The Business Research Company’s global market reports are now updated with the latest market sizing information for the year 2024 and forecasted to 2033

The in vitro lung model market has experienced substantial growth in recent years, driven by various factors and technological advancements. Here’s an overview of the market size, growth drivers, trends, and major players shaping the future of this industry.

Market Size and Growth Rates

• 2023-2024 Growth: The in vitro lung model market is expected to grow from $0.37 billion in 2023 to $0.44 billion in 2024, at a compound annual growth rate (CAGR) of 21%.
• 2024-2028 Projections: The market is forecasted to reach $0.96 billion by 2028, continuing its robust growth with a CAGR of 21.1%.

Key Drivers of Market Growth

• Growing Prevalence of Respiratory Diseases: The rising incidence of respiratory illnesses is fueling demand for advanced research models.
• Personalized and Precision Medicine: Increased focus on personalized and precision medicine approaches has highlighted the need for accurate in vitro lung models.
• Drug Development and Preclinical Testing: The growing necessity for drug testing and the development of new treatments are driving the market.
• Environmental Health Awareness: Greater awareness of environmental health risks and respiratory toxicology is boosting demand for in vitro models.

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Technological Trends Shaping the Market

• 3D Printing and Organ-on-Chip Technologies: Advancements in these areas are enhancing the physiological relevance of lung models, allowing for more accurate simulation of human lung function.
• Artificial Intelligence (AI) and Machine Learning: These technologies are being integrated to improve predictive analytics and model accuracy.
• Expansion Beyond Pharmaceuticals: There’s an increasing use of in vitro lung models in areas like environmental research and consumer product testing.

Increasing Clinical Studies Propel Market Growth

• Role of Clinical Trials: In vitro lung models are becoming essential in clinical trials, providing a controlled environment to study the effects of substances on lung tissue. This is vital for drug testing, toxicity assessments, and understanding disease mechanisms.
• Rising Number of Trials: For example, as of January 2024, there were 477,230 clinical trials registered globally on ClinicalTrials.gov, up from 437,508 in 2022. This growth in clinical studies significantly boosts the in vitro lung model market.

Major Companies and Market Leaders

• Key Players: Leading companies in the market include Thermo Fisher Scientific Inc., Lonza Group AG, PerkinElmer Inc., Charles River Laboratories International Inc., and Epithelix. These companies are at the forefront of innovation, developing new models and expanding applications.

Advancements in 3D Respiratory Tissue Models

• Development of 3D Models: Major companies are focusing on creating more complex 3D respiratory tissue models that mimic the lung’s structure and function more closely.
• Case Study – MatTek Corporation: In April 2023, MatTek introduced EpiNasal, a 3D respiratory tissue model made from human nasal epithelial cells. This model provides a realistic platform for studying pharmaceuticals, chemicals, and pathogens, expanding the company’s portfolio and market influence.

Strategic Acquisitions to Drive Innovation

• CELLINK Acquires MatTek Corporation: In March 2021, CELLINK acquired MatTek Corporation to enhance its capabilities in developing ethical alternative test models, reducing the reliance on animal testing. This acquisition aligns with CELLINK’s goal of revolutionizing medicine through accurate and ethical testing models.

Market Segmentation

• By Type: The market is divided into two-dimensional (2D) and three-dimensional (3D) models.
• By Application: Applications include drug discovery and toxicology studies, physiological research, 3D model development, and other applications.
• By End-User: End-users range from academic research institutes to pharmaceutical and biotechnology companies.

Regional Insights

• North America: Was the largest region in the in vitro lung model market in 2023.
• Asia-Pacific: Expected to be the fastest-growing region during the forecast period, driven by increasing healthcare investments and research activities.

The in vitro lung model market is on a growth trajectory, propelled by technological advancements, increased research activities, and the rising demand for ethical and precise testing models. With continued innovation and expanding applications, the market is set to play a crucial role in advancing respiratory health research and development.

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