Global Hepatorenal Syndrome Treatment Market
Pharmaceuticals

Hepatorenal Syndrome Treatment Market Analysis: Key Insights on Growth Rates, Trends, and Major Opportunities

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How has the hepatorenal syndrome treatment market grown in recent years?

The market for hepatorenal syndrome treatment has seen a considerable expansion in the past few years. The market size is set to surge from $14.49 billion in 2024 to $15.31 billion in 2025, with a compound annual growth rate (CAGR) of 5.7%. The increase during the historical period is due to factors such as growth in the automotive industry, demands in the aerospace sector, benefits in material usage, enhanced mechanical properties, strict industry standards, and gains in efficiency and precision.

How is the hepatorenal syndrome treatment market size expected to evolve during the forecast period?

The market size for hepatorenal syndrome treatment is predicted to experience considerable expansion in the coming years. The projected size is an impressive “$19.94 billion by 2029, growing at a compound annual growth rate (CAGR) of 6.8%. The projected escalation during the forecast period can be credited to a surge in renewable energy projects, an increased need for high-performance alloys, emphasis on eco-friendly manufacturing, further experiments in oil and gas exploration, and the need for superior performance components. Key trends predicted for the forecast period are the integration of Industry 4.0 technologies, advances in forging methodologies, custom made solutions for specific applications, automation within forging procedures, and breakthroughs in heating and cooling technology.

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Which key drivers are propelling the hepatorenal syndrome treatment market’s growth?

The anticipated rise in cases of liver damage or cirrhosis is forecasted to fuel the growth of the hepatorenal syndrome treatment market. Cirrhosis, characterized by the permanent replacement of healthy liver tissue with scar tissue, is a critical form of liver disease. The goal of hepatorenal syndrome treatment is to preserve kidney functionality in patients and reduce the symptoms and negative consequences associated with the disease, thereby enhancing overall health and making patients more suitable for liver transplant surgery. For example, data from the British Liver Trust, a charity based in the UK, showed in July 2023 that there was a 22% increase in hospital admissions related to liver disease in England in one year. According to these figures, the total elevations increased from 67,458 in 2021 to 82,290 at the end of the fiscal year 2022. Thus, the rising prevalence of liver damage or cirrhosis is a significant factor propelling the expansion of the hepatorenal syndrome treatment market.

What are the market segments in the hepatorenal syndrome treatment industry?

The hepatorenal syndrome treatment market covered in this report is segmented –

1) By Type: Type 1 Hepatorenal Syndrome, Type 2 Hepatorenal Syndrome

2) By Treatment: Therapeutics, Surgical Treatment

3) By End-User: Hospitals And Clinics, Ambulatory Surgical Centers, Academic And Research Institutes, Other End-Users

Subsegments:

1) By Type 1 Hepatorenal Syndrome: Intravenous Albumin, Vasopressors, Dialysis, Liver Transplantation

2) By Type 2 Hepatorenal Syndrome: Albumin Infusion, Midodrine, Octreotide, Liver Transplantation

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Which leading companies are shaping the growth of the hepatorenal syndrome treatment market?

Major companies operating in the hepatorenal syndrome treatment market include BioVie Inc., Cumberland Pharmaceuticals Inc., Mallinckrodt Pharmaceuticals, Orphan Therapeutics LLC, Baxter International Inc., La Jolla Pharmaceutical Company, Noorik Biopharmaceuticals AG, Novartis AG, Zydus Lifesciences Limited, Ocelot Bio Inc., New Medicon Pharma Lab Private Limited, Arrowhead Pharmaceuticals, Stealth BioTherapeutics Inc., Eli Lilly and Company, Teva Pharmaceutical Industries Ltd., Vertex Pharmaceuticals Inc., Johnson & Johnson, Boehringer Ingelheim GmbH, Catalyst Pharmaceuticals Inc., Bayer AG, Gilead Sciences Inc.

What key trends are currently impacting the hepatorenal syndrome treatment market’s development?

The hepatorenal syndrome treatment market is seeing a rising trend in research and development activities. As firms seek to maintain their market standing, they are placing a higher emphasis on these endeavours. For instance, in September 2022, Mallinckrodt Pharmaceuticals, an Irish company noted for developing, producing, and distributing specialty therapies and products, secured FDA approval for Terlivaz, a therapeutic injection for adults suffering from kidney function related to hepatorenal syndrome. An important contributor to this approval was the Phase 3 CONFIRM trial, the largest prospect research ever conducted (with 300 participants) to assess the safety and efficiency of terlipressin in HRS type 1 (HRS-1) patients in the U.S. and Canada. The CONFIRM trial’s main endpoint, Verified HRS Reversal, which was marked by improvements in renal function, elimination of the need for dialysis, and short-term survival, was successful (p=0.012).

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Which geographic areas are influencing the growth of the hepatorenal syndrome treatment market?

North America was the largest region in the hepatorenal syndrome treatment market in 2024. Asia-Pacific is expected to be the fastest-growing region in the global hepatorenal syndrome treatment market during the forecast period. The regions covered in the hepatorenal syndrome treatment market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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