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What Growth Opportunities are Expected to Drive the Human Liver Model Market’s CAGR Through 2034?

The human liver model market has grown rapidly in recent years, projected to rise from $2.34 billion in 2024 to $2.63 billion in 2025, with a CAGR of 12.2%. The key factors driving historical growth include the need for drug development, advancements in biotechnology, alternatives to animal testing, increasing liver disease prevalence, and regulatory requirements.

The human liver model market is set to grow rapidly, reaching $4.41 billion by 2029 at a CAGR of 13.8%. Growth drivers include the integration of AI and machine learning, advancements in patient-derived liver models, breakthroughs in bioengineering, increasing requirements for drug safety and toxicity testing, and the emergence of virtual clinical trials. Notable trends in the forecast period include the development of multi-organ models, innovations in 3D bioprinting, enhanced high-throughput screening capabilities, improvements in vascularization and blood flow, and a strong focus on ethical and regulatory compliance.

Which Drivers Are Expected to Have the Greatest Impact on the human liver model Market’s Growth?

The increasing prevalence of liver disease is expected to drive the growth of the human liver model market. Liver disease encompasses a range of disorders that affect the liver’s function or cause it to fail. Human liver models are emerging as valuable tools for advancing research in liver diseases and drug development. Consequently, the rising incidence of liver diseases is fostering growth in the human liver model market. For example, in September 2022, Cancer Australia, a government cancer agency in Australia, reported that approximately 2,905 new cases of liver cancer were diagnosed in the country in 2022, with 2,113 cases among males and 792 among females. Furthermore, the lifetime risk of developing liver cancer was estimated at 1 in 103 (0.97%) overall, 1 in 70 (1.4%) for men, and 1 in 195 (0.51%) for women. Therefore, the growing occurrence of liver disease is propelling the human liver model market.

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What Are the Leading Industry Players Dominating the Human Liver Model Market?

Major companies operating in the human liver model market include:

• Corning Incorporated_x000D_

• EISCO Scientific LLC_x000D_

• BioIVT LLC_x000D_

• Cyprotex plc_x000D_

• Emulate Inc._x000D_

What Are the Latest Trends Leading to Disruption in the Human Liver Model Market?

Product innovation is a key trend in the human liver model market. Companies are focusing on creating innovative products to strengthen their market position. For example, in April 2023, LifeNet Health Life Sciences, a US-based provider of human cell and tissue-based solutions, launched TruVivo, a cutting-edge liver system made entirely from human cells. This 2D+ solution merges the benefits of 3D models with the flexibility of 2D models, facilitating drug research and development.

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What Are the Strategic Segments Comprising the Human Liver Model Market and Their Growth Contributions?

The human liver model market covered in this report is segmented –

1) By Product: Liver Organoids, Liver-On-A-Chip, 2D Models, Animal Models, 3D Bioprinting

2) By Application: Educational, Drug Discovery, Other Applications

3) By End Users: Research Institutes, Pharmaceutical Companies, Other End Users

Subsegments:

1) By Liver Organoids: Primary Liver Organoids, Induced Pluripotent Stem Cell (iPSC)-Derived Organoids

2) By Liver-On-A-Chip: Microfluidic Liver Chips, Multi-Organ Chip Systems

3) By 2D Models: Liver Cell Cultures, Liver Cell Lines

4) By Animal Models: Rodent Models, Large Animal Models

5) By 3D Bioprinting: Bioprinted Liver Tissues, Hybrid Bioprinted Models

Which Regions Are Significant to the Growth of the Human Liver Model Market?

North America was the largest region in the human liver model market in 2024. The regions covered in the human liver model market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

How Can We Define the Human Liver Model Market and Its Key Components?

The human liver model refers to the model of dual-lobed liver of humans that is primarily in charge of filtering blood from the digestive tract. It is used to show and evaluate the toxic effects of drug candidates on the liver.

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