Understanding Key Drivers and Growth Opportunities in the HERG Screening Market: Trends and Market Size Insights
2025 Market Reports Update: Market Size Forecasts to 2034, Key Trends, Leading Players, and Top Regions – Get Ahead of the Competition Today!
What Factors Are Propelling the Market Growth of theHERG Screening Market from 2025 to 2034?
The growth of the HERG screening market is anticipated to be fueled by the increasing number of individuals suffering from heart disorders. Heart disorders, alternatively known as cardiovascular diseases, encompass an array of conditions affecting the heart and blood vessels. These conditions can interfere with the heart’s normal functioning, leading to potentially severe health issues. Unhealthy lifestyles, aging, genetic predisposition, diabetes, and metabolic syndrome are primary contributors to these disorders. HERG screening plays a significant role in identifying promising drug candidates, averting cardiac events that could provoke fatal cardiac arrhythmias, notably torsade de pointes (TdP), and enhancing patient health outcomes. For instance, a report released by the Centers for Disease Control and Prevention, a US-based national public health agency, in May 2023 stated that 1 in 20 adults over 20 years have cardiovascular diseases. The report further noted that 695,000 individuals had cardiovascular diseases, with 375,476 of them succumbing to these diseases. Additionally, a report from the Office for National Statistics, a UK government department, in March 2022 pointed out that 20,061 people died from heart attacks, marking an increase from the previous year. Hence, the escalating numbers of heart disorder patients are stimulating the expansion of the HERG screening market.
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#What Growth Opportunities Will Drive the HERG Screening Market’s CAGR Through 2034?
In recent times, the HERG screening market experienced a significant expansion. The market value, projected to increase from $1.62 billion in 2024 to $1.84 billion in 2025, is expected to grow at a compound annual growth rate (CAGR) of 13.9%. The historic growth trend is chiefly due to the rise in drug development efforts, changing governmental regulations, a growing focus on cardiac health safety, and a spike in heart-related ailments.
Expectations are high for the HERG screening market as it is forecasted to experience swift growth in the coming years. The projected growth could see the market reach $2.9 billion by 2029, with a compound annual growth rate (CAGR) of 12.0%. This growth in the forecast period is anticipated to be fuelled by the growth of personalized medicine, the rise in drug development outsourcing activities, and the expansion of emerging markets and research. The emphasis on non-cardiac safety assessments is another growth driver. Notable trends for the forecast period are the progression of in vitro models, the synergy of genomic and proteomic data, advancements in computational strategies, a focus on the safety of pediatric medicines, and collaborative measures for data sharing and standardization.
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How Are Market Trends and Innovations Revolutionizing theHERG Screening Industry in Recent Times?
Leading firms in the HERG screening market are focusing on cutting-edge solutions, including GLP-certified HERG screening services, to improve cardiac safety evaluations during drug creation procedures. This service involves good laboratory practice-certified screening of the human ether-à-go-go related gene (hERG) utilizing the traditional whole-cell patch-clamp method. It guarantees that the screening adheres to regulatory standards such as ICH S7A and ICH S7B, which are crucial for safety pharmacology research in drug development. For example, Metrion Biosciences Ltd., a pharmaceutical company based in the UK, unveiled the good laboratory practice (GLP)-certified hERG screening service in August 2023. The purpose of this service is to strengthen Metrion’s contribution to small-molecule therapeutic creation and enhance the company’s existing cardiac safety service offerings. Besides, this service uses the traditional whole-cell patch-clamp method to identify potential cardiac risks before beginning Phase 1 clinical trials in humans. It also provides regulatory advice for safety pharmacology research in drug development and delivers customers top-quality biology services for ion channel objectives.
Which Key Market Players Are Shaping the Future and Growth of theHERG Screening Market?
Major companies operating in the HERG screening market are Eurofins-Cerep SA., Aviva Biosciences Inc., AstraZeneca Public Limited Company, Merck KGaA, Charles River Laboratories Inc., Abcam Public Limited Company, Molecular Devices LLC, Caliper Life Sciences Inc., Crprotex Limited, ChanTest Corporation, Creative bioarray Inc., Cellular Dynamics International Inc., Nanion Technologies, Essen Bioscience, ABR-Affinity BioReagents Inc., ACEA Biosciences Inc., Metrion biosciences Inc., Aurora Biomed Inc., Aureus Sciences, RedShift BioAnalytics, B’SYS GmbH, Cambridge Bioscience Ltd., Sophion Bioscience Inc., Fluxion Biosciences Inc., ChemAxon Ltd.
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What Are the Core Segments of the HERG Screening Market, and How Do They Contribute to Growth?
The HERG screening market covered in this report is segmented –
1) By Type: Gene KCNH2, Mutant KCNH2
2) By Ion Channel: Voltage-Gated, Ligand Gated
3) By Applications: Antiarrhythmic, Antipsychotic, Antibiotics, Other Applications
Subsegmeents:
1) By Gene KCNH2: Wild-Type KCNH2, Recombinant KCNH2
2) By Mutant KCNH2: Mutations: Missense Mutations, Nonsense Mutations, Frameshift Mutations
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What Regions Are Dominating the HERG Screening Market Growth?
North America was the largest region in the HERG screening market in 2024. Asia-Pacific is expected to be the fastest growing region in the forecast period. The regions covered in the HERG screening market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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