Discover trends, market shifts, and competitive outlooks for the herg screening industry through 2025-2034 with The Business Research Company’s reliable data and in-depth research

What Is the Current and Projected Market Size of the HERG Screening Market Through 2034?

There has been a substantial expansion in the size of the HERG screening market in recent times. It is forecasted to inflate from $1.62 billion in 2024 to $1.84 billion in 2025, yielding a compound annual growth rate (CAGR) of 13.9%. This development over the historic period can be linked to the escalation of drug advancement activities, adherence to regulatory policies, growing consciousness regarding cardiac safety, and the surge in cardiac disorder cases.

Expectations for the HERG screening market project a swift expansion in the coming years, with a predicted valuation of $2.9 billion by 2029, reflecting a compound annual growth rate (CAGR) of 12.0%. The anticipated growth over the forecast period can be linked to the broadening scope of personalized medicine, a rise in the outsourcing of drug development activities, the advent of emerging markets and research, and more emphasis on non-cardiac safety evaluations. Forecast period trends comprise progressive in vitro models, the amalgamation of genomic and proteomic data, breakthroughs in computational methodologies, increased attention to pediatric drug safety, and partnerships for data exchange and standardization.

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What Are the Core Growth Drivers Propelling the HERG Screening Market Forward?

The escalating prevalence of heart-related disorders is anticipated to fuel the expansion of the HERG screening market. Also referred to as cardiovascular disorders or diseases, heart ailments encompass conditions that deteriorate the functionality of the heart and blood vessels. These conditions can precipitate serious health consequences. Poor lifestyle choices, aging demographics, genetic predispositions, diabetes, and metabolic syndrome are all factors contributing to these disorders. HERG screening is instrumental in recognizing prospective drug candidates, avert deleterious cardiac incidents leading to potentially fatal cardiac arrhythmias like torsade de pointes (TdP), and enhance patient prognosis. For example, in May 2023, the Centers for Disease Control and Prevention, a US-based national public health agency, published a report stating that 1 in 20 adults aged 20 and above were diagnosed with cardiovascular diseases. The report also noted that during that year, 695,000 were afflicted with cardiovascular diseases and 375,476 individuals succumbed to these ailments. Additionally, in March 2022, the Office for National Statistics, a UK-based government department, reported that there were 20,061 deaths due to heart attacks, a rise from the preceding year. Consequently, the surging number of individuals with heart disorders is propelling the growth of the HERG screening market.

What Segment Types Define the HERG Screening Market Structure?

The HERG screening market covered in this report is segmented –

1) By Type: Gene KCNH2, Mutant KCNH2

2) By Ion Channel: Voltage-Gated, Ligand Gated

3) By Applications: Antiarrhythmic, Antipsychotic, Antibiotics, Other Applications

Subsegmeents:

1) By Gene KCNH2: Wild-Type KCNH2, Recombinant KCNH2

2) By Mutant KCNH2: Mutations: Missense Mutations, Nonsense Mutations, Frameshift Mutations

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Which Geographic Areas Hold the Strongest Growth Potential in the HERG Screening Market?

North America was the largest region in the HERG screening market in 2024. Asia-Pacific is expected to be the fastest growing region in the forecast period. The regions covered in the HERG screening market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

Which Emerging Trends that Are Influencing theHERG Screening Industry Evolution?

Leading businesses in the HERG screening market are focusing on the development and introduction of innovative high-tech solutions like GLP-certified HERG screening services. These services aim to improve cardiac safety assessments during drug development procedures. This GLP-certified service involves conducting the screening of the human ether-à-go-go related gene (hERG) using the established whole-cell patch-clamp method in line with regulatory guidelines such as ICH S7A and ICH S7B. These guidelines are crucial for safety pharmacology research during drug development. An example of this, Metrion Biosciences Ltd., a pharmaceutical company based in the UK, introduced GLP-certified hERG screening service in August 2023. The purpose of this service is to augment Metrion’s assistance in the development of small-molecule therapeutics and to bolster its current cardiac safety service range. Moreover, this service deploys the standard whole-cell patch-clamp technique to examine potential cardiac risks before conducting Phase 1 clinical trials on humans. Additionally, it imparts regulatory advice for safety pharmacology investigations in drug development and provides clients with top-notch biology services for ion channel targets.

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What Is the Definition of the HERG Screening Market?

Human Ether-à-go-go-related gene (HERG) screening refers to the process of assessing the potential cardiotoxicity of a drug or compound. HERG screening is an important component of preclinical safety assessment in drug discovery and development, ensuring the safety and efficacy of novel therapeutic agents.

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