenomics, Pharmacogenomics Towards Genomic Polymorphism, Other Mechanisms Of Action

4) By Route Of Administration: Injectables, Other Routes Of Administration

5) By End Use: Hospitals, Clinic, Other End Users

Subsegments:

1) By Preventive Cancer Vaccines: HPV Vaccines, Hepatitis B Vaccines, Combination Vaccines

2) By Therapeutic Cancer Vaccines: Dendritic Cell Vaccines, Peptide-Based Vaccines, DNA Vaccines, RNA Vaccines, Whole Cell Vaccines

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Who are the dominant players expanding their reach in the personalized cancer vaccines market?

Major companies operating in the personalized cancer vaccines market are Merck & Co Inc., GlaxoSmithKline Plc, NEC Corporation, Moderna Inc., Catalent Inc., UCLA Health, Genetech Inc., NHS England, CureVac AG, Personalis Inc., Achilles Therapeutics Plc, Healio, Moffitt Corporation, BioPharma APAC, Celebrity Angels, EpiVax Therapeutics Inc., Evaxion Biotech AS, Geneos Therapeutics Inc., IFL Sciense, ISA Pharmaceuticals BV, Oxford Global, Kintara Therapeutics, VAXIMM Gmbh

How are evolving market trends shaping personalized cancer vaccines Strategies?

Significant companies in the personalized cancer vaccine market are concentrating on the evolution of advanced therapeutic strategies, such as personalized immunotherapy, for precision in treating specific cancer mutations. These novel solutions are tailored treatments designed according to a patient’s unique genetic and tumor profile to augment the immune system’s reactions to cancer. For example, in August 2024, UCLA Health, a healthcare organization based in the United States, initiated a groundbreaking clinical trial to assess the safety and efficiency of a new cancer vaccine. This vaccine, developed at UCLA, employs a personalized immunotherapy method that targets the H3 G34 mutation discovered in diffuse hemispheric gliomas, a notably aggressive brain tumor commonly diagnosed in adolescents and young adults. The method uniquely engages dendritic cells to trigger the immune system against the specific RNA disruptions generated by this mutation. This innovative approach, which has demonstrated potential in treating other cancers, intends to enhance prognosis for patients typically subjected to restricted treatment alternatives and brief survival periods.

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Which regions are emerging as leaders in the personalized cancer vaccines market?

North America was the largest region in the personalized cancer vaccines market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the personalized cancer vaccines market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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